2006 Vol. 24, No. 4
Display Method:
2006, (4): 203-205.
Abstract:
Objective: To observe the antinoeiceptive effect of total Ervatamia yunnansis alkaloid(TEYA) in mice. Methods: The mice hot-plate antinociceptve test was used to study the analgesic effects of TEYA and the effect on morphine in mice. Results: The three groups with different dosage of TEYA could significantly increase the pain threshold in mice and the effects increased in a dose-related manner. TEYA(10、20 mg/kg) combined with morphine 4 mg/kg had a synergic analgesic effect. The analgesic effect of TEYA could he partly blocked by naloxone 4 mg/kg. There were significantly differences between administration group and control group in the hot-plate test. Conclusion: TEYA has significant antinoeiceptive activity in hot-plate lest in mice which may be mediated by way of opioid receptors.
Objective: To observe the antinoeiceptive effect of total Ervatamia yunnansis alkaloid(TEYA) in mice. Methods: The mice hot-plate antinociceptve test was used to study the analgesic effects of TEYA and the effect on morphine in mice. Results: The three groups with different dosage of TEYA could significantly increase the pain threshold in mice and the effects increased in a dose-related manner. TEYA(10、20 mg/kg) combined with morphine 4 mg/kg had a synergic analgesic effect. The analgesic effect of TEYA could he partly blocked by naloxone 4 mg/kg. There were significantly differences between administration group and control group in the hot-plate test. Conclusion: TEYA has significant antinoeiceptive activity in hot-plate lest in mice which may be mediated by way of opioid receptors.
2006, (4): 205-206.
Abstract:
Objective: To establish a method for the determination of the contents of sulfate groups in polysulfated heparin sodium. Methods: The contents of sulfate groups were determined by converting the Na+ of polysulfated heparin sodium into H+ with cation exchange resin and titrating with sodium hydroxide. The titration end-point was ascertained by variance of conductivity and the results were rectified by cetylpyridinium chloride. Results: The average recovery was 100. 18% ,RSD = 3. 67% . Conclusion: This mthod was simple,reproducible and accurate.
Objective: To establish a method for the determination of the contents of sulfate groups in polysulfated heparin sodium. Methods: The contents of sulfate groups were determined by converting the Na+ of polysulfated heparin sodium into H+ with cation exchange resin and titrating with sodium hydroxide. The titration end-point was ascertained by variance of conductivity and the results were rectified by cetylpyridinium chloride. Results: The average recovery was 100. 18% ,RSD = 3. 67% . Conclusion: This mthod was simple,reproducible and accurate.
2006, (4): 207-208,251.
Abstract:
Objective: To observe the hemolysis, stimulation and hypersensitivity of ganciclovir glucose injection. Methods: The stimulation reaction on blood vessel of rabbit,the hemolysis and agglomeration reaction on vitro-body red cell of rabbit and the hypersensitivity reaction on guine-pig of ganciclovir glucose injection were studied. Results: The results showed no stimulation on blood vessel of rabbits, no hemolysis and agglomeration on vitro-body red cells of rabbit and no hypersensitive action on guinea-pig. Conclusion: Ganciclovir glucose injection has no hemolysis,hypersensitive and stimulative reaction.
Objective: To observe the hemolysis, stimulation and hypersensitivity of ganciclovir glucose injection. Methods: The stimulation reaction on blood vessel of rabbit,the hemolysis and agglomeration reaction on vitro-body red cell of rabbit and the hypersensitivity reaction on guine-pig of ganciclovir glucose injection were studied. Results: The results showed no stimulation on blood vessel of rabbits, no hemolysis and agglomeration on vitro-body red cells of rabbit and no hypersensitive action on guinea-pig. Conclusion: Ganciclovir glucose injection has no hemolysis,hypersensitive and stimulative reaction.
2006, (4): 216-218.
Abstract:
Objective: To explore a bacterial endotoxin test for Houttuynia cordata injection. Methods: The bacterial endoloxin test was experimented according to the requirement of the second volum of China Pharmacopoeia,2000 edition. Results: The interference factors could be excluded in the Houttuynia cordata diluted to 4 times, the bacterial endotoxin could be determined effectively by 0. 25 EU/mL of TAL. Conclusion: The pyrogen notoxin in Houttuynia cordata injection can be determined by LLA.
