The clinical observation of the analgesia effect and safety of Fentanyl Transdermal System for day surgery patients with anus surgeries

Key words: 
• anus /
• analgesia /
• Fentanyl Transdermal System /
• tramadol /

Abstract: Objective To observe the analgesia effect and safety of Fentanyl Transdermal System and tramadol for day surgery patients with anus surgeries. Methods 120 cases of anus surgeries undergo spinal anesthesia were randomly divided into three groups.Patients of group A had Fentanyl Transdermal System affixed on for analgesia.Patients of group B were received an oral dose of 100 mg tramadol in 3 h after operation.Patients of group C had no analgesia.The analgesia effects of three groups were estimated with VAS score after operation in different time points.The sedation effects of three groups were estimated with Ramsay score after operation in different time points,while observing the occurrence of adverse reactions. Results The analgesia effect of group A and group B were superior to group C at 4,24,48 h after operation.But the analgesia effect of group A was superior to group B and group C at 24,48 h after operation.The sedation effect of group A was superior to group B and group C at 24,48 h after operation.And the sedation effect of group B was superior to group C at 24 h after operation.Only dizziness and drowsiness was higher significantly between group A and group C in the the incidence of adverse reactions.Methods The Fentanyl Transdermal System was a safe,simple and better effect medicament for ease the pain undergo the anus surgeries of day-case.