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二氢黄酮类化合物的合成研究进展

梁海 向卓 张学辉 吴久鸿

梁海, 向卓, 张学辉, 吴久鸿. 二氢黄酮类化合物的合成研究进展[J]. 药学实践与服务, 2015, 33(2): 97-101,130. doi: 10.3969/j.issn.1006-0111.2015.02.001
引用本文: 梁海, 向卓, 张学辉, 吴久鸿. 二氢黄酮类化合物的合成研究进展[J]. 药学实践与服务, 2015, 33(2): 97-101,130. doi: 10.3969/j.issn.1006-0111.2015.02.001
LIANG Hai, XIANG Zhuo, ZHANG Xuehui, WU Jiuhong. Reviews on flavanone compounds synthesis research[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 97-101,130. doi: 10.3969/j.issn.1006-0111.2015.02.001
Citation: LIANG Hai, XIANG Zhuo, ZHANG Xuehui, WU Jiuhong. Reviews on flavanone compounds synthesis research[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 97-101,130. doi: 10.3969/j.issn.1006-0111.2015.02.001

二氢黄酮类化合物的合成研究进展

doi: 10.3969/j.issn.1006-0111.2015.02.001
基金项目: 国家自然科学基金项目(No.81072546)

Reviews on flavanone compounds synthesis research

  • 摘要: 综述二氢黄酮类化合物的合成研究进展, 总结已报道的各种类型的二氢黄酮合成方法, 为二氢黄酮类新药研发提供方法学支持。合成方法包括:查尔酮环合、Friedel-Crafts反应、Knoevenagel缩合和Hoesch单酰基化反应, 以及二氢黄酮的不对称合成, 并简要介绍无溶剂合成二氢黄酮等"绿色"化学方法。
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    [6] Zhou ZL, Fu CY. A new flavanone and other constituents from the rhizomes of Cyperus rotundus and their antioxidant activities[J]. Chem Nat Compd, 2013, 48(6): 963-965.
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    [9] 郭冬冬, 杨金会, 梁西周, 等. 两种天然异戊烯基黄烷酮的全合成[J]. 合成化学, 2013, 21(5): 550-553.
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    [20] Choudary BM, Ranganath KVS, Yadav J, et al. Synthesis of flavanones using nanocrystalline MgO[J]. Tetrahedron Lett, 2005, 46(8): 1369-1371.
    [21] Saravanamurugan S, Palanichamy M, Arabmdoo B, et al. Solvent free synthesis of chalcone and flavanone over zinc oxide supported metal oxide catalysts[J]. Catal Commun, 2005, 6(6): 399-403.
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  • 收稿日期:  2013-11-28
  • 修回日期:  2014-04-21

二氢黄酮类化合物的合成研究进展

doi: 10.3969/j.issn.1006-0111.2015.02.001
    基金项目:  国家自然科学基金项目(No.81072546)

摘要: 综述二氢黄酮类化合物的合成研究进展, 总结已报道的各种类型的二氢黄酮合成方法, 为二氢黄酮类新药研发提供方法学支持。合成方法包括:查尔酮环合、Friedel-Crafts反应、Knoevenagel缩合和Hoesch单酰基化反应, 以及二氢黄酮的不对称合成, 并简要介绍无溶剂合成二氢黄酮等"绿色"化学方法。

English Abstract

梁海, 向卓, 张学辉, 吴久鸿. 二氢黄酮类化合物的合成研究进展[J]. 药学实践与服务, 2015, 33(2): 97-101,130. doi: 10.3969/j.issn.1006-0111.2015.02.001
引用本文: 梁海, 向卓, 张学辉, 吴久鸿. 二氢黄酮类化合物的合成研究进展[J]. 药学实践与服务, 2015, 33(2): 97-101,130. doi: 10.3969/j.issn.1006-0111.2015.02.001
LIANG Hai, XIANG Zhuo, ZHANG Xuehui, WU Jiuhong. Reviews on flavanone compounds synthesis research[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 97-101,130. doi: 10.3969/j.issn.1006-0111.2015.02.001
Citation: LIANG Hai, XIANG Zhuo, ZHANG Xuehui, WU Jiuhong. Reviews on flavanone compounds synthesis research[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 97-101,130. doi: 10.3969/j.issn.1006-0111.2015.02.001
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