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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2011  >  29(4): 285-286,317

YAN Ying, HUANG Chen. Study on the chemical constituents of Cortex Meliae[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 285-286,317.
Citation: YAN Ying, HUANG Chen. Study on the chemical constituents of Cortex Meliae[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 285-286,317.
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Study on the chemical constituents of Cortex Meliae

  • The Central Hospital of Hengyang,Hengyang 421001,China

  • Received Date: 2011-06-03
  • Rev Recd Date: 2011-06-28
  • Objective To study the chemical constituents of Cortex Meliae. Methods Chromatographic techniques were employed to isolate and purify the chemical constituents of Cortex Meliae. Structures of the chemical constituents were elucidated by methods of IR, MS and NMR. Results Five compounds were isolated and identified as kulolactone (1), methyl kulonate (2), salanin (3), 1-tigloyltrichilinin (4) and β-sitosterol (5), respectively. Conclusion Compound 4 was a new limonoid and named as 1-tigloyltrichilinin.
  • [1] 中国药典2010版.一部[S]. 2010:189.
    [2] 顾静文,刘立鼎.楝属植物研究与应用概况[J].江西科学,1994,12(2):123.
    [3] Nakatani M, Iwashita T, Mizukawa K, et al. Trichilinin, a new hexacyclic limonoid from Trichilia roka[J]. Heterocycles,1987,26(1):43.
    [4] Siddiqui S, Siddiqui BS, Ghiasuddin, et al. Tetracyclic triterpenoids of the fruit coats of Azadirachta indica[J]. Nat Prod,1991,54(2):408.
    [5] Chiang CK, Chang FC.Tetracyclic triterpenoids from Melia azedarach L.-III[J]. Tetrahedron,1973,29(14):1911.
    [6] Kraus W,Cramer R.Novel tetranortriterpenoids with insect antifeeding activity from neem oil[J]. Liebigs Ann Chem,1981,1981(1),181.
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Study on the chemical constituents of Cortex Meliae

  • The Central Hospital of Hengyang,Hengyang 421001,China
  • Received Date: 2011-06-03
  • Rev Recd Date: 2011-06-28

Abstract: Objective To study the chemical constituents of Cortex Meliae. Methods Chromatographic techniques were employed to isolate and purify the chemical constituents of Cortex Meliae. Structures of the chemical constituents were elucidated by methods of IR, MS and NMR. Results Five compounds were isolated and identified as kulolactone (1), methyl kulonate (2), salanin (3), 1-tigloyltrichilinin (4) and β-sitosterol (5), respectively. Conclusion Compound 4 was a new limonoid and named as 1-tigloyltrichilinin.

YAN Ying, HUANG Chen. Study on the chemical constituents of Cortex Meliae[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 285-286,317.
Citation: YAN Ying, HUANG Chen. Study on the chemical constituents of Cortex Meliae[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 285-286,317.
shu

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