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拉曼光谱法在假药快检中的研究进展

柳艳 尹利辉 陆峰

柳艳, 尹利辉, 陆峰. 拉曼光谱法在假药快检中的研究进展[J]. 药学实践与服务, 2012, 30(6): 401-404,446. doi: 10.3969/j.issn.1006-0111.2012.06.001
引用本文: 柳艳, 尹利辉, 陆峰. 拉曼光谱法在假药快检中的研究进展[J]. 药学实践与服务, 2012, 30(6): 401-404,446. doi: 10.3969/j.issn.1006-0111.2012.06.001
LIU Yan, YIN Li-hui, LU Feng. Progress of Raman spectroscopy in fast detection of counterfeit drugs[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(6): 401-404,446. doi: 10.3969/j.issn.1006-0111.2012.06.001
Citation: LIU Yan, YIN Li-hui, LU Feng. Progress of Raman spectroscopy in fast detection of counterfeit drugs[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(6): 401-404,446. doi: 10.3969/j.issn.1006-0111.2012.06.001

拉曼光谱法在假药快检中的研究进展

doi: 10.3969/j.issn.1006-0111.2012.06.001
基金项目: 国家科技支撑计划项目(2008BAI55B06);上海市科学技术重点科技攻关项目(11431922502).

Progress of Raman spectroscopy in fast detection of counterfeit drugs

  • 摘要: 假药的存在不仅严重影响了人们的用药安全和有效,而且干扰了正常的商业与社会秩序,对假药的预防和打击已刻不容缓。近年来,拉曼光谱技术因其独特的优势在假药快检中的应用逐渐增加。本文简述了拉曼光谱法用于假药快检的优点,结合对拉曼光谱预处理、定性与鉴别分析方法的概述,对拉曼光谱法在假药快检中的应用进行了综述,并展望了拉曼光谱在假药快检领域的应用前景。
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    [2] Ricci C,Nyadong L,Yang F,et al. Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry[J]. Anal Chim Acta,2008,623(2):178.
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    [7] 翁欣欣,张中湖,尹利辉,等. KPCA-聚类分析法和用便携式拉曼仪快速鉴别降糖药[J]. 光谱学与光谱分析,2010,30(4):984.
    [8] de Veij M,Deneckere A,Vandenabeele P,et al.Detection of counterfeit Viagra with Raman spectroscopy[J]. J Pharm Biomed Anal,2008,46(2):303.
    [9] 冯昕鞋,朱仲良,沈梦洁,等.基于多项式拟合的拉曼光谱基线漂移校正方法[J]. 计算机与应用化学,2009,26(6):759.
    [10] Ricci C,Eliasson C,Macleod NA,et al.Characterization of genuine and fake artesunate anti-malarial tablets using Fourier transform infrared imaging and spatially offset Raman spectroscopy through blister packs[J]. Anal Bioanal Chem,2007,389(5):1525.
    [11] 曹 玲,石蓓佳,吴 莉,等. 常用羧酸类及其衍生物药用辅料的拉曼光谱鉴别[J]. 药物分析杂志,2010(3):484.
    [12] 刘 畅,张中湖,柳 艳,等.拉曼光谱-区段相似度法用于降糖类药物的快速检测[J]. 药学服务与研究,2011,11(3):196.
    [13] 范贤松,张先芬,沈高山.便携式拉曼光谱仪快速鉴别多潘立酮片真伪的研究[J]. 安徽医药,2010,14(12):1501.
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    [15] 柳 艳,张中湖,陆 峰.降糖类药物的拉曼光谱-小模型判别方法研究[J]. 计算机与应用化学,2012,28(11):1433.
    [16] Been F,Roggo Y,Degardin K,et al.Profiling of counterfeit medicines by vibrational spectroscopy[J]. Forensic Sci Int,2011,211(1-3):83.
    [17] Sacre PY,Deconinck E,Saerens L,et al.Detection of counterfeit Viagra by Raman microspectroscopy imaging and multivariate analysis[J]. J Pharm Biomed Anal,2011,56(2):454.
    [18] 陆 峰,吴玉田. 无模型光谱分析策略[J]. 光谱仪器与分析,2009,(1-3):40.
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    [21] 罗 娅,柳 艳,胡茜茜,等. 便携式拉曼光谱仪用于降糖药品快速检测的研究[J]. 药学实践杂志,2011,29(1):35.
    [22] 宋 清,翁欣欣,陆 峰.用于降糖类药物真伪快速检测的3种拉曼光谱处理方法的比较[J]. 第二军医大学学报,2010,31(9):993.
    [23] 曹 玲,王 玉,罗疆南. 显微共聚焦拉曼检测中药中非法添加的化学降糖药[J]. 药物分析杂志,2011,31(3):539.
    [24] Ricci C,Nyadong L,Yang F,et al.Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry[J]. Anal Chim Acta,2008,623(2):178.
    [25] De Veij M,Vandenabeele P,Hall KA,et al.Fast detection and identification of counterfeit antimalarial tablets by Raman spectroscopy[J]. J Raman Spectrosc,2007,38(2):181.
    [26] De Peinder P,Vredenbregt MJ,Visser T,et al.Detection of Lipitor counterfeits:a comparison of NIR and Raman spectroscopy in combination with chemometrics[J]. J Pharm Biomed Anal,2008,47(4-5):688.
    [27] 王玉,曹玲,罗疆南.显微共聚焦拉曼光谱法检测非法添加的化学壮阳药[J]. 中国药学杂志,2011,46(10):789.
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    [30] Degardin K,Roggo Y,Been F,et al.Detection and chemical profiling of medicine counterfeits by Raman spectroscopy and chemometrics[J]. Anal Chim Acta,2011,705(1-2):334.
    [31] Roggo Y,Degardin K,Margot P.Identification of pharmaceutical tablets by Raman spectroscopy and chemometrics[J]. Talanta,2010,81(3):988.
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出版历程
  • 收稿日期:  2012-04-02
  • 修回日期:  2012-06-28

