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Volume 27 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2009  >  27(5): 349-352

DONG Xin, LIU Min, ZHAO Jing-xia, ZHANG Wei, LOU Zi-yang. Research on constituents of Radix Aconiti and its processing by electrospray ionization trap mass spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(5): 349-352.
Citation: DONG Xin, LIU Min, ZHAO Jing-xia, ZHANG Wei, LOU Zi-yang. Research on constituents of Radix Aconiti and its processing by electrospray ionization trap mass spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(5): 349-352.
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Research on constituents of Radix Aconiti and its processing by electrospray ionization trap mass spectrometry

  • 1.

    Pharmaceutical Analysis Center, School of Pharmacy, the Second Military Medical University, SHANGHAI 200433, China

  • 2.

    Institute for Drug and Instrument Control of Nanjing Command, Nanjing 210002, China

  • Received Date: 2009-07-07
  • Objective : To reveal the processing principleg of preparation of Radix Aconiti by electrospray ionization trap mass spectrometry. Methods : The three reference standars were made MSn analysis and elucidating the fragmentation pathways.The rapid analysis by HPLC-ESI-MS had been used for identification of contituents in Radix Aconiti. Results :The comparison of mass spectra and liquid chromatographic information revealed the differences of Radix Aconiti and its process product. Conclusion : It is necessary to make quality control of process product of traditional Chinese herbal medicines by HPLC-ESI-MS.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Research on constituents of Radix Aconiti and its processing by electrospray ionization trap mass spectrometry

  • 1. Pharmaceutical Analysis Center, School of Pharmacy, the Second Military Medical University, SHANGHAI 200433, China
  • 2. Institute for Drug and Instrument Control of Nanjing Command, Nanjing 210002, China
  • Received Date: 2009-07-07

Abstract: Objective : To reveal the processing principleg of preparation of Radix Aconiti by electrospray ionization trap mass spectrometry. Methods : The three reference standars were made MSn analysis and elucidating the fragmentation pathways.The rapid analysis by HPLC-ESI-MS had been used for identification of contituents in Radix Aconiti. Results :The comparison of mass spectra and liquid chromatographic information revealed the differences of Radix Aconiti and its process product. Conclusion : It is necessary to make quality control of process product of traditional Chinese herbal medicines by HPLC-ESI-MS.

DONG Xin, LIU Min, ZHAO Jing-xia, ZHANG Wei, LOU Zi-yang. Research on constituents of Radix Aconiti and its processing by electrospray ionization trap mass spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(5): 349-352.
Citation: DONG Xin, LIU Min, ZHAO Jing-xia, ZHANG Wei, LOU Zi-yang. Research on constituents of Radix Aconiti and its processing by electrospray ionization trap mass spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(5): 349-352.
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