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Volume 31 Issue 1
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2013  >  31(1): 19-21

ZHAO Xin-bin, NI Min, TAO Xia. Progress on the multiple pharmacological activity and mechanism of statins[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(1): 19-21. doi: 10.3969/j.issn.1006-0111.2013.01.005
Citation: ZHAO Xin-bin, NI Min, TAO Xia. Progress on the multiple pharmacological activity and mechanism of statins[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(1): 19-21. doi: 10.3969/j.issn.1006-0111.2013.01.005
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Progress on the multiple pharmacological activity and mechanism of statins

doi: 10.3969/j.issn.1006-0111.2013.01.005

  • Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China

  • Received Date: 2012-02-14
  • Rev Recd Date: 2012-04-05
  • Statins were a mainstay in the treatment of hyperlipidemia and used in the primary and secondary prevention of coronary artery disease. Recent studies indicated that there were some cholesterol-independent or pleiotropic effects of statins, including improving endothelial function, decreasing oxidative stress, inhibiting inflammation, enhancing the stability of atherosclerotic plaques and used for anticancer therapy. The effects and mechanisms of statins on vascular disease and cancer were reviewed in this paper.
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Progress on the multiple pharmacological activity and mechanism of statins

doi: 10.3969/j.issn.1006-0111.2013.01.005
  • Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
  • Received Date: 2012-02-14
  • Rev Recd Date: 2012-04-05

Abstract: Statins were a mainstay in the treatment of hyperlipidemia and used in the primary and secondary prevention of coronary artery disease. Recent studies indicated that there were some cholesterol-independent or pleiotropic effects of statins, including improving endothelial function, decreasing oxidative stress, inhibiting inflammation, enhancing the stability of atherosclerotic plaques and used for anticancer therapy. The effects and mechanisms of statins on vascular disease and cancer were reviewed in this paper.

ZHAO Xin-bin, NI Min, TAO Xia. Progress on the multiple pharmacological activity and mechanism of statins[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(1): 19-21. doi: 10.3969/j.issn.1006-0111.2013.01.005
Citation: ZHAO Xin-bin, NI Min, TAO Xia. Progress on the multiple pharmacological activity and mechanism of statins[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(1): 19-21. doi: 10.3969/j.issn.1006-0111.2013.01.005
shu

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