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2010 Vol. 28, No. 3

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2010, 28(3): 161-163,188.
Abstract(2498) PDF (709KB)(2066)
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2010, 28(3): 164-166,180.
Abstract(2238) PDF (210KB)(1321)
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2010, 28(3): 167-169,195.
Abstract(2506) PDF (214KB)(1289)
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Optimization study on preparation technology of falcate crazyweed herb cream
CHEN Jian-da, HONG Jia-ni, DU Qing-yun
2010, 28(3): 170-172.
Abstract(2661) PDF (191KB)(690)
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Objective To optimize the formulation and preparation process of falcate crazyweed herb cream of O/W type. Methods The orthogonal experimental design is applied.By investigating the emulsification conditions impacting the quality and stability of t...
Influence of danshensu on hemodynamics of anesthetic dog
CHEN Wei-zhong, CHEN Da-gui, JIAO Yong, ZHANG Chuan
2010, 28(3): 173-176.
Abstract(2367) PDF (276KB)(370)
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Objective To observe the influence of danshensu-sodium injection on the hemodynamics of anesthetic dog including heart rate,blood pressure,cardiac systolic/diastolic function. Methods The hemodynamics of dog after injected danshensu-sodium injectio...
Pharmacokinetics of levofloxacin in beagle dogs with open abdominal wound by different seawater immersion process
WANG Qianga, ZHANG Yia, SHANG Li-qun, YU Ji-yaoc, YU Cun-linga, WANG Da-pengb
2010, 28(3): 177-180.
Abstract(2488) PDF (270KB)(456)
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Objective To compare the pharmacokinetics of levofloxacin(LVFX) between beagle dogs with open abdominal wound by seawater immersion for different time and normal dogs. Methods Twelve healthy beagle dogs were randomly divided into control group(A gr...
Study on the protection mechanism of UTP against cerebral ischemia reperfusion injury in rats
TIAN Mou-lia, LI Tie-junb, LIU Hua, ZOU Zuia, SHI Xue-yina
2010, 28(3): 181-183,234.
Abstract(2114) PDF (272KB)(463)
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Objective To observe the protective effect of uridine 5'-triphosphate(UTP) on cerebral ischemia reperfusion(IR) injury in rats. Methods The injury model of middle cerebral artery occlusion(MCAO) was established by suture method.UTP were delivered t...
Study on preparation and dissolution of andrographolide self-emulsifying drug delivery soft capsules
MENG Hui, XU Yong
2010, 28(3): 184-185,208.
Abstract(2618) PDF (189KB)(1021)
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Objective To prepare the andrographolide self-emulsifying drug delivery soft capsules(ASESC) and evaluate its quality. Methods The andrographolide self-emulsifying soft capsules were prepared.To screen the dissolution of andrographolide,the dissolu...
Determination of trehalose in Candida albicans by HPLC-MS
DONG Ling-ling, CAO Ying-ying, CHAI Yi-feng
2010, 28(3): 186-188.
Abstract(2452) PDF (215KB)(585)
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Objective To establish a high performance liquid chromatography-mass spectrum(HPLC-MS) method to determine trehalose in the biofilm of Candida albicans. Methods Shisheido CAPCELL NH2(150 mm×4.6 mm,5 μm) was used in this method and the mobile phase ...
The protective effect of wikstromol on cultured cortical neurons induced by H2O2 and excitatory neurotransmitter
YE Li, ZHU De-qiu, YE Xian-cheng
2010, 28(3): 189-192.
Abstract(2712) PDF (283KB)(472)
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Objective To identify the material basis of the novel neuroprotective compounds from traditional chinese medicine Daphne giraldii in the treatment of neurodegenerative disorders.

Methonds Activity-guided fractionation of several chromatographic tec...
Experimental studies on anti-inflammatory and analgesic action of the Tongmaiyushang capsule
WU Xue-bin, YU Hui-hua, Tang Liang, YOU Ben-ming
2010, 28(3): 193-195.
Abstract(2629) PDF (264KB)(369)
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Objective To study the anti-inflammatory and analgesic effects of Tongmaiyushang capsule. Methods Tumidness of small rat ears was induced by dimethylbenzene.Acute and chronic inflammation of rats were induced by carrageenin and tampon embedding res...
Simultanous determination of curculigoside and curculigoside B in the rhizome of Curculigo orchioides from different regions by HPLC-DAD
Zeng Qian, Ji Hui
2010, 28(3): 196-198.
Abstract(2719) PDF (211KB)(324)
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Objective To determine the content of curculigoside and curculigoside B in the rhizome of Curculigo orchioides from different regions,and provide scientific basis for production and clinical application of these medicinal materials. Methods Accordi...
Determination of ephedrine and pseudoephedrine in Xuanfei Qingre mixture by HPLC
LIU Hui-jun, CHEN Rui, WANG Juan
2010, 28(3): 199-200,205.
