Study on the pyrogen detection of injection gentamycin sulfate with the method of tachypleus amebocyte lysate test

Key words: 
• Injection Gentamycin Sulfate /
• pyrogen /
• endotoxin /
• tachypleus amebocyte lysate for endotoxin (pyrogen) detection

Abstract: Through the test of interfere to the process of agglutinate reaction with Injection Gentamycin Sulfate which have been forty times diluted.This experiment proved that there is no interference (not excessed ±2λ) to the sensitive of Tachypleus Amebocyte Lysate for Endotoxin (Purogen) Detection (λ=05EU/ml). On the basis of this experiment.a new method can be established for pyrogen detection or applying to primary screening instead of the traditional rabbit test.This method may raise the efficiency and sensitivety of pyrogen test greatly.There will be particularly for drug production manufactured a important reference significance.