临床药师参与141例感染性疾病会诊的分析与体会

张晋萍; 张海霞; 徐航; 卞晓洁; 杨贤; 方芸

doi:10.3969/j.issn.1006-0111.2017.01.023

临床药师参与141例感染性疾病会诊的分析与体会

doi: 10.3969/j.issn.1006-0111.2017.01.023

南京大学医学院附属鼓楼医院药学部, 江苏南京 210008

Clinical pharmacists involvement in consultation: analysis and experience of 141 cases of infectious disease

Nanjing Drum Tower Hospital Affiliated to Medical College of Nanjing University, Pharmacy Department, Nanjing 210008, China

摘要: 目的从临床药师参与感染性疾病会诊中的案例，探讨药师如何运用专业知识参与临床药物治疗方案的调整，从而融入治疗团队。方法统计、分析2012年8月-2015年3月临床药师参与会诊的141例感染性疾病患者的基本情况、科室分布、会诊目的、病原学检查情况、药师建议采纳情况以及患者治疗结果等。结果 141例会诊病例中，泌尿外科、肝胆外科以及神经外科会诊数量居前三位，构成比分别为26.95%、21.99%及17.73%；会诊目的中，居前三位的有特殊用药会诊、药物治疗方案调整以及药物选择，分别占85.82%、74.62%及59.57%；会诊意见全部被采纳、部分被采纳以及未被采纳者分别为133例、1例及7例，分别占94.33%、0.71%及4.96%。结论通过参与会诊，并在会诊后持续跟进、不断学习、总结提高，临床药师可发挥专业优势，与医师一起为确保患者用药安全、有效贡献力量。
- 临床药师 /
- 感染性疾病 /
- 会诊 /
- 药物治疗
Abstract: Objective To investigate how the clinical pharmacists participate in the regime design and adjustment in the treatment of infectious disease and to show how clinical pharmacists to team with physicians for patient's infection control by contributing their special knowledge. Method From August 2012 to April 2014, 141 patients were consulted by the clinical pharmacists for the infectious diseases. The patient's basic information, ward distribution, consultation purpose, etiology of infections and adoption of the suggestions were analyzed. Results Among 141 consulted cases, most patients belonged to the urology, hepatobiliary surgery and neurosurgery department (accounted for 26.95%, 21.99% and 17.73% respectively). The top three consultation subjects are the use of ‘special use class’ antimicrobials, regime adjustment and medication choice (accounted for 85.82%, 74.62% and 59.57%). 133 suggestions from clinical pharmacists were accepted, 1 was partially adopted and 7 were rejected (accounted for 94.33%, 0.71% and 4.96%). Conclusion The clinical pharmacists play important roles in the treatment of infectious disease by providing the consultations to clinicians. With their special knowledge, clinical pharmacists can make a good contribution to ensure the safe and effective drug therapies.
- clinical pharmacist /
- infectious diseases /
- consultation /
- pharmacotherapy

