1997 Vol. 15, No. 3
Display Method:
1997, (3): 151-153.
Abstract:
It was reported that a juvenile renal transplant patients had a low cyclosporine whole blood concentration after normal administration.The pharmacokinetic parameters were: T1/2(Ke) = 3.15h, Tmax = 1.88h,Cmax=498.41ng·ml-1,AUC=3188.65(ng·ml-1)·h-1.Computer software was used to design the individual administration, that was 200mg, tid. Satisfactory effect was acquired.
It was reported that a juvenile renal transplant patients had a low cyclosporine whole blood concentration after normal administration.The pharmacokinetic parameters were: T1/2(Ke) = 3.15h, Tmax = 1.88h,Cmax=498.41ng·ml-1,AUC=3188.65(ng·ml-1)·h-1.Computer software was used to design the individual administration, that was 200mg, tid. Satisfactory effect was acquired.
1997, (3): 154-157.
Abstract:
By the circulating in small intestine of rats, the absorbing behavior was compared between garlic oil and its inclusion compound with concentration of garlic oil as a examining index. After garlic oil and inclusion compound were circulated for 2.5 hour in the intestine, their absorption speed constants(Ka) were 0.9665h-1 and 0.2568h-1,respectively. Absorption halflife (t1/2) were 43.13 minutes and 2.65 hours, respectively. Absorption rates were 94.87%and 51.05%,respectively circulating of the compound in the intestine for 6 hours, absorption rates were about 80%.From the absorption curves, we knew that the absorption of the compound was slower, smoother and more permanent than that of garlic oil. The pathologicol findings were that inclusion compound could lower the irritation and toxicity of garlic oil to the intestine.
By the circulating in small intestine of rats, the absorbing behavior was compared between garlic oil and its inclusion compound with concentration of garlic oil as a examining index. After garlic oil and inclusion compound were circulated for 2.5 hour in the intestine, their absorption speed constants(Ka) were 0.9665h-1 and 0.2568h-1,respectively. Absorption halflife (t1/2) were 43.13 minutes and 2.65 hours, respectively. Absorption rates were 94.87%and 51.05%,respectively circulating of the compound in the intestine for 6 hours, absorption rates were about 80%.From the absorption curves, we knew that the absorption of the compound was slower, smoother and more permanent than that of garlic oil. The pathologicol findings were that inclusion compound could lower the irritation and toxicity of garlic oil to the intestine.
1997, (3): 166-168.
Abstract:
A method which was hydrochloric acid instead of acetic acid was used for detecting NO2-/NO3- in distilled water.It avoids frequent false positive from acetic acid.
A method which was hydrochloric acid instead of acetic acid was used for detecting NO2-/NO3- in distilled water.It avoids frequent false positive from acetic acid.
1997, (3): 173-175.
Abstract:
The method for determination of amantadine hydrochloride syrup by acid dye colorimetry was reported.Colorimetry conditions were choiced in this paper.It was not interfered by excipient and it was simple. The average recovery was 100.3%.The cofficient of varivation was 0.30%.
The method for determination of amantadine hydrochloride syrup by acid dye colorimetry was reported.Colorimetry conditions were choiced in this paper.It was not interfered by excipient and it was simple. The average recovery was 100.3%.The cofficient of varivation was 0.30%.
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