1996 Vol. 14, No. 1
Display Method:
1996, (1): 9-11.
Abstract:
Effects of Chinese Stellera(Stellera chamaejsme L. ScL)on the growth of mouse tumor S180 in vivo and in vitro were studied. It wsa found that ScL inhibited the growth of transplanted mouse tumor S180,5-20g/kg(equivalent crude drug)ip for 10d, the inhibition rates of it against S180 were 16.2-47.8%. ScL inhibited the proliferation,MTT formazan formation and clonal formatrion of S-180 celles. The inhibition rate had a positive interrelationship with the concentration and exposure time. These results showed that ScL had an effective antitumor activity in vitro and in vivo.
Effects of Chinese Stellera(Stellera chamaejsme L. ScL)on the growth of mouse tumor S180 in vivo and in vitro were studied. It wsa found that ScL inhibited the growth of transplanted mouse tumor S180,5-20g/kg(equivalent crude drug)ip for 10d, the inhibition rates of it against S180 were 16.2-47.8%. ScL inhibited the proliferation,MTT formazan formation and clonal formatrion of S-180 celles. The inhibition rate had a positive interrelationship with the concentration and exposure time. These results showed that ScL had an effective antitumor activity in vitro and in vivo.
1996, (1): 12-14.
Abstract:
Twenty cases of protaglandin E1 suppository treatment against cor pulmonale complicated with respiratory failure and pulmonary hypertension were investigated. The reults show that TXB2 and PAmP were remarkably lower than those before the treatment(P<0.001), and 6-keto-PGF1a was significantly highter(P<0.001). Suggesting that prostaglandin E1 suppository is satisfactory during the treatment.
Twenty cases of protaglandin E1 suppository treatment against cor pulmonale complicated with respiratory failure and pulmonary hypertension were investigated. The reults show that TXB2 and PAmP were remarkably lower than those before the treatment(P<0.001), and 6-keto-PGF1a was significantly highter(P<0.001). Suggesting that prostaglandin E1 suppository is satisfactory during the treatment.
1996, (1): 23-26.
Abstract:
Lentinan is the dextran which is extracted from the seed of lentinus edodes(Berk)sing produced in Fujian province by DEAE cellulose chromatography and graded precipitation. Its molecular weight is 10-70×104 dalton. With methanol decomposition, periodic acid oxidation, Smithdegradation,methylation, gas chromatography and gaschromatography-mass spectrometer analysis, it was confirmed that the poly-branched structure is dextran with β(1→3)branched chain and β(1→3)main chain, Lentinan injection has been prepared. It has effect for the treatment of chronic virus hepatitis and tumor.
Lentinan is the dextran which is extracted from the seed of lentinus edodes(Berk)sing produced in Fujian province by DEAE cellulose chromatography and graded precipitation. Its molecular weight is 10-70×104 dalton. With methanol decomposition, periodic acid oxidation, Smithdegradation,methylation, gas chromatography and gaschromatography-mass spectrometer analysis, it was confirmed that the poly-branched structure is dextran with β(1→3)branched chain and β(1→3)main chain, Lentinan injection has been prepared. It has effect for the treatment of chronic virus hepatitis and tumor.
1996, (1): 31-32.
Abstract:
Concentration of alcohol, reflowing time and amont of alcohol was tested in cluster analysis for alcohol extracting procedure. Experimental results showed that reflowing time and concentration of alcohol were the significant facts to total anthraquinone content with P<0.01 and P<0.05 respectively. The best extracting procedure can be described as:the drug powder is reflowed 2 times, 1 hour each, percolated by 95% alcohol.
Concentration of alcohol, reflowing time and amont of alcohol was tested in cluster analysis for alcohol extracting procedure. Experimental results showed that reflowing time and concentration of alcohol were the significant facts to total anthraquinone content with P<0.01 and P<0.05 respectively. The best extracting procedure can be described as:the drug powder is reflowed 2 times, 1 hour each, percolated by 95% alcohol.
1996, (1): 32-34.
Abstract:
This paper reported the preparation of Lu-Mu-Er oral liquid and its quality control standard, clinical therapeutic results in 16 of patients with chronic bronchitis, based on the preliminary test of chemical constituents and antibechic,apophlegmatic, antisthmatic pharmacological test.
This paper reported the preparation of Lu-Mu-Er oral liquid and its quality control standard, clinical therapeutic results in 16 of patients with chronic bronchitis, based on the preliminary test of chemical constituents and antibechic,apophlegmatic, antisthmatic pharmacological test.
1996, (1): 37-40.
Abstract:
This article reviews the pharmacokinetic parameters and the progress on the determinating method of blood-drug concentration of common antineoplastics in nation.It offers the referencs for clinical rational use of drugs.
This article reviews the pharmacokinetic parameters and the progress on the determinating method of blood-drug concentration of common antineoplastics in nation.It offers the referencs for clinical rational use of drugs.
1996, (1): 46-47.
Abstract:
1996, (1): 47-48.
Abstract:
A sodium tetraphenylboron method has been studied to determine the contents of cimetidin tablets. The average recoveries was 99.88±0.42%. This method is smiple,rapid and accurate. The method provides consistent results comparable to those obtained from the assay defined in the CP(1990 edition)for four batches of tablets.
A sodium tetraphenylboron method has been studied to determine the contents of cimetidin tablets. The average recoveries was 99.88±0.42%. This method is smiple,rapid and accurate. The method provides consistent results comparable to those obtained from the assay defined in the CP(1990 edition)for four batches of tablets.
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