细辛伍用维拉帕米对小鼠的镇痛作用
Analgesic action of composition of Asarum and verapamil in mice
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摘要: 目的 观察细辛水煎剂伍用维拉帕米配制成复方细辛水煎剂的镇痛作用,为其临床应用提供理论依据。方法 采用扭体法,热板法测定细辛、维拉帕米及复方细辛对小鼠的镇痛作用。结果 复方细辛全身给药有显著镇痛作用,且比其配方组分(细辛和维拉帕米)的单方制剂作用强,有一定协同效应。结论 维拉帕米可增强细辛水煎剂的镇痛作用。二者合用不失为一种有效中西药结合组方的镇痛药。Abstract: OBJECTIVE To observe analgesic action of composition Asarum decoction made up of Asarum water decoction and verapamil by the experiment in mice. METHODS:The method of turning round the body and hot plate were used in mice. RESULTS Composite Asarum has significant analgesic action by general application and its action is more powerful than that of the sole Asarum or the sole verapamil. CONCLUSION Verapamil can enhance the analgesic action of Asarum water decoction. Composition Asarum and verapamil can be applied as an effident analgesic drug.
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Key words:
- composition Asarum decoction /
- Asarum /
- verapamil /
- analgesic action
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