1996 Vol. 14, No. 5
Display Method:
1996, (5): 259-262,277.
Abstract:
The paper briefly reviews the statutory definition of prescription drug (Rx) and non-prescription drug (OTC),the statute and regulations of Rx&OTC classification system,and the criteria employed in determining whether a drug is marketed by prescription or OTC in the other countries.We then outline the legal procedures of Rx to OTC switches in the United States.
The paper briefly reviews the statutory definition of prescription drug (Rx) and non-prescription drug (OTC),the statute and regulations of Rx&OTC classification system,and the criteria employed in determining whether a drug is marketed by prescription or OTC in the other countries.We then outline the legal procedures of Rx to OTC switches in the United States.
1996, (5): 273-274.
Abstract:
Azone is a high percutaneous penetration enhancer.It can promote most drugs percutaneous absorption.Our study shows that the 20μg/ml concertration of Azone can produce obviously bacteriostasis for the gram-positive bacterium and the spore.
Azone is a high percutaneous penetration enhancer.It can promote most drugs percutaneous absorption.Our study shows that the 20μg/ml concertration of Azone can produce obviously bacteriostasis for the gram-positive bacterium and the spore.
1996, (5): 279-282.
Abstract:
The gel of compound metronidazole is at ransparent hydrophilic gel of carbomer 940,which consist of metronidazole and dexamethasone sodium phosphate.It is used topically to treat aphthous ulcer and peridental inflammation.We reported the preformulation,method of preparation,quantitative determination and the standard for quality of the gel in this paper.The metronidazole and dexamethasone sodium phosphate in the gel were analysed by the computer-aided convolution cure method without prior separation.These methods are simple and rapid.
The gel of compound metronidazole is at ransparent hydrophilic gel of carbomer 940,which consist of metronidazole and dexamethasone sodium phosphate.It is used topically to treat aphthous ulcer and peridental inflammation.We reported the preformulation,method of preparation,quantitative determination and the standard for quality of the gel in this paper.The metronidazole and dexamethasone sodium phosphate in the gel were analysed by the computer-aided convolution cure method without prior separation.These methods are simple and rapid.
1996, (5): 282-285.
Abstract:
Smear method was used to prepare film of ofloxacin compound with PVA0486-CMCNa(2:1) as the material of drug film,PVA0486 as the coating material.UV-spectropho-tometory was used to determine the content of metronidazole.The average recovery was 97.47%,RSD=1.61%
Smear method was used to prepare film of ofloxacin compound with PVA0486-CMCNa(2:1) as the material of drug film,PVA0486 as the coating material.UV-spectropho-tometory was used to determine the content of metronidazole.The average recovery was 97.47%,RSD=1.61%
1996, (5): 292-294.
Abstract:
The first order derivative UV spectrophotometry was for determination of ephedrine hydrochloride in its nasal drops to eliminate interference of ethyl p-hydroxyhenzoate.A good linearity has shown in the concentration of 5～25μg/ml,r=0.9999(n=5).The average recovery was 99.83% and cv was 0.49%.The method is simple,rapid and accurate.
The first order derivative UV spectrophotometry was for determination of ephedrine hydrochloride in its nasal drops to eliminate interference of ethyl p-hydroxyhenzoate.A good linearity has shown in the concentration of 5～25μg/ml,r=0.9999(n=5).The average recovery was 99.83% and cv was 0.49%.The method is simple,rapid and accurate.
1996, (5): 295-297.
Abstract:
A quantitative method was developed for the determination of puerarin in Gegen Qing lian Pian by reversed phase HPLC.Chromatographic conditions included column ODS-C(10),column temperature,35℃;detector UV,250nm;mobile phase,methanol-water(23:77),flow rate 1 ml/min;injecting volume,10μl;external standad.the number of theoretical plates calculated by puerarin peak was no less than 2000.The standard curve was linear in the concentration range of 5μg/ml-80μg/ml,and correlation coefficient was 0.9999.The average rccovery and the relative standsrd deviation were 97.6% and 1.8%,respectively.
A quantitative method was developed for the determination of puerarin in Gegen Qing lian Pian by reversed phase HPLC.Chromatographic conditions included column ODS-C(10),column temperature,35℃;detector UV,250nm;mobile phase,methanol-water(23:77),flow rate 1 ml/min;injecting volume,10μl;external standad.the number of theoretical plates calculated by puerarin peak was no less than 2000.The standard curve was linear in the concentration range of 5μg/ml-80μg/ml,and correlation coefficient was 0.9999.The average rccovery and the relative standsrd deviation were 97.6% and 1.8%,respectively.
1996, (5): 297-299.
Abstract:
Salidvn tablets have been separated and determinaed by capillary Gas chromatography.Salidvn was separated on a SE-54 column(0.25 mmid×25m),using hydrogen flame ionzgation detector(FID).There was a good linearity ranging from 0.3 to 1.3mg of salidvn (caffeine:r=0.9994, Y=1.5584χ-0.0257;aminopyrine: r=0.9992, Y=1.1653χ-0.0893;Phenobarbital: r=0.9998, Y=2.535χ-0·1754;Phenacetin: r=0.9995, Y=2.9554χ-0.1281).The average recovery rate were 100.2%,99.8%,100.5%, 98.4% respectively.
Salidvn tablets have been separated and determinaed by capillary Gas chromatography.Salidvn was separated on a SE-54 column(0.25 mmid×25m),using hydrogen flame ionzgation detector(FID).There was a good linearity ranging from 0.3 to 1.3mg of salidvn (caffeine:r=0.9994, Y=1.5584χ-0.0257;aminopyrine: r=0.9992, Y=1.1653χ-0.0893;Phenobarbital: r=0.9998, Y=2.535χ-0·1754;Phenacetin: r=0.9995, Y=2.9554χ-0.1281).The average recovery rate were 100.2%,99.8%,100.5%, 98.4% respectively.
1996, (5): 300-301,299.
Abstract:
A RP-HPLC method for the determination of Puerarin in isoflowonesd from Radix Puerariae and its preparations and a C 18 column and a mobile phase of methanol-water (25:75) were employed.Puerarin was determined at 250nm.The recovery rate of the Puerarin was 100.9%.The rigression equation was X=466.83+8501.25C(r=0.9991),The method is simple,sensitive and accurate.
A RP-HPLC method for the determination of Puerarin in isoflowonesd from Radix Puerariae and its preparations and a C 18 column and a mobile phase of methanol-water (25:75) were employed.Puerarin was determined at 250nm.The recovery rate of the Puerarin was 100.9%.The rigression equation was X=466.83+8501.25C(r=0.9991),The method is simple,sensitive and accurate.
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