The preparation of compound metronidazole gel

Key words: 
• metronidazole /
• dexamethasone sodium phosphate /
• gel /
• convolution curve method

Abstract: The gel of compound metronidazole is at ransparent hydrophilic gel of carbomer 940,which consist of metronidazole and dexamethasone sodium phosphate.It is used topically to treat aphthous ulcer and peridental inflammation.We reported the preformulation,method of preparation,quantitative determination and the standard for quality of the gel in this paper.The metronidazole and dexamethasone sodium phosphate in the gel were analysed by the computer-aided convolution cure method without prior separation.These methods are simple and rapid.