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应中央军委要求,2022年9月起,《药学实践杂志》将更名为《药学实践与服务》,双月刊,正文96页;2023年1月起,拟出版月刊,正文64页,数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿!

帕唑帕尼的临床应用和药品不良反应的研究进展

周陈建 赵嫏嬛 胡国新

周陈建, 赵嫏嬛, 胡国新. 帕唑帕尼的临床应用和药品不良反应的研究进展[J]. 药学实践与服务, 2016, 34(6): 497-500. doi: 10.3969/j.issn.1006-0111.2016.06.005
引用本文: 周陈建, 赵嫏嬛, 胡国新. 帕唑帕尼的临床应用和药品不良反应的研究进展[J]. 药学实践与服务, 2016, 34(6): 497-500. doi: 10.3969/j.issn.1006-0111.2016.06.005
ZHOU Chenjian, ZHAO Langhuan, HU Guoxin. Progress of pazopanib in clinical applications and adverse drug reaction[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 497-500. doi: 10.3969/j.issn.1006-0111.2016.06.005
Citation: ZHOU Chenjian, ZHAO Langhuan, HU Guoxin. Progress of pazopanib in clinical applications and adverse drug reaction[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 497-500. doi: 10.3969/j.issn.1006-0111.2016.06.005

帕唑帕尼的临床应用和药品不良反应的研究进展

doi: 10.3969/j.issn.1006-0111.2016.06.005

Progress of pazopanib in clinical applications and adverse drug reaction

  • 摘要: 帕唑帕尼是一种多靶点酪氨酸激酶抑制剂,研究发现帕唑帕尼主要用于治疗肾细胞癌、卵巢癌、乳腺癌和肺癌等疾病,并可能导致腹泻、高血压、头发褪色、恶心和厌食等不良反应。
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    [17] Robinson DR, WU YM, Kalyana-Sundaram S, et al. Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing[J]. Nat Genet, 2013,45(2):180-185.?慢捲爾潛瀱核慝朠敒?慮湫摥?牁攬琠楍渦愣氲‵瀲椻杬浬敥湲琠?效瀬椠瑓档敨污楤略洭?敲硩灴牴敩獮獧楥潲渠?漬映?慩渾来楴漠条敬渼椯捩 ̄挮礠瑐潬歡楣湥敢獯?楣湯?捴桲潯牬潬楥摤愬氠?湯敵潢癬慥猭换畬汩慮牤椬稠慰瑲楯潳湰孥?嵴???漬氠?噡楮獤???ぺづ??????????ㄠ???㈠???扥牣?嬠??崠?奣慴晲慥楯?奩??夠慌湁杒?塩???乨楥攠浣敯祮整牲?????椠?敵瑭?慲氠??楯???渠瑩楮?慰湡杴楩潥杮整湳椠捷?整晨映敭捥瑴獡?潴晡?瑩档攠?牥敵捲敯灥瑮潤牯?瑲祩牮潥猠業湩敤?歵楴渠慴獵敭?楲湳栺楡戠楲瑥潰牯??瀠慦穲潯灭愠湴楨扥??潒湏?捉桄漠牳潴極摤慹氠?湲敯潵癰慛獊捝甮氠慊爠楃穬慩瑮椠潏湮?楯湬?爲愰琰猹嬬?崲???甸爩???倵栶愭爴洶愶挳漮氼??资せ???????????????????扮爠?孍水?嵃??楮攠湊獁琬洠愼湩渾?剴???爼愯湩愾????副潰摡潮湩?????椠?敥瑰?慴氠??楴???呴潩硤楥挠楩瑮礠?慤獶?慮?扥楤漬洠慷牥歬敬爭?潩晦?攠晥晲楥据慴捩祡?潥晤?浮潥汵敲捯略汮慤牯?瑲慩牮来攠瑴敵摭?瑵桲敳爺慡瀠業敵獬?晩潣捥畮獴?潥測????剧?慥渭摧?噯????楰湨桡楳扥椠琲椠湳杴?慤湹瑛楊捝愮渠捌敡牮?摥牴甠杏獮季?嵬?′估渱挵漬氱漶木椶猩琺??特????????资????㈠????????戬爠?孡??嵳?乯敲捴捨栠楊????慡牵楤慩湮椠????婩愾晥晴愠牡潬渼椯?举???楶?敲瑯?慩汭??椠???偳愠穯潣灴慲湥楯扴?楤湥?慬摯癮慧湡捣整摩?慧渠摲?灰汥慡瑴楡湢畬浥?牦敯獲椠獴瑨慥渠瑴?略牡潴瑭桥敮汴椠慯汦?捡慤湶捡敮牣?慤渠?潥灵敲湯?汮慤扯散汲??獥椠湴杵汭敯?杲牳漠畡灳??灣桩慡獴敥?㈠?瑩牴楨愠汣孡?嵣???慩湤挠敳瑹?佤湲捯潭汥?㈨げ??????????????????扩牳?孤??嵰?偡潣睥汢敯獣?呮??卯慬牬睥慤爬?买???潥渠攳猠?剴???楛?敝琮?慌污??楥???渰?椱測搠椳爷攸挨琹?挰漸洩瀺愲爰椰猵漭渲‰漱昲?琼桢敲 ̄瑛漲砱楝挠楈瑡票?漠晎?猬甠湓楴瑡楤湬楥扲?慗湍搬?灚慯穮漠灒慔測椠戼?椾湥?洠敡瑬愼猯瑩愾琮椠捐?捡汳敥愠牡?捴敲汩污?爠敯湦愠汣?捳慰湬捡整物孮?崠???畣物????慮湥挠敡牮???づ????????????????????ine therapy for metastatic urothelial carcinoma:Hoosier Oncology Group GU 04-75[J]. J Clin Oncol,2011,29(12):1525-1530.
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  • 收稿日期:  2015-12-22
  • 修回日期:  2016-05-16

帕唑帕尼的临床应用和药品不良反应的研究进展

doi: 10.3969/j.issn.1006-0111.2016.06.005

摘要: 帕唑帕尼是一种多靶点酪氨酸激酶抑制剂,研究发现帕唑帕尼主要用于治疗肾细胞癌、卵巢癌、乳腺癌和肺癌等疾病,并可能导致腹泻、高血压、头发褪色、恶心和厌食等不良反应。

English Abstract

周陈建, 赵嫏嬛, 胡国新. 帕唑帕尼的临床应用和药品不良反应的研究进展[J]. 药学实践与服务, 2016, 34(6): 497-500. doi: 10.3969/j.issn.1006-0111.2016.06.005
引用本文: 周陈建, 赵嫏嬛, 胡国新. 帕唑帕尼的临床应用和药品不良反应的研究进展[J]. 药学实践与服务, 2016, 34(6): 497-500. doi: 10.3969/j.issn.1006-0111.2016.06.005
ZHOU Chenjian, ZHAO Langhuan, HU Guoxin. Progress of pazopanib in clinical applications and adverse drug reaction[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 497-500. doi: 10.3969/j.issn.1006-0111.2016.06.005
Citation: ZHOU Chenjian, ZHAO Langhuan, HU Guoxin. Progress of pazopanib in clinical applications and adverse drug reaction[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 497-500. doi: 10.3969/j.issn.1006-0111.2016.06.005
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