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应中央军委要求,2022年9月起,《药学实践杂志》将更名为《药学实践与服务》,双月刊,正文96页;2023年1月起,拟出版月刊,正文64页,数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿!

抗骨质疏松治疗药物研究的新进展

贾文斌 刘超 邹燕

贾文斌, 刘超, 邹燕. 抗骨质疏松治疗药物研究的新进展[J]. 药学实践与服务, 2017, 35(6): 490-494,542. doi: 10.3969/j.issn.1006-0111.2017.06.003
引用本文: 贾文斌, 刘超, 邹燕. 抗骨质疏松治疗药物研究的新进展[J]. 药学实践与服务, 2017, 35(6): 490-494,542. doi: 10.3969/j.issn.1006-0111.2017.06.003
JIA Wenbin, LIU Chao, ZOU Yan. Research progress on drugs in osteoporosis therapy[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 490-494,542. doi: 10.3969/j.issn.1006-0111.2017.06.003
Citation: JIA Wenbin, LIU Chao, ZOU Yan. Research progress on drugs in osteoporosis therapy[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 490-494,542. doi: 10.3969/j.issn.1006-0111.2017.06.003

抗骨质疏松治疗药物研究的新进展

doi: 10.3969/j.issn.1006-0111.2017.06.003

Research progress on drugs in osteoporosis therapy

  • 摘要: 骨质疏松是一种常见的全身性骨代谢疾病,主要表现为骨密度与骨量的下降,从而导致继发性骨折。目前,随着其发病率不断增高,骨质疏松已经成为一个世界范围的健康问题和当前医学的研究热点。骨吸收抑制剂主要作用于破骨细胞,通过抑制破骨细胞分化成熟,减少骨吸收;骨形成促进剂主要作用于成骨细胞,激活其骨形成功能,并且有重建骨组织的效应;骨矿化物是防治骨质疏松的基础药物,包括钙剂和维生素D;解偶联剂种类较为单一,代表药物为雷尼酸锶。主要对以上四大类抗骨质疏松药物的研究进展进行介绍。
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    [18] 马慧萍,贾正平,葛欣,等.骨质疏松症的药物防治研究现状[J],中国药师, 2004, 7(10):816-818.
    [19] Bhandari KH, Asghar W, Newa M, et al. Evaluation of bone targeting salmon calcitonin analogues in rats developing osteoporosis and adjuvant arthritis[J]. Curr Drug Deliv, 2015, 12(1):98-107.
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    [25] Francis RM, Aspray TJ, Bow
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  • 收稿日期:  2017-08-24
  • 修回日期:  2017-10-16

抗骨质疏松治疗药物研究的新进展

doi: 10.3969/j.issn.1006-0111.2017.06.003

摘要: 骨质疏松是一种常见的全身性骨代谢疾病,主要表现为骨密度与骨量的下降,从而导致继发性骨折。目前,随着其发病率不断增高,骨质疏松已经成为一个世界范围的健康问题和当前医学的研究热点。骨吸收抑制剂主要作用于破骨细胞,通过抑制破骨细胞分化成熟,减少骨吸收;骨形成促进剂主要作用于成骨细胞,激活其骨形成功能,并且有重建骨组织的效应;骨矿化物是防治骨质疏松的基础药物,包括钙剂和维生素D;解偶联剂种类较为单一,代表药物为雷尼酸锶。主要对以上四大类抗骨质疏松药物的研究进展进行介绍。

English Abstract

贾文斌, 刘超, 邹燕. 抗骨质疏松治疗药物研究的新进展[J]. 药学实践与服务, 2017, 35(6): 490-494,542. doi: 10.3969/j.issn.1006-0111.2017.06.003
引用本文: 贾文斌, 刘超, 邹燕. 抗骨质疏松治疗药物研究的新进展[J]. 药学实践与服务, 2017, 35(6): 490-494,542. doi: 10.3969/j.issn.1006-0111.2017.06.003
JIA Wenbin, LIU Chao, ZOU Yan. Research progress on drugs in osteoporosis therapy[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 490-494,542. doi: 10.3969/j.issn.1006-0111.2017.06.003
Citation: JIA Wenbin, LIU Chao, ZOU Yan. Research progress on drugs in osteoporosis therapy[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 490-494,542. doi: 10.3969/j.issn.1006-0111.2017.06.003
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