聚乙二醇400 介导的多西他赛脂肪乳剂与多西他赛注射液的稀释稳定性研究

张广军; 林玲; 陈丽娜; 高保安; 陈建明; 张广军; 林玲; 陈丽娜; 高保安; 陈建明

doi:10.3969/j.issn.1006-0111.2015.02.006

[1]

元英进,葛志强,冯霞.抗癌新药紫杉醇和多烯紫杉醇[M].北京:化学工业出版社,2002:5-10.

[2]

张先林.抗肿瘤药多西紫杉醇制剂的应用研究近况[J].药学进展,2006,30(11):516-517.

[3]

朱雷,沈琦.多西他赛注射液制备及质量控制[J].西北药学杂志,2010,25(2):121-123.

[4]

Baker SD, Zhao M, He P, et al. Simultaneous analysis of docetaxel and the formulation vehicle polysorbate 80 in human plasma by lipid chromatography/tandem mass spectrometry[J].Analyt Biochem,2004,324:276-284.

[5]

张晓庆,刘明忠,张利斌.注射用多西他赛与不同溶媒配伍稳定性的研究[J].药学服务与研究,2007,7(2):150-151.

[6]

Jing X, Deng L, Gao B,et al. A novel polyethylene glycol mediated lipid nanoemulsion as drug delivery carrier for paclitaxel[J/OL].Nanomedicine, (2013-08-20)[2013-11-26]. http://dx.doi.org/10.1016/j.nano.2013.07.018.

[7]

Han J,Davis SS,Papandreou C,et al.Design and evaluation of an emulsion vehicle for paclitaxel I physicochemical properties and plasma stability[J].Pharm Res,2004,21(9):1573-1580.