1998 Vol. 16, No. 4
Display Method:
1998, (4): 193-195.
Abstract:
The pharmacokineties of vitamine E microcapsules were studied. Concentration of plasma was determined by UV after ig 100mg/kg Vitamin E of vitamin E microcapsules being given rabbits.The pharmacokineties of vitamin E fitted to a two-compartment medal with lag time using PKBP-N1 program. The results of vitamin E microcapsules is: t1/2Ka=3. 246±1.667h, t1/2α=7.150±1.899, t1/2β=38.305±13.34h, Cmax=8.625±2.404mg/L;Tmax=12. 10±3.807;AUC0～∞=298.36±80.20h·mg/L.
The pharmacokineties of vitamine E microcapsules were studied. Concentration of plasma was determined by UV after ig 100mg/kg Vitamin E of vitamin E microcapsules being given rabbits.The pharmacokineties of vitamin E fitted to a two-compartment medal with lag time using PKBP-N1 program. The results of vitamin E microcapsules is: t1/2Ka=3. 246±1.667h, t1/2α=7.150±1.899, t1/2β=38.305±13.34h, Cmax=8.625±2.404mg/L;Tmax=12. 10±3.807;AUC0～∞=298.36±80.20h·mg/L.
1998, (4): 218-220.
Abstract:
We studied the method of preparation and qulality control of compound ofloxacin ear drop.The determination of ofloxacin was established by ultroaviolet spectrophotometry at the wavelength 293nm. The stability of compound ofloxacin ear drops were tested. Therapeutic results showed the reliable curative effect, safety and practical.
We studied the method of preparation and qulality control of compound ofloxacin ear drop.The determination of ofloxacin was established by ultroaviolet spectrophotometry at the wavelength 293nm. The stability of compound ofloxacin ear drops were tested. Therapeutic results showed the reliable curative effect, safety and practical.
1998, (4): 222-224.
Abstract:
The stability of aminophylline in four transfusion solutions were studied. The result showed that aminophylline was stable when combined with 0.9% sodium chloride injection under 25℃ and 37℃, their appearances, pH, ultraviolet spectrum and content had almost no change within 24 hours: when combined with glucose and sodium chloride injection,5% glucose injection, 10% glucose injection under 25℃ and 37℃, their pH was declined slightly, appearances color was deepens after 12 hours, but their ultraviolet spectrum and content had no change within 24 hours. The result can be used for reference in clinical practice.
The stability of aminophylline in four transfusion solutions were studied. The result showed that aminophylline was stable when combined with 0.9% sodium chloride injection under 25℃ and 37℃, their appearances, pH, ultraviolet spectrum and content had almost no change within 24 hours: when combined with glucose and sodium chloride injection,5% glucose injection, 10% glucose injection under 25℃ and 37℃, their pH was declined slightly, appearances color was deepens after 12 hours, but their ultraviolet spectrum and content had no change within 24 hours. The result can be used for reference in clinical practice.
1998, (4): 230-232.
Abstract:
A method of determination by UV spectrophotometry and identification by thin-layer chromatography of tetracaine hydrochloride eye drop was established. The maximum absorbance wavel ength at 310±1nm was selected for determination wavelength, ethyl hydroxybenzoate has no interferrence. The result showed that the absorbance coeffecient (E1cm1%) of tetracaine hydrochloride at 310±1nm was 760,RSD=0.5% (n=20), the mean recovery for sample was 99.5%, RSD=0.5% (n=7). This method is simple, rapid, accurate and reproducible.
A method of determination by UV spectrophotometry and identification by thin-layer chromatography of tetracaine hydrochloride eye drop was established. The maximum absorbance wavel ength at 310±1nm was selected for determination wavelength, ethyl hydroxybenzoate has no interferrence. The result showed that the absorbance coeffecient (E1cm1%) of tetracaine hydrochloride at 310±1nm was 760,RSD=0.5% (n=20), the mean recovery for sample was 99.5%, RSD=0.5% (n=7). This method is simple, rapid, accurate and reproducible.
1998, (4): 232-233.
Abstract:
The contente of sodium chloride injection was determinated by conductance. The recovery is 99.97%, RSD=0.32%. This method is simple, rapid and accurate.
The contente of sodium chloride injection was determinated by conductance. The recovery is 99.97%, RSD=0.32%. This method is simple, rapid and accurate.
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