[1] THAKRAL S, YADAV A, SINGH V, et al. Alzheimer's disease: Molecular aspects and treatment opportunities using herbal drugs[J]. Ageing Research Reviews, 2023, 88: 101960.
[2] LIU N, HAZIYIHAN A, ZHAO W, et al. Trajectory of brain-derived amyloid beta in Alzheimer’s disease: where is it coming from and where is it going?[J]. Translational Neurodegeneration, 2024, 13(1): 42.
[3] ZHANG X, WANG J, ZHANG Z, et al. Tau in neurodegenerative diseases: molecular mechanisms, biomarkers, and therapeutic strategies[J]. Translational Neurodegeneration, 2024, 13(1): 40.
[4] 戴建英, 王辉, 刘敏, 等. 阿尔茨海默病的病理模型及代谢组学研究进展[J]. 药学服务与研究, 2021, 21(4): 241-247,320.
[5] SONI U, SINGH K, JAIN D, et al. Exploring Alzheimer's disease treatment: Established therapies and novel strategies for future care[J]. European Journal of Pharmacology, 2025, 998: 177520.
[6] LI S, YANG J. Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine[J]. RSC Medicinal Chemistry, 2024, 15(12): 3950-3969.
[7] DHILLON S. Aducanumab: First Approval[J]. Drugs, 2021, 81(12): 1437-1443.
[8] LARKIN H D. Lecanemab Gains FDA Approval for Early Alzheimer Disease[J]. JAMA, 2023, 329(5): 363-363.
[9] KLOSE J, GRIEHL C, ROßNER S, et al. Natural Products from Plants and Algae for Treatment of Alzheimer's Disease: A Review[J]. Biomolecules, 2022, 12(5): 694.
[10] NOGALES C, MAMDOUH Z M, LIST M, et al. Network pharmacology: curing causal mechanisms instead of treating symptoms[J]. Trends Pharmacol Sci, 2022, 43(2): 136-150.
[11] HOPKINS A L. Network pharmacology: The next paradigm in drug discovery[J], 2008, 4: 682-690.
[12] 李梢. 中医药计算系统生物学与寒热证候研究[J]. 世界科学技术-中医药现代化, 2007, 9(1): 105-111.
[13] 吴驰, 刘奇, 张兰, 等. "益智调神"针法治疗阿尔茨海默病的理论探析与临证发挥[J]. 中国医药导报, 2025, 22(19): 100-104,114.
[14] 曹珊, 陈智慧, 秦静琪, 等. 中药及其有效成分治疗阿尔茨海默病研究进展[J]. 中国实验方剂学杂志, 2024, 30(10): 258-268.
[15] 雷霞, 王加朋, 佟玉良, 等. 六味地黄丸对阿尔茨海默病秀丽隐杆线虫模型的神经保护作用[J]. 中成药, 2024, 46(2): 615-619.
[16] 任金凤, 刘晓语, 游录妍, 等. 地黄饮子防治阿尔茨海默症和帕金森病的研究进展[J]. 世界科学技术-中医药现代化, 2024, 26(8): 2069-2075.
[17] LUO L, PAN Y, CHEN F, et al. Exploring the potential mechanism of Polygonatum sibiricum for Alzheimer’s disease based on network pharmacology and molecular docking: An observational study[J]. Medicine, 2024, 103(52): e40726.
[18] 解静, 高杉, 李琳, 等. 网络药理学在中药领域中的研究进展与应用策略[J]. 中草药, 2019, 50(10): 2257-2265.
[19] LI S, ZHANG B. Traditional Chinese medicine network pharmacology: theory, methodology and application[J]. Chin J Nat Med, 2013, 11(2): 110-120.
[20] 李亚美. 基于多学科交叉的中药药效物质基础研究方法和思路概述[J]. 中国中药杂志, 2015, 40(9): 1644-1648.
[21] CHEN B W, LI W X, WANG G H, et al. A strategy to find novel candidate anti-Alzheimer's disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants[J]. PeerJ, 2018, 6: e4756.
[22] CHEN H Y, CHEN J Q, LI J Y, et al. Deep Learning and Random Forest Approach for Finding the Optimal Traditional Chinese Medicine Formula for Treatment of Alzheimer's Disease[J]. J Chem Inf Model, 2019, 59(4): 1605-1623.
