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2024 Vol. 42, No. 12

Cover Catalogue
Original articles
Screening and anti-colorectal activity of small molecule inhibitors of Fusobacterium nucleatum
BAI Xuexin, CHEN Yuping, SHENG Chunquan, WU Shanchao
2024, 42(12): 503-507. doi: 10.12206/j.issn.2097-2024.202405009
Abstract(4626) HTML (1636) PDF (1629KB)(29)
Abstract:
Objective  To screen small molecule inhibitors of Fusobacterium nucleatum (Fn) based on commercially available compound libraries, and investigate their anti-colorectal cancer activities under Fn intervention in order to obtain novel anti-colorectal...
The protective effect of a traditional chinese medicine composition on ANIT induced liver injury in mice with cholestasis
YANG Nian, ZHANG Bole, ZHANG Junxia, ZHANG Zhenqiang
2024, 42(12): 508-511, 519. doi: 10.12206/j.issn.2097-2024.202305008
Abstract(5913) HTML (2366) PDF (2046KB)(45)
Abstract:
Objective  To explore the protective effect of a traditional chinese medicine composition on ANIT induced cholestasis liver injury in mice.   Methods  8-week old SPF Kunming mice were randomly divided into 6 groups, 10 mice in each group which wer...
Cost-effectiveness analysis of posaconazole versus voriconazole in the empiric or diagnostic-driven treatment of invasive mould diseases in immunocompromised patients
SHI Xiaoping, LYU Qianzhou, LI Xiaoyu, XU Qing
2024, 42(12): 512-519. doi: 10.12206/j.issn.2097-2024.202401050
Abstract(1571) HTML (1124) PDF (1455KB)(16)
Abstract:
Objective  To evaluate the cost-effectiveness of posaconazole compared with voriconazole in the empiric or diagnostic-driven treatment of invasive mould diseases (IMD) in immunocompromised patients from the perspective of Chinese health system.   M...
Medicine & Clinical
Application of eliminating flatulence and laxative cream in advanced hepatocellular carcinoma patients with opioid-associated constipation
HE Yalun, QI Zhi, CHANG Jie
2024, 42(12): 520-523. doi: 10.12206/j.issn.2097-2024.202309009
Abstract(5580) HTML (1573) PDF (883KB)(14)
Abstract:
Objective  To evaluate the curative effect ofeliminating flatulence and laxative cream on patients with advanced hepatocellular carcinoma and opioid-associated constipation(OIC).   Methods  120 patients with advanced liver cancer complicated with ...
Clinical curative effect of Pingchuan prescription combined with montelukast sodium on patients with bronchial asthma
CHEN Chunjuan, ZHENG Zhixin, LI Li
2024, 42(12): 524-527, 532. doi: 10.12206/j.issn.2097-2024.202405035
Abstract(2675) HTML (973) PDF (1226KB)(13)
Abstract:
Objective  To explore the clinical curative effect of Pingchuan prescription combined with montelukast sodium on patients with bronchial asthma.   Methods  A total of 102 patients with bronchial asthma admitted to the hospital were enrolled betwee...
Retrospective analysis of the epidemic characteristics of Gram-negative bacteria in a second-class hospital in Shanghai
DAI Feifei, FU Xiang, CHEN Qiongnian, YU Suchun
2024, 42(12): 528-532. doi: 10.12206/j.issn.2097-2024.202305005
Abstract(1753) HTML (1219) PDF (1003KB)(9)
Abstract:
Objective  To retrospectively analyze the distribution and drug resistant characteristics of isolated pathogens (especially Gram-negative bacteria) in hospital and promote the rational use of antibacterial drugs.   Methods  The pathogens and drug ...
Pharmacy Administration
The approaches and implications of emergency drug authorization by the U.S. FDA
HAN Dan, GAO Wen, WANG Lunuan, SUN Rui, GUO Mingming, SHU Lixin
2024, 42(12): 533-536. doi: 10.12206/j.issn.2097-2024.202309044
Abstract(1492) HTML (631) PDF (869KB)(7)
Abstract:
Objective  To provide valuable insights for improving China’s special drug approval system by conducting an in-depth analysis of the practices of the U.S. Food and Drug Administration (FDA) in granting Emergency Use Authorizations (EUAs) for drugs. ...
A brief discussion on the development and challenges of smoking cessation services led by pharmacist abroad
WEN Ruirui, XU Long, ZHU Wenjing, YANG Jianwei
2024, 42(12): 537-541, 548. doi: 10.12206/j.issn.2097-2024.202408054
Abstract(1521) HTML (500) PDF (1290KB)(3)
Abstract:
Objective  To investigate the role of pharmacists in smoking cessation abroad and foster the dissemination and initiation of smoking cessation services led by pharmacist.   Methods  A search and compiles information on the value of pharmacists in ...
Quantitative evaluation on internal control of drug management in a tertiary public hospital in Shanghai
XU Fei, LIU Ying, YIN Jia, ZHU Guoliang, LIAN Luying
2024, 42(12): 542-548. doi: 10.12206/j.issn.2097-2024.202402003
Abstract(2389) HTML (2493) PDF (1084KB)(17)
Abstract:
Objective  To establish the quantitative evaluation system on the internal control of drug management, which could reflect the improvement and optimization of the internal control of drug management and be reference for the drug management in the ho...