内分泌科临床药师参与1例糖尿病合并高催乳素血症患者的治疗实践

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

x 关闭永久关闭

应中央军委要求，2022年9月起，《药学实践杂志》将更名为《药学实践与服务》，双月刊，正文96页；2023年1月起，拟出版月刊，正文64页，数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿！

内分泌科临床药师参与1例糖尿病合并高催乳素血症患者的治疗实践

文章导航 > 药学实践与服务 > 2015 > 33(2): 167-170

王涛, 邓昂. 内分泌科临床药师参与1例糖尿病合并高催乳素血症患者的治疗实践[J]. 药学实践与服务, 2015, 33(2): 167-170. doi: 10.3969/j.issn.1006-0111.2015.02.020

引用本文:

王涛, 邓昂. 内分泌科临床药师参与1例糖尿病合并高催乳素血症患者的治疗实践[J]. 药学实践与服务, 2015, 33(2): 167-170. doi: 10.3969/j.issn.1006-0111.2015.02.020

WANG Tao, DENG Ang. Clinical practice of an endocrinology clinical pharmacists participating in the treatment of a patient with diabetes and hyperprolactinemia[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 167-170. doi: 10.3969/j.issn.1006-0111.2015.02.020

Citation:

WANG Tao, DENG Ang. Clinical practice of an endocrinology clinical pharmacists participating in the treatment of a patient with diabetes and hyperprolactinemia[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 167-170. doi: 10.3969/j.issn.1006-0111.2015.02.020

内分泌科临床药师参与1例糖尿病合并高催乳素血症患者的治疗实践

doi: 10.3969/j.issn.1006-0111.2015.02.020

王涛¹,
邓昂^2,

1.
徐州医学院附属医院药学部, 江苏徐州 221006
2.
北京中日友好医院药学部, 北京 100029

Clinical practice of an endocrinology clinical pharmacists participating in the treatment of a patient with diabetes and hyperprolactinemia

WANG Tao¹,
DENG Ang^2
,

1.
Department of Pharmacy, Affiliated Hospital of Xuzhou Medical College, Xuzhou 221006, China
2.
Department of Pharmacy, China-Japan Friendship Hospital, Beijing 100029, China

摘要: 目的探讨内分泌科临床药师参与临床药物治疗的工作模式。方法临床药师通过参与1例糖尿病合并高催乳素血症患者的治疗,分析患者血糖控制不佳及高催乳素血症的原因,提出治疗方案。结果长期服用抗精神病药物可能是患者血糖控制不佳的原因之一。高催乳素血症可能与患者长期服用抗精神病药帕潘立酮缓释片有关,建议患者转诊精神科,选用无升高催乳素作用的抗精神病药物治疗。结论临床药师积极参与临床治疗,能有效提高患者用药的合理性和依从性。
- 临床药师 /
- 糖尿病 /
- 高催乳素血症 /
- 抗精神病药物
Abstract: Objective To explore the working pattern for endocrinology clinical pharmacists participating in clinical drug treatment. Methods By participating in the treatment for a patient with diabetes and hyperprolactinemia and analyzing the causes of poor glycemic control and hyperprolactinemia, clinical pharmacists proposed therapeutic regimen. Results The long-term psychotropic medication may be one of the reasons why blood glucose of the patient was unsatisfactorily controlled. The patient with hyperprolactinemia may be associated with her longstanding use of paliperidone. The patient was recommended to consult a psychiatrist and switch to an alternative medication which does not cause hyperprolactinemia. Conclusion The active participation of clinical pharmacists during clinical drug therapy could improve the medication rationality and compliance of patients with drugs.
- clinical pharmacist /
- diabetes /
- hyperprolactinemia /
- antipsychotic drug