拉曼光谱法在假药快检中的研究进展

doi: 10.3969/j.issn.1006-0111.2012.06.001
    基金项目:  国家科技支撑计划项目(2008BAI55B06);上海市科学技术重点科技攻关项目(11431922502).

摘要: 假药的存在不仅严重影响了人们的用药安全和有效,而且干扰了正常的商业与社会秩序,对假药的预防和打击已刻不容缓。近年来,拉曼光谱技术因其独特的优势在假药快检中的应用逐渐增加。本文简述了拉曼光谱法用于假药快检的优点,结合对拉曼光谱预处理、定性与鉴别分析方法的概述,对拉曼光谱法在假药快检中的应用进行了综述,并展望了拉曼光谱在假药快检领域的应用前景。

English Abstract

柳艳, 尹利辉, 陆峰. 拉曼光谱法在假药快检中的研究进展[J]. 药学实践与服务, 2012, 30(6): 401-404,446. doi: 10.3969/j.issn.1006-0111.2012.06.001
引用本文: 柳艳, 尹利辉, 陆峰. 拉曼光谱法在假药快检中的研究进展[J]. 药学实践与服务, 2012, 30(6): 401-404,446. doi: 10.3969/j.issn.1006-0111.2012.06.001
LIU Yan, YIN Li-hui, LU Feng. Progress of Raman spectroscopy in fast detection of counterfeit drugs[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(6): 401-404,446. doi: 10.3969/j.issn.1006-0111.2012.06.001
Citation: LIU Yan, YIN Li-hui, LU Feng. Progress of Raman spectroscopy in fast detection of counterfeit drugs[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(6): 401-404,446. doi: 10.3969/j.issn.1006-0111.2012.06.001
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