[1]	陆赛花,吴玮峰,刘秀凤,等.临床药师在呼吸科参与抗菌药物使用的体会[J].中国医院药学杂志,2012,32(8):645-646.
[2]	李雪芹,李云景,卢荣枝,等.临床药师参与317例细菌感染性病例会诊分析[J].中国药物应用与监测,2012,9(3):150-152.
[3]	张波,冯雷,梅丹. 临床药师参与会诊的实践和分析[J].中国医院药学杂志,2014,34(2):148-151.
[4]	Quantrill S, Webbe D. Including pharmacists on consultant-led ward rounds[J]. Clin Med, 2011,11(6):627-628.
[5]	丁伯君,邓艳春,文娟.左乙拉西坦添加治疗难治性癫痫的疗效和安全性分析[J].中国临床神经科学,2011,19(2):189-191,198.
[6]	袁展望,李武平,刘冰,等.预防留置导尿管相关感染研究进展[J]. 中国感染控制杂志,2013,12(5):397-399.
[7]	陈晓华,李武平,刘冰,等.泌尿系统感染现状及防治研究进展[J].解放军护理杂志,2015,32(16):38-42,45.
[8]	Sarmiento JM, Dockrell DH, Schwab TR,et al. Mycophenolate mofetil increases cytomegalovirus invasive organ disease in renal transplant patients[J]. Clin Transplant, 2000,14(2):136-138.
[9]	Kupeli E, Ulubay G, Golak T, et al. Pulmonary complications in renal recipients after transplantation[J]. Transplant Proc,2011,43(2):551-553.
[10]	孙斌,汪泽厚,姚志勇,等. 肾移植术后肺部感染患者免疫抑制剂的调整[J]. 空军总医院学报,2007,23(3):152-156.
[11]	Nose K, Oki T, Banno E, et al. Cytomegalovirus infection after prophylactic valganciclovir therapy postkidney transplantation:case reports[J]. Transplant Proc,2012,44(1):296-298.
[12]	Goto N, Oka S. Pneumocystis jirovecii pneumonia in kidney transplantation[J]. Transpl Infect Dis,2011,13(6):551-558.
[13]	Alangaden GJ, Thyagarajan R, Gruber SA, et al. Infectious complications after kidney transplantation:current epidemiology and associated risk factors[J]. Clin Transplant, 2006,20(4):401-409.
[14]	Dantas SR, Kuboyama RH, Mazzali M, et al. Nosocomial infections in renal transplant patients:risk factors and treatment implications associated with urinary tract and surgical site infections[J]. J Hosp Infect, 2006, 63(2):117-123.
[15]	Rubin RH, Wolfson JS, Cosimi AB, et al. Infection in the renal transplant recipient[J]. Am J Med,1981,70(2):405-411.
[16]	郭代红,陈超,李罄,等. 6所医院414例利奈唑胺相关性血小板减少集中监测研究[J].药物流行病学杂志,2013,22(3):109-113.
[17]	Chen C, Guo DH, Cao XT, et al. Risk factors for thrombocytopenia in adult Chinese receiving linezolid therapy[J]. Curr Ther Res Clin Exp, 2012,73(6):195-206.
[18]	Matsumoto K, Takeda Y, Takeshita A, et al. Renal function as a predictor of linezolid-induced thrombocytopenia[J].Int J Antimicrob Agents,2009,36(2):179-181.
[19]	Matsumoto K, Takeshita A, Ikawa K, et al. Higher linezolid exposure and higher frequency of thrombocytopenia in patients with renal dysfunction[J]. Int J Antimrcro Agents,2009,33(1):98-99.
[20]	Brier ME, Stalker DJ, Aronoff GR, et al. Pharmacokinetics of linezolid in subjects with renal dysfunction[J]. Antimicrob Agents Chemother, 2003,47(9):2775-2780.

