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辐射致组织损伤凋亡机制的研究概况

杨宏 倪敏 赵心彬 陶霞

杨宏, 倪敏, 赵心彬, 陶霞. 辐射致组织损伤凋亡机制的研究概况[J]. 药学实践与服务, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
引用本文: 杨宏, 倪敏, 赵心彬, 陶霞. 辐射致组织损伤凋亡机制的研究概况[J]. 药学实践与服务, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
YANG Hong, NI Min, ZHAO Xinbin, TAO Xia. Role of apoptosis in radiation-induced tissue damage[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
Citation: YANG Hong, NI Min, ZHAO Xinbin, TAO Xia. Role of apoptosis in radiation-induced tissue damage[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005

辐射致组织损伤凋亡机制的研究概况

doi: 10.3969/j.issn.1006-0111.2014.02.005

Role of apoptosis in radiation-induced tissue damage

  • 摘要: 辐射能够导致组织损伤,其机制通常与细胞凋亡、坏死、炎症等相关。其中细胞凋亡是辐射损伤的主要特征之一,但是凋亡发生的具体机制仍不清楚。研究表明,有多条通路涉及其中,代表性的通路有:聚ADP核糖聚合酶(PARP)、p53、自由基、神经酰胺、p38通路等。本文围绕上述蛋白质分子,综述了凋亡途径在辐射致组织损伤的作用。
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  • 收稿日期:  2013-03-11
  • 修回日期:  2013-06-14

辐射致组织损伤凋亡机制的研究概况

doi: 10.3969/j.issn.1006-0111.2014.02.005

摘要: 辐射能够导致组织损伤,其机制通常与细胞凋亡、坏死、炎症等相关。其中细胞凋亡是辐射损伤的主要特征之一,但是凋亡发生的具体机制仍不清楚。研究表明,有多条通路涉及其中,代表性的通路有:聚ADP核糖聚合酶(PARP)、p53、自由基、神经酰胺、p38通路等。本文围绕上述蛋白质分子,综述了凋亡途径在辐射致组织损伤的作用。

English Abstract

杨宏, 倪敏, 赵心彬, 陶霞. 辐射致组织损伤凋亡机制的研究概况[J]. 药学实践与服务, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
引用本文: 杨宏, 倪敏, 赵心彬, 陶霞. 辐射致组织损伤凋亡机制的研究概况[J]. 药学实践与服务, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
YANG Hong, NI Min, ZHAO Xinbin, TAO Xia. Role of apoptosis in radiation-induced tissue damage[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
Citation: YANG Hong, NI Min, ZHAO Xinbin, TAO Xia. Role of apoptosis in radiation-induced tissue damage[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
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