[1]	黎燕, 罗维肖. 非典型抗精神病药与糖尿病关系的研究[J]. 临床精神医学杂志, 2002, 12(5):299-300.
[2]	林琳, 瞿发林. 抗精神病药所致高催乳素血症的防治进展[J]. 实用药物与临床, 2010, 13(4):290-292.
[3]	牟晓东, 张志. 抗精神病药物治疗与血糖调节紊乱[J]. 国外医学精神病学分册, 2004, 31(2):86-88.
[4]	娄素琴, 杨广声, 钱东丽. 抗精神病药物引起血糖升高135例[J]. 医药导报, 2006, 25(10):1009.
[5]	Holt RI, Peveler RC. Association between antipsychotic drugs and diabetes[J]. Diabetes Obes Metab, 2006, 8(2):125-135.
[6]	Allison DB, Casey DE. Antipsychotic-induced weight gain: a review of the literature[J]. J Clin Psychiatr, 2001, 62 (Suppl 7): 22-31.
[7]	Lu CH, Yan YH. Risperidone-associated newly diagnosed diabetes and fatal diabetes ketoacidosis in a young schizophrenic patient[J]. Diabetes Res Clin Pract, 2009, 83(2):e66-67.
[8]	Bostwick JR, Guthrie SK, Ellingrod VL. Antipsychotic-induced hyperprolactinemia[J]. Pharmacotherapy, 2009, 29(1) :64-73.
[9]	Kapur S, Langlois X, Vinken P, et al. The differential effects of atypical antipsychotics on prolactin elevation are explained by their differential blood-brain disposition: a pharmacological analysis in rats[J]. J Pharmacol Exp Ther, 2002, 302(3):1129-1134.
[10]	Staller J. The effect of long-term antipsychotic treatment on prolactin[J]. J Child Adolesc Psychopharmacol, 2006, 16(3):317-326.
[11]	Knegtering R, Baselmans P, Castelein S, et al. Predominant role of the 9-Hydroxy metabolite of risperidone in elevating blood prolactin levels[J]. Am J Psychiatr, 2005, 162(5):1010-1012.
[12]	Melkersson KI. Prolactin elevation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite[J]. Hum Psychopharmacol, 2006, 21(8): 529-532.
[13]	Citrome L. Paliperidone: quo vadis?[J]. Int J Clin Pract, 2007, 61(4):653-662.
[14]	Meltzer HY, Bobo WV, Nuamah IF, et al. Efficacy and tolerability of oral paliperidone extended-release tablets in the treatment of acute schizophrenia: pooled data from three 6-week, placebo-controlled studies[J]. J Clin Psychiatr, 2008, 69(5): 817-829.
[15]	Einarson TR,Hemels ME,Nuamah I,et al.An analysis of potentially prolactin-related adverse events and abnormal prolactin values in randomized clinical trials with paliperidone palmitate[J].Ann Pharmacother,2012,46(10):1322-1330.
[16]	Molitch ME. Drugs and prolactin[J]. Pituitary, 2008, 11(2): 209-218.
[17]	Bankowski BJ, Zacur HA. Dopamine agonist therapy for hyperprolactinemia[J]. Clin Obstet Gynecol, 2003, 46 (2):349-362.
[18]	郭金宏,曹长安. 溴隐亭治疗抗精神病药物致高泌乳素血症的临床研究[J]. 神经疾病与精神卫生, 2003, 3(3) : 244.
[19]	Lee MS, Song HC, An H, et al. Effect of bromocriptine on antipsychotic drug-induced hyperprolactinemia: eight-week randomized, single-blind, placebo-controlled, multicenter study[J]. Psychiatr Clin Neurosci, 2010, 64(1):19-27.
[20]	Rocha FL, Hara C, Ramos MG. Using aripiprazole to attenuate paliperidone-induced hyperprolactinemia[J]. Prog Neuropsychopharmacol Biol Psychiatr, 2010, 34(6):1153-1154.
[21]	魏桂林, 徐小薇, 李大魁. 药物与高催乳素血症[J]. 药物不良反应杂志, 2000, 2(2):73-75.