Objective: To explore a bacterial endotoxin test for Houttuynia cordata injection. Methods: The bacterial endoloxin test was experimented according to the requirement of the second volum of China Pharmacopoeia,2000 edition. Results: The interference factors could be excluded in the Houttuynia cordata diluted to 4 times, the bacterial endotoxin could be determined effectively by 0. 25 EU/mL of TAL. Conclusion: The pyrogen notoxin in Houttuynia cordata injection can be determined by LLA.
2006, (4): 222-225.
Abstract:
Objective: To find the effective method to identify Bupleurum chinense and B. scorzoneraefolium with B. smithii wolff var. parvifolium Shan et Y. Li. and B.bicaule Helm. Methods: All the varieties including the confusion vartieties were identified by observing the shape and characters, comparing the transverse section microstructure of radix.TCL also was used to classify the varieties. Results: It is clearly that Bupleurum chinense DC. and B. scorzoneraefolium Willd. are different from B. smithii wolff var. parvifolium Shan et Y. Li. and B.bicaule Helm. Conclusion: Bupleurum chinense DC. and B. scorzoneraefolium Willd. can be effectively identified by experience identification,microscope and TCL.
Objective: To find the effective method to identify Bupleurum chinense and B. scorzoneraefolium with B. smithii wolff var. parvifolium Shan et Y. Li. and B.bicaule Helm. Methods: All the varieties including the confusion vartieties were identified by observing the shape and characters, comparing the transverse section microstructure of radix.TCL also was used to classify the varieties. Results: It is clearly that Bupleurum chinense DC. and B. scorzoneraefolium Willd. are different from B. smithii wolff var. parvifolium Shan et Y. Li. and B.bicaule Helm. Conclusion: Bupleurum chinense DC. and B. scorzoneraefolium Willd. can be effectively identified by experience identification,microscope and TCL.
2006, (4): 226-228.
Abstract:
Objective: To discuss the ways and methods of pharmaceutical care in retail pharmacy. Methods: Information, based on pharmaceutical care consultation records and drug history database from 2003/7 to 2006/3 in GPP drug-store of Shanghai No. 1 Pharmacy CO. ,LTD. , was analyzed statistically. Results: There are 72 records concerning medicine consultation monthly, 90% of the consultants being middle and old aged people and including the problems of diseases, medicine selection, usage, side effect and drug price. Conclusion: Consumers strongly need retail pharmacy to provide pharmaceutical care and retail drug-store should actively practice "Guideline of Good Pharmacy Practice". Pharmacist in retail drug-store should play their key role in pharmaceutical care to meet the growing need of society in health.
Objective: To discuss the ways and methods of pharmaceutical care in retail pharmacy. Methods: Information, based on pharmaceutical care consultation records and drug history database from 2003/7 to 2006/3 in GPP drug-store of Shanghai No. 1 Pharmacy CO. ,LTD. , was analyzed statistically. Results: There are 72 records concerning medicine consultation monthly, 90% of the consultants being middle and old aged people and including the problems of diseases, medicine selection, usage, side effect and drug price. Conclusion: Consumers strongly need retail pharmacy to provide pharmaceutical care and retail drug-store should actively practice "Guideline of Good Pharmacy Practice". Pharmacist in retail drug-store should play their key role in pharmaceutical care to meet the growing need of society in health.
2006, (4): 238-241,243.
Abstract:
Objective: To investigate the utility of antibiotics in respiratory department in our hospital during 2002-2004. Methods: 200 cases were collected randomly from inpatients' case, the utility of antibiotics were analyzed and DUI was taken as the analytical judgment index. Results: The antibiotic whose DUI≤1 accounted for about 60% of all cases. The average utility of antibiotics was 19. 14% in sun of drugs used in respiratory department from 2002 to 2004. This percentage was lower than percentage of average level in the whole country, which was 27.97 % . Conclusion: The utility of antibiotics were basically rational in respiratory department of our hospital;However, there are still some improper united uses of antibiotics. The rational utility of antibiotics must be strengthened.
Objective: To investigate the utility of antibiotics in respiratory department in our hospital during 2002-2004. Methods: 200 cases were collected randomly from inpatients' case, the utility of antibiotics were analyzed and DUI was taken as the analytical judgment index. Results: The antibiotic whose DUI≤1 accounted for about 60% of all cases. The average utility of antibiotics was 19. 14% in sun of drugs used in respiratory department from 2002 to 2004. This percentage was lower than percentage of average level in the whole country, which was 27.97 % . Conclusion: The utility of antibiotics were basically rational in respiratory department of our hospital;However, there are still some improper united uses of antibiotics. The rational utility of antibiotics must be strengthened.
Contribution System
Author Login
Review Login
Editor Login
Reader Login
News