复方磺胺甲噁唑片释放度的考察
Inspection on release test of compound sulfamethoxazole tablet
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摘要: 目的 考察复方磺胺甲恶唑片释放度。方法 参照美国药典(ⅩⅫ),采用桨法和双波长分光光度法测定5种不同厂家批次的复方磺胺甲恶唑片释放度。结果 5种不同厂家批次的复方磺胺甲恶唑片释放度有非常显着差异(P<001).结论 有必要增加释放度检查以保证国产复方磺胺甲恶唑质量。Abstract: OBJECTIVE To determine the release rate of compound sulfanethoxazole tablet.METHODS Refering to USP(ⅩⅫ), the release rate of the sample from five domestic plants was determined by dualwavelength spectrophotometry. RESULTS The release rates of the sample from five domestic plants were markedly different(P<0.01). CONCLUTION It's necessary to determine the release rate for ensuring the quality of compound sulfamethoxazole tablet made in our country.
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Key words:
- compound sulfamethoxazole tablets /
- release test
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