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应中央军委要求,2022年9月起,《药学实践杂志》将更名为《药学实践与服务》,双月刊,正文96页;2023年1月起,拟出版月刊,正文64页,数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿!

类风湿性关节炎的治疗药物研究进展

王静 赵庆杰 卓小斌 姜云云 叶光明

王静, 赵庆杰, 卓小斌, 姜云云, 叶光明. 类风湿性关节炎的治疗药物研究进展[J]. 药学实践与服务, 2019, 37(6): 485-490. doi: 10.3969/j.issn.1006-0111.2019.06.002
引用本文: 王静, 赵庆杰, 卓小斌, 姜云云, 叶光明. 类风湿性关节炎的治疗药物研究进展[J]. 药学实践与服务, 2019, 37(6): 485-490. doi: 10.3969/j.issn.1006-0111.2019.06.002
WANG Jing, ZHAO Qinjie, ZHUO Xiaobin, JIANG Yunyun, YE Guangming. Research progress on therapeutic drugs for rheumatoid arthritis[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(6): 485-490. doi: 10.3969/j.issn.1006-0111.2019.06.002
Citation: WANG Jing, ZHAO Qinjie, ZHUO Xiaobin, JIANG Yunyun, YE Guangming. Research progress on therapeutic drugs for rheumatoid arthritis[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(6): 485-490. doi: 10.3969/j.issn.1006-0111.2019.06.002

类风湿性关节炎的治疗药物研究进展

doi: 10.3969/j.issn.1006-0111.2019.06.002

Research progress on therapeutic drugs for rheumatoid arthritis

  • 摘要: 类风湿性关节炎(RA)作为一种常见的自身免疫性疾病,临床表现为关节损伤和滑膜炎症。通过阐述临床RA药物的治疗机制和作用靶点,综述了两大类RA药物,包括小分子合成类RA药物和大分子生物RA药物(肿瘤坏死因子α抑制剂、T、B细胞抑制剂、细胞因子受体抑制剂、靶点RANKL生物制剂以及靶点粒细胞-巨噬细胞集落刺激因子生物制剂),通过结合RA病理机制重点对这两大类药物的治疗机制和作用靶点进行阐明介绍,同时概述了治疗类风湿性关节炎的最新治疗靶点,为类风湿性关节炎患者的治疗提供潜在新方向。
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  • 收稿日期:  2019-06-03
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类风湿性关节炎的治疗药物研究进展

doi: 10.3969/j.issn.1006-0111.2019.06.002

摘要: 类风湿性关节炎(RA)作为一种常见的自身免疫性疾病,临床表现为关节损伤和滑膜炎症。通过阐述临床RA药物的治疗机制和作用靶点,综述了两大类RA药物,包括小分子合成类RA药物和大分子生物RA药物(肿瘤坏死因子α抑制剂、T、B细胞抑制剂、细胞因子受体抑制剂、靶点RANKL生物制剂以及靶点粒细胞-巨噬细胞集落刺激因子生物制剂),通过结合RA病理机制重点对这两大类药物的治疗机制和作用靶点进行阐明介绍,同时概述了治疗类风湿性关节炎的最新治疗靶点,为类风湿性关节炎患者的治疗提供潜在新方向。

English Abstract

王静, 赵庆杰, 卓小斌, 姜云云, 叶光明. 类风湿性关节炎的治疗药物研究进展[J]. 药学实践与服务, 2019, 37(6): 485-490. doi: 10.3969/j.issn.1006-0111.2019.06.002
引用本文: 王静, 赵庆杰, 卓小斌, 姜云云, 叶光明. 类风湿性关节炎的治疗药物研究进展[J]. 药学实践与服务, 2019, 37(6): 485-490. doi: 10.3969/j.issn.1006-0111.2019.06.002
WANG Jing, ZHAO Qinjie, ZHUO Xiaobin, JIANG Yunyun, YE Guangming. Research progress on therapeutic drugs for rheumatoid arthritis[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(6): 485-490. doi: 10.3969/j.issn.1006-0111.2019.06.002
Citation: WANG Jing, ZHAO Qinjie, ZHUO Xiaobin, JIANG Yunyun, YE Guangming. Research progress on therapeutic drugs for rheumatoid arthritis[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(6): 485-490. doi: 10.3969/j.issn.1006-0111.2019.06.002
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