[1]	宋雨桐, 夏德润, 顾珩, 唐少文, 易洪刚, 沃红梅. 帕博利珠单抗与铂类化疗方案在晚期非小细胞肺癌一线治疗中的药物经济学评价 . 药学实践与服务, 2024, 42(8): 334-340. doi: 10.12206/j.issn.2097-2024.202303023
[2]	张艺昕, 关欣怡, 王博宁, 闻俊, 洪战英. 二氢吡啶类钙离子拮抗药物手性分析及其立体选择性药动学研究进展 . 药学实践与服务, 2024, 42(8): 319-324. doi: 10.12206/j.issn.2097-2024.202308062
[3]	孙丹倪, 黄勇, 张嘉宝, 王培. 代谢相关脂肪性肝病的无创诊断与药物治疗的新观点和未来展望 . 药学实践与服务, 2024, 42(10): 411-418. doi: 10.12206/j.issn.2097-2024.202403049
[4]	夏哲炜, 曾垣烨, 朱海菲, 李育, 陈啸飞. 核磁共振磷谱法测定磷酸氢钙咀嚼片中药物含量 . 药学实践与服务, 2024, 42(9): 399-401, 406. doi: 10.12206/j.issn.2097-2024.202404063
[5]	陈怡君, 王卓, 何苗, 张宇, 田泾. 泌尿系统碎石术抗菌药物预防使用合理管控实践 . 药学实践与服务, 2024, 42(): 1-5. doi: 10.12206/j.issn.2097-2024.202402034
[6]	张元林, 宋凯, 孙蕊, 舒飞, 舒丽芯, 杨樟卫. 基于真实世界数据的药物利用研究综述 . 药学实践与服务, 2024, 42(6): 238-243. doi: 10.12206/j.issn.2097-2024.202312010
[7]	黄韵, 张正银, 金英, 郑怡菁, 李铁军, 孙莉莉. 耐碳青霉烯类肺炎克雷伯菌及大肠埃希菌临床分离株耐药性及耐药基因分析 . 药学实践与服务, 2024, 42(10): 445-450. doi: 10.12206/j.issn.2097-2024.202309059
[8]	陈春娟, 郑志新, 李骊. 平喘方联合孟鲁司特钠治疗儿童支气管哮喘患者的临床疗效观察 . 药学实践与服务, 2024, 42(): 1-5. doi: 10.12206/j.issn.2097-2024.202405035
[9]	张晶晶, 索丽娜, 郑兆红. 89例细菌性肝脓肿的临床特征及抗感染治疗分析 . 药学实践与服务, 2024, 42(6): 267-272. doi: 10.12206/j.issn.2097-2024.202302039
[10]	杨凤艳, 张月, 陈恩贤, 缪雪蓉, 魏凯. 瑞马唑仑临床应用研究进展 . 药学实践与服务, 2024, 42(9): 365-374. doi: 10.12206/j.issn.2097-2024.202405026
[11]	毛智毅, 王筱燕, 陈晓颖, 汤逸斐. 度拉糖肽联合二甲双胍对肥胖型2型糖尿病患者机体代谢、体脂成分及血清脂肪因子的影响 . 药学实践与服务, 2024, 42(7): 305-309. doi: 10.12206/j.issn.2097-2024.202305032
[12]	陈静, 何瑞华, 翁月, 徐熠, 刘静, 黄瑾. 基于网络药理学和分子对接技术探究定清片活性成分治疗白血病的作用机制 . 药学实践与服务, 2024, 42(): 1-8. doi: 10.12206/j.issn.2097-2024.202401073
[13]	刘依秦, 王超群, 邱娇娜. 胆宁片预处理在糖尿病患者结肠镜检查前的应用效果分析 . 药学实践与服务, 2024, 42(9): 407-410. doi: 10.12206/j.issn.2097-2024.202407037
[14]	崔晓林, 付晓菲, 杜艳红, 刘娟, 朱茜, 刘子祺. 临床药师参与吉瑞替尼致QTc间期延长的病例分析 . 药学实践与服务, 2024, 42(6): 263-266. doi: 10.12206/j.issn.2097-2024.202309050
[15]	徐飞, 陈瑾, 鲁育含, 李志勇. 肠道菌群参与糖尿病肾病的机制研究进展 . 药学实践与服务, 2024, 42(5): 181-184, 197. doi: 10.12206/j.issn.2097-2024.202312023

WeChat

点击查看大图

计量

文章访问数: 2504
HTML全文浏览量: 269
PDF下载量: 421
被引次数: 0

内分泌科临床药师参与1例糖尿病合并高催乳素血症患者的治疗实践

doi: 10.3969/j.issn.1006-0111.2015.02.020

王涛¹,
邓昂^{2
,}

1. 徐州医学院附属医院药学部, 江苏徐州 221006

2. 北京中日友好医院药学部, 北京 100029

收稿日期: 2014-02-17
修回日期: 2014-09-22

关键词:

高催乳素血症 /

抗精神病药物

摘要: 目的探讨内分泌科临床药师参与临床药物治疗的工作模式。方法临床药师通过参与1例糖尿病合并高催乳素血症患者的治疗,分析患者血糖控制不佳及高催乳素血症的原因,提出治疗方案。结果长期服用抗精神病药物可能是患者血糖控制不佳的原因之一。高催乳素血症可能与患者长期服用抗精神病药帕潘立酮缓释片有关,建议患者转诊精神科,选用无升高催乳素作用的抗精神病药物治疗。结论临床药师积极参与临床治疗,能有效提高患者用药的合理性和依从性。

English Abstract

王涛, 邓昂. 内分泌科临床药师参与1例糖尿病合并高催乳素血症患者的治疗实践[J]. 药学实践与服务, 2015, 33(2): 167-170. doi: 10.3969/j.issn.1006-0111.2015.02.020

引用本文:

王涛, 邓昂. 内分泌科临床药师参与1例糖尿病合并高催乳素血症患者的治疗实践[J]. 药学实践与服务, 2015, 33(2): 167-170. doi: 10.3969/j.issn.1006-0111.2015.02.020

WANG Tao, DENG Ang. Clinical practice of an endocrinology clinical pharmacists participating in the treatment of a patient with diabetes and hyperprolactinemia[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 167-170. doi: 10.3969/j.issn.1006-0111.2015.02.020

Citation:

WANG Tao, DENG Ang. Clinical practice of an endocrinology clinical pharmacists participating in the treatment of a patient with diabetes and hyperprolactinemia[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 167-170. doi: 10.3969/j.issn.1006-0111.2015.02.020

全文HTML

参考文献 (21)

/

下载: 全尺寸图片幻灯片

分享

用微信扫码二维码

分享至好友和朋友圈

返回

版权所有：《药学实践与服务》编辑委员会

主管、主办: 中国人民解放军海军军医大学地址: 上海市杨浦区国和路325号邮政编码: 200433

电话: （021）81871324,81871397 E-mail: yxsjzzs@163.com

网站备案号沪ICP备05003363号-1

本系统由北京仁和汇智信息技术有限公司开发