Abstract(3126) PDF (213KB)(811)
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Objective To set up a method of simultaneously determining the contents of ephedrine and pseudoephedrine in Xuanfei Qingre mixture(Herba Ephedrae,Semen Armeniacae amarum,Bulbus Fritillaria thunbergii,Radix scutellaria,etc). Methods The HPLC-quantit...
Determination of residual organic solvents in orlistat by headspace gas chromatography
WEN Yan, WEN Jun, TAO Xia
2010, 28(3): 201-202.
Abstract(2372) PDF (147KB)(539)
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Objective To establish a method for determination of four residual organic solvents in orlistat. Methods The residual organic solvents in orlistat are hexane、heptane、methanol and acetonitril.They were quantitatively determined by headspace gas chro...
Orthogonal design of formula optimization for Huanggui enema
DENG Li-qin, ZHANG Yan
2010, 28(3): 203-205.
Abstract(2444) PDF (166KB)(492)
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Objective To choose the best formula for Huanggui enema. Methods The orthogonal test was used to optimize formula,and the clearance index in mice and antibacterial action in vitro were observation index.The best formula was designed according to th...
Effect on gel microcolumn assay of ceftazidime IgM and IgG in human serum with red cells packed by drug under different pH
LIN Guan-yang, GUO Hong, YU Lei
2010, 28(3): 206-208.
Abstract(2337) PDF (223KB)(834)
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Objective To observe the effect on gel microcolumn assay of ceftazidime IgM and/or IgG in human serum with red cells packed by drug under different pH. Methods Drug-coated red blood cells were prepared by incubating 10 volumes of ceftazidime in the...
Optimization of extraction process of compound Shuiniujiao granule by orthogonal test
CAO Wen, XU Dao-long, LI Tie-jun
2010, 28(3): 209-210,222.
Abstract(2140) PDF (164KB)(495)
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Objective To select the best extraction process in preparation of compound Shuiniujiao granule. Methods The extraction solvent,add water,extraction times and extraction time as the study factors,each factor orthogonal design method developed three ...
2010, 28(3): 211-212,214.
Abstract(1890) PDF (172KB)(1364)
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Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection
WEI Jing-hai
2010, 28(3): 213-214.
Abstract(2638) PDF (390KB)(551)
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Objective To study the stability of glucose and sodium potassium chloride injection(GNK) mixing with cefepime hydrochloride in room temperature. Methods RP-HPLC was applied to determine the content change of cefepime hydrochloride in different time...
The complex forming ability of medium substituted degree hydroxypropyl-β-cyclodextrins on dexamethasone
ZHANG Yue
2010, 28(3): 215-216,240.
Abstract(2803) PDF (295KB)(831)
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Objective To investigate synthesis of medium substituted degree hydroxypropyl-β-cyclodextrins and the complex forming capability of dexamethasone. Methods Medium substituted degree hydroxypropyl-β-cyclodextrins were prepared and tested by pharmacop...
Synthesis of hairpin-polyamides containing β-alanine
LI Peng
2010, 28(3): 217-219,231.
Abstract(3006) PDF (363KB)(390)
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Objective To develop a new method and strategy for the synthesis of hairpin-polyamides containingβ-alanine. Methods The hairpin-polyamides were synthesized by the HOBT/DCC coupling reaction in good yields through the optimization of hydrogenation o...
Synthesis and anoxia endurance activity of thiadiazole derivatives
ZHU Zhan-zhou
2010, 28(3): 220-222.
Abstract(2872) PDF (519KB)(280)
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Objective To design and synthesize novel thiadiazole derivatives and evaluate their anoxia endurance activity. Methods Beginning with thiosemicarbazide,title compounds were synthesized in three steps,then the anoxia endurance activity was evaluated...
Comparison of total alkaloids content of Fructus Broussonetia from different habitats
PANG Su-qiu
2010, 28(3): 223-224.
Abstract(2500) PDF (130KB)(238)
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Objective To compare the total alkaloids content of Fructus Broussonetiae from different habitats. Methods Total alkaloids were isolated by acid-ethanol and determined by acid dye colorimetry method under 410nm. Results The calibration cure of alk...
Study on the chemical constituents of Crinum latifalium
WEN Qian
2010, 28(3): 225-227.
Abstract(2225) PDF (172KB)(351)
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Objective To investigate the chemical constituents of Crinum latifalium. Methods The chemical constituents of methanol extract of C.latifalium were seperated by various chromatography Methods.The structures of these chemical constituents were ident...
2010, 28(3): 228-231.
Abstract(1904) PDF (194KB)(321)
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2010, 28(3): 232-234.
Abstract(2007) PDF (177KB)(255)
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2010, 28(3): 235-240.
Abstract(1987) PDF (419KB)(1293)
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