Study on quality standard of Xiangping chaqing paiqian granules
-
摘要: 目的 建立香平茶清排铅颗粒的质量标准。 方法 采用化学方法对香平茶清排铅颗粒中的维生素C进行鉴别;采用薄层色谱法(TLC)对该处方中的绿茶提取物、菊花提取物进行鉴别;采用高效液相色谱法(HPLC)测定处方中主要成分绿原酸和表儿茶素的含量。 结果 化学方法可鉴别维生素C;TLC法可鉴别出处方中绿茶提取物、菊花提取物;HPLC法测定绿原酸、表儿茶素的含量,线性良好,方法准确可靠,可以较好地控制该制剂的质量。 结论 所建立的方法准确可靠、灵敏度高、专属性强,可有效控制香平茶清排铅颗粒的质量。Abstract: Objective To establish a quality standard for Xiangping chaqing paiqian granules. Methods Chemical methods were used to identify vitamin C in the granules. TLC methods were used to identify green tea extracts and chrysanthemum extracts. Chlorogenic acid and catechin were assayed by HPLC. Results Vitamin C could be identified by chemical method, and green tea extracts and chrysanthemum extracts could be identified by TLC. The content of chlorogenic acid and catechin could be assayed by HPLC. Conclusion The methods were proved to be reliable, good sensitivity and high specificity, which could be used in quality control of Xiangping chaqing paiqian granules.
-
Key words:
- Xiangping chaqing paiqian granules /
- TLC /
- HPLC /
- quality standard
-
[1] 中国药典2010版.二部[S].2010:901. [2] 李 珏,贾 飞,吴永江.高效液相色谱法测定盐酸罗格列酮片的含量及有关物质[J].药学实践杂志,2012,30(1):49. [3] 张 蜀,邓 红,林华庆,等.青荔颗粒的制备及质量标准的初步研究[J].广东药学院报,2010,26(3):252.
计量
- 文章访问数: 2816
- HTML全文浏览量: 230
- PDF下载量: 263
- 被引次数: 0