Comparative serum levels of AMIRACIN determined by microbiological and fluorescence polarization immunoassay methods

Key words: 
• amikacin /
• microbiological method /
• fluorescence Polarization immunoassay method.linear relation /

Abstract: Serum levels of amikacin in 15 cases of healthy adult volunteers after intramuscular administration were determined by microbiological method (BA) and fluorescence polarization immunoassay method (FPIA).The result of all 104 serum samples showed that the serum levels of amikacin determined by FPIA method were significantly higher than those determined by the BA method(P<0.01)the linear relation between these two groups was as follow:Y=1.7755+0.9497×(r=0.9968).It suggested that monitoring the serum levet of amikacin by the two methods had no difference.