Determination of seven baleful trace elements in nine Chinese patent medicine treating diabetes mellitus

Key words: 
• ICP-MS /
• baleful trace elements /
• diabetes mellitus /
• Chinese Patent Medicine

Abstract: Objective To determine Pb,Cd,Hg,As,U,Th,Tl in nine clinical commonly used Chinese traditional medicine treating diabetes mellitus,which provide reference data for modern medication.Methonds The samples were treated by microwave digestion,and determined by ICP-MS. Results The Results showed that the contents of seven elements Pb,Cd,Hg,As,U,Th,Tl in these samples were detected,in which Pb,Cd,Hg,As were all accord with the Import Standards Draft of Green Plants for medical use and Southeast Asia Import Standards for Chinese Patent Medicine,but still had gap with Recommending Standard Graft of Traditional Medicine Quality Standards and Import Chinese Traditional Medicine Standards of France.Compared three radioactive elements such as U,Th,Tl,which showed that Th had the largest scope of content,and mean comparative Results is Th>U>Tl. Conclusion Some problems still exist when making contrast between content of harmful elements with that in food and medical standards.The contents of U,Th,Tl in samples were low,and hadn't poison effect on human.Much importance should be attached on the quality control of baleful trace elements in the production of Chinese Patent Medicines.