2020 Vol. 38, No. 3
Display Method:
2020, 38(3): 193-201.
doi: 10.12206/j.issn.1006-0111.202003163
Abstract:
Objective To explore the molecular targets and related potential pathways of Jinzhen oral liquid in the treatment of coronavirus disease 2019 (COVID-19). Methods The potential blood-entry active ingredients and targets of Jinzhen oral liquid we...
2020, 38(3): 202-206, 210.
doi: 10.12206/j.issn.1006-0111.202003098
Abstract:
The novel coronavirus pneumonia is an acute respiratory infectious disease mainly manifested by fever, fatigue and dry cough, caused by new coronavirus 2019-nCoV infection（COVID-19）. Traditional Chinese Medicine played an important role in the preven...
The novel coronavirus pneumonia is an acute respiratory infectious disease mainly manifested by fever, fatigue and dry cough, caused by new coronavirus 2019-nCoV infection（COVID-19）. Traditional Chinese Medicine played an important role in the preven...
Clinical medication response under new major infectious disease: off-label use and compassionate use
2020, 38(3): 207-210.
doi: 10.12206/j.issn.1006-0111.202003035
Abstract:
At present, there are no specific targeted drugs for the treatment of pneumonia (COVID-19) caused by the novel coronavirus (SARS-CoV-2). Interferon, lopinavir/ritonavir, ribavirin, chloroquine phosphate were chosen as off-label use, and remdesivir wa...
At present, there are no specific targeted drugs for the treatment of pneumonia (COVID-19) caused by the novel coronavirus (SARS-CoV-2). Interferon, lopinavir/ritonavir, ribavirin, chloroquine phosphate were chosen as off-label use, and remdesivir wa...
2020, 38(3): 211-215, 226.
doi: 10.12206/j.issn.1006-0111.201910034
Abstract:
Indanomycins are a class of secondary metabolites of microorganisms with a trans-tetrahydroindan (indane) ring. These compounds generally have good antibacterial, insecticidal and antitumor biological activities, which have caused wide interest for m...
Indanomycins are a class of secondary metabolites of microorganisms with a trans-tetrahydroindan (indane) ring. These compounds generally have good antibacterial, insecticidal and antitumor biological activities, which have caused wide interest for m...
2020, 38(3): 216-220.
doi: 10.12206/j.issn.1006-0111.201912159
Abstract:
Objective To evaluate the anti-inflammatory effects of LCA, which is the active component from Litsea cubeba (Lour.) Pers. Methods Pharmacodynamic evaluations of ear swelling and cotton ball granuloma models were used in animal experiments. In ...
2020, 38(3): 221-226.
doi: 10.12206/j.issn.1006-0111.201912074
Abstract:
Objective To investigate the effect of tetrahydrobiopterin (BH4), superoxide dismutase-polyethylene glycol (PEG-SOD) and N(G)-nitro-L-arginine (L-NNA) on impaired endothelial progenitor cell (EPC) functions in DOCA-salt hypertensive mice. Methods...
2020, 38(3): 227-231, 258.
doi: 10.12206/j.issn.1006-0111.202001005
Abstract:
Objective To distinguish the structural analogues xanthine, theophylline and theobromine by surface-enhanced Raman spectroscopy. Methods Concentrated silver colloid enhancement reagent was prepared as the Raman substrate to increase the number ...
2020, 38(3): 232-236.
doi: 10.12206/j.issn.1006-0111.202001045
Abstract:
Objective To investigate the effects of calycosin, formononetin, calycosin-7-glucoside and ononin on PC 12 cells differentiation. Methods PC 12 cells were cultured and treated with different concentrations of nerve growth factor (NGF), calycosi...
2020, 38(3): 237-240, 249.
doi: 10.12206/j.issn.1006-0111.201907036
Abstract:
Objective To study the pharmacokinetics of HMS-01 in rats and provide support for subsequent study. Methods A sensitive and specific method for the determination of HMS-01 in plasma and other biological samples was established by LC-MS/MS. The ...
2020, 38(3): 241-244, 276.
doi: 10.12206/j.issn.1006-0111.201912008
Abstract:
Objective Breast cancer is one of the deadliest malignancies in the world. ebracteolatain A (EA) is a kind of acetylphloroglucinol extracted from ebracteolatain. To explore the specific mechanism of EA inhibiting the proliferation of breast cancer ...
2020, 38(3): 245-249.
doi: 10.12206/j.issn.1006-0111.202001049
Abstract:
Obejctive To determine and compare britanin content in dried aerial parts and capitulum of Inula linariifolia Turcz from 7 different origins by HPLC. Methods Analysis was performed on Agilent Zorbax SB C18 (250 mm×4.6 mm, 5 μm). Acetonitrile an...
2020, 38(3): 250-254, 267.
doi: 10.12206/j.issn.1006-0111.201906027
Abstract:
Objective To identify the blood components of Fuzheng Huayu capsule by ultra performance liquid chromatography-high resolution time-of-flight mass spectrometry (UHPLC-Q-TOF/MS). Methods ACQUITY UPLCHSS T3 (2.1 mm × 100 mm, 1.8 μm) was used to c...
2020, 38(3): 255-258.
doi: 10.12206/j.issn.1006-0111.202002002
Abstract:
Objective To develop a high-performance liquid chromatography-diode array detector (HPLC-DAD) method for determination of cinnamic acid in the decoction of cinnamon, and investigate the effect of different storage temperature and time for the stabi...
2020, 38(3): 259-263.
doi: 10.12206/j.issn.1006-0111.201911005
Abstract:
Objective To establish the fingerprint spectrum and assay three active components (hesperidin, salvianolic acid B and chrysophanol) in Shenshuaining granule by HPLC method. Methods The chromatographic separation was achieved on SunFireTM C18 co...
2020, 38(3): 264-267.
doi: 10.12206/j.issn.1006-0111.201911114
Abstract:
Objective To establish a method for Emodin assay in Ampelopsis radix, and to improve the quality control of Ampelopsis radix. Methods Reversed phase high performance liquid chromatography was used. The column: Apollo-C18 (4.6 mm×250 mm, 5 μm); ...
2020, 38(3): 268-272.
doi: 10.12206/j.issn.1006-0111.201912165
Abstract:
Objective To compare the perioperative application of sufentanil and oxycodone in patients undergoing laparoscopic surgery for gastric or colorectal cancer. Methods 59 patients were selected and randomly divided into group O and group S. Anesth...
2020, 38(3): 273-276.
doi: 10.12206/j.issn.1006-0111.201910080
Abstract:
Objective To analyze the correlation of valproic acid and its metabolites (2-propyl-4-pentenoic acid, 3-hydroxy valproic acid,5-hydroxy valproic acid) with liver injury reference index. Methods 328 plasma samples from epilepsy patients were col...
2020, 38(3): 277-281.
doi: 10.12206/j.issn.1006-0111.202002057
Abstract:
Objective To investigate the current situation and existing problems of community chronic disease management in China and provide a theoretical basis for community chronic disease management to reduce the mortality and economic burden. Methods ...
2020, 38(3): 282-285, 288.
doi: 10.12206/j.issn.1006-0111.201912088
Abstract:
To ensure the safety and efficacy of the military thermo-sensitive drugs, it is necessary to monitor the temperature changes through the whole process of production, transportation, storage, distribution and application. The characteristics of variou...
To ensure the safety and efficacy of the military thermo-sensitive drugs, it is necessary to monitor the temperature changes through the whole process of production, transportation, storage, distribution and application. The characteristics of variou...
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