[23] HE X, ZHAO L, ZHONG W, et al. Insight into potent leads for alzheimer's disease by using several artificial intelligence algorithms[J]. Biomed Pharmacother, 2020, 129: 110360.
[24] JARRELL J T, GAO L, COHEN D S, et al. Network Medicine for Alzheimer's Disease and Traditional Chinese Medicine[J]. Molecules, 2018, 23(5): 1143.
[25] 孟雪莲, 张靖. 探讨防己生物碱成分防治阿尔茨海默病的作用机制——基于网络药理学和分子对接[J]. 辽宁大学学报(自然科学版), 2024, 51(4): 315-326.
[26] LIU Y, LI H, WANG X, et al. Anti-Alzheimers molecular mechanism of icariin: insights from gut microbiota, metabolomics, and network pharmacology[J]. Journal of Translational Medicine, 2023, 21(1): 277.
[27] GU L, LU J, LI Q, et al. A network-based analysis of key pharmacological pathways of Andrographis paniculata acting on Alzheimer's disease and experimental validation[J]. J Ethnopharmacol, 2020, 251: 112488.
[28] JIANG Y, LI S, XIE X, et al. Exploring the Mechanism of Panax notoginseng Saponins against Alzheimer's Disease by Network Pharmacology and Experimental Validation[J]. Evid Based Complement Alternat Med, 2021, 2021: 5730812.
[29] ZHOU F, HE K, GUAN Y, et al. Network pharmacology-based strategy to investigate pharmacological mechanisms of Tinospora sinensis for treatment of Alzheimer's disease[J], 2020, 259: 112940.
[30] FANG Z, TANG Y, YING J, et al. Traditional Chinese medicine for anti-Alzheimer's disease: berberine and evodiamine from Evodia rutaecarpa[J]. Chin Med, 2020, 15: 82.
[31] YE S, ZHANG S, ZHANG L, et al. Screening and experimental validation of modified Gandou Decoction-targeted inhibitors for alleviating AD components via network pharmacology, machine learning, and molecular dynamics simulation[J]. Frontiers in Pharmacology, 2025, 16: 1685866.
[32] CHEUNG S, ZHONG Y, WU L, et al. Mechanism interpretation of Guhan Yangshengjing for protection against Alzheimer’s disease by network pharmacology and molecular docking[J]. Journal of Ethnopharmacology, 2024, 328: 117976.
[33] YANG X, GUAN Y, YAN B, et al. Evidence-based complementary and alternative medicine bioinformatics approach through network pharmacology and molecular docking to determine the molecular mechanisms of Erjing pill in Alzheimer's disease[J]. Exp Ther Med, 2021, 22(5): 1252.
[34] XU W, REN B, ZHANG Z, et al. Network pharmacology analysis reveals neuroprotective effects of the Qin-Zhi-Zhu-Dan Formula in Alzheimer's disease[J]. Front Neurosci, 2022, 16: 943400.
[35] SHEN Y, ZHANG B, PANG X, et al. Network Pharmacology-Based Analysis of Xiao-Xu-Ming Decoction on the Treatment of Alzheimer's Disease[J]. Front Pharmacol, 2020, 11: 595254.
[36] MA Y, HUANG S, JIANG H, et al. Mechanism of Zhinao Capsule in Treating Alzheimer's Disease Based on Network Pharmacology Analysis and Molecular Docking Validation[J]. J Healthc Eng, 2022, 2022: 5708769.
[37] ZHANG Y, GUO K, ZHANG P, et al. Exploring the mechanism of YangXue QingNao Wan based on network pharmacology in the treatment of Alzheimer's disease[J]. Front Genet, 2022, 13: 942203.
[38] LUO Y, LI D, LIAO Y, et al. Systems Pharmacology Approach to Investigate the Mechanism of Kai-Xin-San in Alzheimer's Disease[J]. Front Pharmacol, 2020, 11: 381.
[39] WANG Y Z, MENG L, ZHUANG Q S, et al. Screening Traditional Chinese Medicine Combination for Cotreatment of Alzheimer's Disease and Type 2 Diabetes Mellitus by Network Pharmacology[J]. J Alzheimers Dis, 2021, 80(2): 787-797.