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应中央军委要求,2022年9月起,《药学实践杂志》将更名为《药学实践与服务》,双月刊,正文96页;2023年1月起,拟出版月刊,正文64页,数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿!

白色念珠菌TOR信号转导通路研究现状

梁华军 阎澜 曹永兵 姜远英 颜天华

梁华军, 阎澜, 曹永兵, 姜远英, 颜天华. 白色念珠菌TOR信号转导通路研究现状[J]. 药学实践与服务, 2014, 32(4): 246-249,287. doi: 10.3969/j.issn.1006-0111.2014.04.002
引用本文: 梁华军, 阎澜, 曹永兵, 姜远英, 颜天华. 白色念珠菌TOR信号转导通路研究现状[J]. 药学实践与服务, 2014, 32(4): 246-249,287. doi: 10.3969/j.issn.1006-0111.2014.04.002
LIANG Huajun, YAN Lan, CAO Yongbing, JIANG Yuanying, YAN Tianhua. Advances in TOR pathway in Candida albicans[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(4): 246-249,287. doi: 10.3969/j.issn.1006-0111.2014.04.002
Citation: LIANG Huajun, YAN Lan, CAO Yongbing, JIANG Yuanying, YAN Tianhua. Advances in TOR pathway in Candida albicans[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(4): 246-249,287. doi: 10.3969/j.issn.1006-0111.2014.04.002

白色念珠菌TOR信号转导通路研究现状

doi: 10.3969/j.issn.1006-0111.2014.04.002
基金项目: 国家973项目(2013CB531602);国家自然科学基金资助项目(31000079);上海市基础研究重点项目(14JC1417500).

Advances in TOR pathway in Candida albicans

  • 摘要: 雷帕霉素靶(target of rapamycin,TOR)蛋白是真核细胞生长的关键调控因子,是一类进化上保守的丝氨酸/苏氨酸(Ser/Thr)蛋白激酶,属于磷脂酰肌醇相关激酶(phosphatidylinositol kinase-related kinases, PIKKs)家族。TOR信号通路通过参与调节翻译的起始和延伸,核糖体生成,蛋白质生物合成,氨基酸转运,以及多种代谢酶的转运而使细胞对外界环境刺激产生应答。在此对人类条件性致病菌白色念珠菌TOR信号通路的研究现状作一综述。
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白色念珠菌TOR信号转导通路研究现状

doi: 10.3969/j.issn.1006-0111.2014.04.002
    基金项目:  国家973项目(2013CB531602);国家自然科学基金资助项目(31000079);上海市基础研究重点项目(14JC1417500).

摘要: 雷帕霉素靶(target of rapamycin,TOR)蛋白是真核细胞生长的关键调控因子,是一类进化上保守的丝氨酸/苏氨酸(Ser/Thr)蛋白激酶,属于磷脂酰肌醇相关激酶(phosphatidylinositol kinase-related kinases, PIKKs)家族。TOR信号通路通过参与调节翻译的起始和延伸,核糖体生成,蛋白质生物合成,氨基酸转运,以及多种代谢酶的转运而使细胞对外界环境刺激产生应答。在此对人类条件性致病菌白色念珠菌TOR信号通路的研究现状作一综述。

English Abstract

梁华军, 阎澜, 曹永兵, 姜远英, 颜天华. 白色念珠菌TOR信号转导通路研究现状[J]. 药学实践与服务, 2014, 32(4): 246-249,287. doi: 10.3969/j.issn.1006-0111.2014.04.002
引用本文: 梁华军, 阎澜, 曹永兵, 姜远英, 颜天华. 白色念珠菌TOR信号转导通路研究现状[J]. 药学实践与服务, 2014, 32(4): 246-249,287. doi: 10.3969/j.issn.1006-0111.2014.04.002
LIANG Huajun, YAN Lan, CAO Yongbing, JIANG Yuanying, YAN Tianhua. Advances in TOR pathway in Candida albicans[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(4): 246-249,287. doi: 10.3969/j.issn.1006-0111.2014.04.002
Citation: LIANG Huajun, YAN Lan, CAO Yongbing, JIANG Yuanying, YAN Tianhua. Advances in TOR pathway in Candida albicans[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(4): 246-249,287. doi: 10.3969/j.issn.1006-0111.2014.04.002
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