323例药物不良反应报告分析
Analysis of 323 cases of adverse drug reactions reports
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摘要: 目的: 通过对我院2005年323例药物不良反应(ADR)报表进行统计分析,研究ADR的发生率与患者年龄及用药情况的关系。 方法: 采用描述性研究方法对ADR报表进行分类。 结果: 涉及ADR的药物共有194个品种,其中抗感染类药物引起的ADR发生率最高,抗肿瘤药次之。而ADR引发的组织器官损伤最常见于皮肤过敏反应及消化系统症状。 结论: 应重视安全合理用药,最大限度地减少ADR的重复发生。Abstract: Objective: To investigate 323 reports of adverse drug reactions(ADRs)in our hospital in 2005,and to analyze the re- lationship between ADRs and age,the used drugs. Methods: The cases of ADR were analyzed by descriptive study. Results: 194 kinds of drugs were involved in.Among them,49(25.30%)kinds were antibiotis in the first rank,40(20.60%)kinds were antineo- plastic agents in second rank.ADR showed the lesion of skin and digestive system mostly. Conclusion: Great attention should be paid to the development of ADR so as to reduce the incidence of ADR.
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Key words:
- adverse drug reactions(ADRs) /
- ADR monitoring /
- statistical analysis
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