[1]	迟文雅, 袁艳, 李伟林, 吴茼妤, 俞媛. 负载骨髓间充质干细胞/白藜芦醇脂质体的水凝胶支架用于创伤性脑损伤治疗 . 药学实践与服务, 2024, 42(): 1-8. doi: 10.12206/j.issn.2097-2024.202406034
[2]	刘丽艳, 余小翠, 孙传铎. 纳武利尤单抗治疗非小细胞肺癌有效性及安全性的Meta分析 . 药学实践与服务, 2024, 42(10): 451-456. doi: 10.12206/j.issn.2097-2024.202310044
[3]	丁华敏, 郭羽晨, 秦春霞, 宋志兵, 孙莉莉. 消风止痒颗粒通过降低白三烯水平对小鼠特应性皮炎急性瘙痒的治疗作用研究 . 药学实践与服务, 2024, 42(5): 211-216. doi: 10.12206/j.issn.2097-2024.202306031
[4]	唐淑慧, 凤美娟, 薛智霞, 鲁桂华. 帕博利珠单抗治疗所致免疫相关不良反应与中医体质的相关性研究 . 药学实践与服务, 2024, 42(5): 217-222. doi: 10.12206/j.issn.2097-2024.202311029
[5]	景凯, 杨慈荣, 张圳, 臧艺蓓, 刘霞. 黄芪甲苷衍生物治疗慢性心力衰竭小鼠的药效评价及作用机制研究 . 药学实践与服务, 2024, 42(5): 190-197. doi: 10.12206/j.issn.2097-2024.202310004
[6]	尹小娟, 台力丽, 肖俊峰, 季波. 铜绿假单胞菌合并按蚊伊丽莎白菌肺部感染的病例分析 . 药学实践与服务, 2024, 42(5): 223-226. doi: 10.12206/j.issn.2097-2024.202310042
[7]	张艺昕, 关欣怡, 王博宁, 闻俊, 洪战英. 二氢吡啶类钙离子拮抗药物手性分析及其立体选择性药动学研究进展 . 药学实践与服务, 2024, 42(8): 319-324. doi: 10.12206/j.issn.2097-2024.202308062
[8]	陈莹, 许子华, 胡北, 崔亚玲, 高欢, 吴琼. 通便灵胶囊治疗便秘的药效与机制研究 . 药学实践与服务, 2024, 42(): 1-7. doi: 10.12206/j.issn.2097-2024.202404008
[9]	黄韵, 张正银, 金英, 郑怡菁, 李铁军, 孙莉莉. 耐碳青霉烯类肺炎克雷伯菌及大肠埃希菌临床分离株耐药性及耐药基因分析 . 药学实践与服务, 2024, 42(10): 445-450. doi: 10.12206/j.issn.2097-2024.202309059
[10]	马兹芬, 许维恒, 金煜翔, 薛磊. 食管癌的靶向治疗与免疫治疗研究进展 . 药学实践与服务, 2024, 42(6): 231-237. doi: 10.12206/j.issn.2097-2024.202306008
[11]	夏哲炜, 曾垣烨, 朱海菲, 李育, 陈啸飞. 核磁共振磷谱法测定磷酸氢钙咀嚼片中药物含量 . 药学实践与服务, 2024, 42(9): 399-401, 406. doi: 10.12206/j.issn.2097-2024.202404063
[12]	陈怡君, 王卓, 何苗, 张宇, 田泾. 泌尿系统碎石术抗菌药物预防使用合理管控实践 . 药学实践与服务, 2024, 42(): 1-5. doi: 10.12206/j.issn.2097-2024.202402034
[13]	张元林, 宋凯, 孙蕊, 舒飞, 舒丽芯, 杨樟卫. 基于真实世界数据的药物利用研究综述 . 药学实践与服务, 2024, 42(6): 238-243. doi: 10.12206/j.issn.2097-2024.202312010
[14]	杨凤艳, 张月, 陈恩贤, 缪雪蓉, 魏凯. 瑞马唑仑临床应用研究进展 . 药学实践与服务, 2024, 42(9): 365-374. doi: 10.12206/j.issn.2097-2024.202405026
[15]	宋雨桐, 夏德润, 顾珩, 唐少文, 易洪刚, 沃红梅. 帕博利珠单抗与铂类化疗方案在晚期非小细胞肺癌一线治疗中的药物经济学评价 . 药学实践与服务, 2024, 42(8): 334-340. doi: 10.12206/j.issn.2097-2024.202303023
[16]	陈春娟, 郑志新, 李骊. 平喘方联合孟鲁司特钠治疗儿童支气管哮喘患者的临床疗效观察 . 药学实践与服务, 2024, 42(): 1-5. doi: 10.12206/j.issn.2097-2024.202405035
[17]	张晶晶, 索丽娜, 郑兆红. 89例细菌性肝脓肿的临床特征及抗感染治疗分析 . 药学实践与服务, 2024, 42(6): 267-272. doi: 10.12206/j.issn.2097-2024.202302039
[18]	宋泽成, 陈林林, 鲁仁义, 刘梦肖, 王彦. 脓毒症治疗的研究进展 . 药学实践与服务, 2024, 42(11): 1-5. doi: 10.12206/j.issn.2097-2024.202405059
[19]	孙丹倪, 黄勇, 张嘉宝, 王培. 代谢相关脂肪性肝病的无创诊断与药物治疗的新观点和未来展望 . 药学实践与服务, 2024, 42(10): 411-418. doi: 10.12206/j.issn.2097-2024.202403049
[20]	崔晓林, 付晓菲, 杜艳红, 刘娟, 朱茜, 刘子祺. 临床药师参与吉瑞替尼致QTc间期延长的病例分析 . 药学实践与服务, 2024, 42(6): 263-266. doi: 10.12206/j.issn.2097-2024.202309050

点击查看大图

计量

文章访问数: 3109
HTML全文浏览量: 293
PDF下载量: 598
被引次数: 0

姓名
邮箱
手机号码
标题
留言内容
验证码

留言板

临床药师参与141例感染性疾病会诊的分析与体会

doi: 10.3969/j.issn.1006-0111.2017.01.023

Clinical pharmacists involvement in consultation: analysis and experience of 141 cases of infectious disease

计量

临床药师参与141例感染性疾病会诊的分析与体会

doi: 10.3969/j.issn.1006-0111.2017.01.023

南京大学医学院附属鼓楼医院药学部, 江苏南京 210008

English Abstract

Clinical pharmacists involvement in consultation: analysis and experience of 141 cases of infectious disease

Nanjing Drum Tower Hospital Affiliated to Medical College of Nanjing University, Pharmacy Department, Nanjing 210008, China

全文HTML

目录

留言板

临床药师参与141例感染性疾病会诊的分析与体会

doi: 10.3969/j.issn.1006-0111.2017.01.023

Clinical pharmacists involvement in consultation: analysis and experience of 141 cases of infectious disease

计量

出版历程

临床药师参与141例感染性疾病会诊的分析与体会

doi: 10.3969/j.issn.1006-0111.2017.01.023

南京大学医学院附属鼓楼医院药学部, 江苏 南京 210008

English Abstract

Clinical pharmacists involvement in consultation: analysis and experience of 141 cases of infectious disease

Nanjing Drum Tower Hospital Affiliated to Medical College of Nanjing University, Pharmacy Department, Nanjing 210008, China

全文HTML

目录

南京大学医学院附属鼓楼医院药学部, 江苏南京 210008