纳米结构脂质载体用于难溶性药物口服传递的研究进展
Progress on nanostructured lipid carriers as oral poorly soluble drugs delivery systems
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摘要: 纳米结构脂质载体可以提高难溶性药物的口服生物利用度,是一种具有前景的难溶性药物口服传递系统.通过查阅文献,对纳米结构脂质载体常见的制备材料、方法,体外表征和释药,及提高难溶性药物口服生物利用度的机制进行综述.Abstract: Nanostructured lipid carrier,which could enhance the bioavailability of poorly soluble drugs,was a kind of promisingoral delivery systems for insoluble drugs.The preparation,characterization, drug release in vitro and the mechanism of NLC for enhancing the bioavailability of poorly soluble were reviewed in this paper.
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