[1] LOUVET A, MATHURIN P. Alcoholic liver disease: mechanisms of injury and targeted treatment[J]. Nat Rev Gastroenterol Hepatol, 2015, 12(4): 231-242. doi:  10.1038/nrgastro.2015.35
[2] STICKEL F, DATZ C, HAMPE J, et al. Pathophysiology and management of alcoholic liver disease: update 2016[J]. Gut Liver, 2017, 11(2): 173-188. doi:  10.5009/gnl16477
[3] GAO B, BATALLER R. Alcoholic liver disease: pathogenesis and new therapeutic targets[J]. Gastroenterology, 2011, 141(5): 1572-1585. doi:  10.1053/j.gastro.2011.09.002
[4] WANG H A, MEHAL W, NAGY L E, et al. Immunological mechanisms and therapeutic targets of fatty liver diseases[J]. Cell Mol Immunol, 2021, 18(1): 73-91. doi:  10.1038/s41423-020-00579-3
[5] LEUNG T M, LU Y K, YAN W, et al. Argininosuccinate synthase conditions the response to acute and chronic ethanol-induced liver injury in mice[J]. Hepatology, 2012, 55(5): 1596-1609. doi:  10.1002/hep.25543
[6] TSUKAMOTO H, LU S C. Current concepts in the pathogenesis of alcoholic liver injury[J]. FASEB J, 2001, 15(8): 1335-1349. doi:  10.1096/fj.00-0650rev
[7] SOZIO M, CRABB D W. Alcohol and lipid metabolism[J]. Am J Physiol Endocrinol Metab, 2008, 295(1): E10-E16. doi:  10.1152/ajpendo.00011.2008
[8] 朱雅丽, 季晨阳, 乐佳清, 等. 酒精与肝脏脂质代谢[J]. 生命科学, 2014, 26(8): 840-845.
[9] SHIMANO H, HORTON J D, HAMMER R E, et al. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a[J]. J Clin Invest, 1996, 98(7): 1575-1584. doi:  10.1172/JCI118951
[10] COSTET P, LEGENDRE C, MORÉ J, et al. Peroxisome proliferator-activated receptor α-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis[J]. J Biol Chem, 1998, 273(45): 29577-29585. doi:  10.1074/jbc.273.45.29577
[11] GAO L M, CHEN X Y, FU Z Y, et al. Kinsenoside alleviates alcoholic liver injury by reducing oxidative stress, inhibiting endoplasmic reticulum stress, and regulating AMPK-dependent autophagy[J]. Front Pharmacol, 2022, 12: 747325. doi:  10.3389/fphar.2021.747325
[12] CUI S C, YU J, ZHANG X H, et al. Antihyperglycemic and antioxidant activity of water extract from Anoectochilus roxburghii in experimental diabetes[J]. Exp Toxicol Pathol, 2013, 65(5): 485-488. doi:  10.1016/j.etp.2012.02.003
[13] DU X M, IRINO N, FURUSHO N, et al. Pharmacologically active compounds in the Anoectochilus and Goodyera species[J]. J Nat Med, 2008, 62(2): 132-148. doi:  10.1007/s11418-007-0169-0
[14] 何春年, 王春兰, 郭顺星, 等. 福建金线莲的化学成分研究[J]. 中国药学杂志, 2005, 40(8): 581-583. doi:  10.3321/j.issn:1001-2494.2005.08.007
[15] XIANG M, LIU T T, TIAN C, et al. Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway[J]. Pharmacol Res, 2022, 177: 106092. doi:  10.1016/j.phrs.2022.106092
[16] LU L, XIONG Y, LIN Z, et al. Advances in the therapeutic application and pharmacological properties of kinsenoside against inflammation and oxidative stress-induced disorders[J]. Front Pharmacol, 2022, 13: 1009550. doi:  10.3389/fphar.2022.1009550
[17] BERTOLA A, MATHEWS S, KI S H, et al. Mouse model of chronic and binge ethanol feeding(the NIAAA model)[J]. Nat Protoc, 2013, 8(3): 627-637. doi:  10.1038/nprot.2013.032
[18] ZENG X Z, LI X, XU C S, et al. Schisandra sphenanthera extract (Wuzhi Tablet) protects against chronic-binge and acute alcohol-induced liver injury by regulating the NRF2-ARE pathway in mice[J]. Acta Pharm Sin B, 2017, 7(5): 583-592. doi:  10.1016/j.apsb.2017.04.002
[19] 周梅月, 全卉, 陈贺宁, 等. Gao-Binge酒精性肝病模型小鼠的损伤特点[J]. 肝脏, 2021, 26(12): 1407-1410. doi:  10.3969/j.issn.1008-1704.2021.12.030
[20] 安彦峰, 张雅琼, 冯德强. 金线莲药理和临床研究进展[J]. 中国现代中药, 2014, 16(8): 685-687.
[21] GONÇALVES I O, PASSOS E, ROCHA-RODRIGUES S, et al. Physical exercise antagonizes clinical and anatomical features characterizing Lieber-DeCarli diet-induced obesity and related metabolic disorders[J]. Clin Nutr, 2015, 34(2): 241-247. doi:  10.1016/j.clnu.2014.03.010
[22] VALCIN J A, UDOH U S, SWAIN T M, et al. Alcohol and liver clock disruption increase small droplet macrosteatosis, alter lipid metabolism and clock gene mRNA rhythms, and remodel the triglyceride lipidome in mouse liver[J]. Front Physiol, 2020, 11: 1048. doi:  10.3389/fphys.2020.01048
[23] BIDAULT G, VIRTUE S, PETKEVICIUS K, et al. SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation[J]. Nat Metab, 2021, 3(9): 1150-1162. doi:  10.1038/s42255-021-00440-5
[24] FISCHER M, YOU M, MATSUMOTO M, et al. Peroxisome proliferator-activated receptor α(PPARα)agonist treatment reverses PPARα dysfunction and abnormalities in hepatic lipid metabolism in ethanol-fed mice[J]. J Biol Chem, 2003, 278(30): 27997-28004. doi:  10.1074/jbc.M302140200
[25] SETSHEDI M, WANDS J R, DE LA MONTE S M. Acetaldehyde adducts in alcoholic liver disease[J]. Oxidative Med Cell Longev, 2010, 3(3): 178-185. doi:  10.4161/oxim.3.3.12288
[26] YUE R C, CHEN G Y, XIE G X, et al. Activation of PPARα-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance[J]. Free Radic Biol Med, 2021, 174: 249-263. doi:  10.1016/j.freeradbiomed.2021.08.005