Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 13 Issue 1
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 1995  >  (1): 8-12

Wang Rui, Zhao Zhi-jian, Chen Qian, Li Yong, Zhang Yuan-zheng, Tan Ci-e, Pei Bao-xiang, Chen Meng-li. Comparision of bactericidal activity in cerebrospinal fluid of three cephalosporins in the patients undergoing surgery of skull and brain[J]. Journal of Pharmaceutical Practice and Service, 1995, (1): 8-12.
Citation: Wang Rui, Zhao Zhi-jian, Chen Qian, Li Yong, Zhang Yuan-zheng, Tan Ci-e, Pei Bao-xiang, Chen Meng-li. Comparision of bactericidal activity in cerebrospinal fluid of three cephalosporins in the patients undergoing surgery of skull and brain[J]. Journal of Pharmaceutical Practice and Service, 1995, (1): 8-12.
shu

Comparision of bactericidal activity in cerebrospinal fluid of three cephalosporins in the patients undergoing surgery of skull and brain

  • Chinese PLA General Hospital Dept.Clinical Pharmacology Beijing 100853

  • The bactericidal activity of serum and cerebrospinal fluid(SBA and CBA) of ceftriaxone(CTRX、cefotaxime(CTX))、cefuroxime(CFR)in the patients undergoing surgery of skull and brain were studied by means of microdiluted method.The results showed antibacterial activity of CTRX against Enterobactericeae in vitro or in serum and cerebrospinal fluid(CSF) was the highest,it is suggested that the schadule of lg of CTRX per 12hr may be used in prevention and treatment of serious infections after surgery of skull and brain.The bactericidal activity of CTX against Gram's positive strains and Enterobactericeae in serum and CSF were higher,CTX may be used in infections of nervous system caused by mixed bacteria.The SBA and CBA of CFR were less,but its antibacterial spectrum was wide and the cost was lower,so CFR may be selected in the moderate infections.The CBA was a synthesized guide reflexing the antibactial activity and penetration into barrier,so it is recommanded reference to selected antibiotis infections after surgery of skull and brain.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(3413) PDF downloads(375) Cited by()

Related
Proportional views

Comparision of bactericidal activity in cerebrospinal fluid of three cephalosporins in the patients undergoing surgery of skull and brain

  • Chinese PLA General Hospital Dept.Clinical Pharmacology Beijing 100853

Abstract: The bactericidal activity of serum and cerebrospinal fluid(SBA and CBA) of ceftriaxone(CTRX、cefotaxime(CTX))、cefuroxime(CFR)in the patients undergoing surgery of skull and brain were studied by means of microdiluted method.The results showed antibacterial activity of CTRX against Enterobactericeae in vitro or in serum and cerebrospinal fluid(CSF) was the highest,it is suggested that the schadule of lg of CTRX per 12hr may be used in prevention and treatment of serious infections after surgery of skull and brain.The bactericidal activity of CTX against Gram's positive strains and Enterobactericeae in serum and CSF were higher,CTX may be used in infections of nervous system caused by mixed bacteria.The SBA and CBA of CFR were less,but its antibacterial spectrum was wide and the cost was lower,so CFR may be selected in the moderate infections.The CBA was a synthesized guide reflexing the antibactial activity and penetration into barrier,so it is recommanded reference to selected antibiotis infections after surgery of skull and brain.

Wang Rui, Zhao Zhi-jian, Chen Qian, Li Yong, Zhang Yuan-zheng, Tan Ci-e, Pei Bao-xiang, Chen Meng-li. Comparision of bactericidal activity in cerebrospinal fluid of three cephalosporins in the patients undergoing surgery of skull and brain[J]. Journal of Pharmaceutical Practice and Service, 1995, (1): 8-12.
Citation: Wang Rui, Zhao Zhi-jian, Chen Qian, Li Yong, Zhang Yuan-zheng, Tan Ci-e, Pei Bao-xiang, Chen Meng-li. Comparision of bactericidal activity in cerebrospinal fluid of three cephalosporins in the patients undergoing surgery of skull and brain[J]. Journal of Pharmaceutical Practice and Service, 1995, (1): 8-12.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return