ZHANG Shu-yu. Identification and determination of tanshinone ⅡA in Compound Granule Tetrandra[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 228-230. doi: 10.3969/j.issn.1006-0111.2013.03.020
| Citation:
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ZHANG Shu-yu. Identification and determination of tanshinone ⅡA in Compound Granule Tetrandra[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 228-230. doi: 10.3969/j.issn.1006-0111.2013.03.020
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Identification and determination of tanshinone ⅡA in Compound Granule Tetrandra
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Department of Pharmacy, Jinan Military General Hospital, Jinan, 250031, China
- Received Date: 2012-09-04
- Rev Recd Date:
2012-11-02
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Abstract
Objective To develop a method for identification and determination of tanshinone ⅡA in Compound Granule Tetrandra. Methods TLC method was used to identify tanshinone ⅡA, HPLC method was used to determine the content. Results The spot was clear in TLC identification without interference of negative control.The sample size of tanshinone ⅡA had a good linear relationship with peak area(r=0.999 9), when ranged from 5.28~52.8 μg/ml, the average recovery rate was 97.97%, RSD was 0.34%(n=9). Conclusion The method was simple, with good specificity and reproducibility, which could be used as the quality control method for this preparation.
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