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Volume 27 Issue 3
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2009  >  27(3): 186-188

FU Qiu-sheng, YI Shu-zhen. Preparation and physicochemical properties of kaempferol-3-O-rutinoside phospholipids complex[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(3): 186-188.
Citation: FU Qiu-sheng, YI Shu-zhen. Preparation and physicochemical properties of kaempferol-3-O-rutinoside phospholipids complex[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(3): 186-188.
shu

Preparation and physicochemical properties of kaempferol-3-O-rutinoside phospholipids complex

  • Department of Pharmacy, Naval General Hospital, Chinese PLA, Beijing 100037, China

  • Received Date: 2009-02-19
  • Objective :To prepare kaempferol-3-O-rutinoside phospholipid complex and study its physic chemical properties. Methods :Solubility and water oil distribution coefficient of the complex were studied,and compared with kaempferol-3-O-rutinoside. Results :There were a great improvements in the solubility of kaempferol-3-O-rutinoside phospholipid complex both in water and in n-octanol.Some differences of apparent oil/water distribution coefficients in the systems consisted of different pH water and n-octanol were found between the complex and kaempferol-3-O-rutinoside. Conclusion :The drug-phospholipid complexes may show some superior chemico-physical properties and enhance the absorption of the drugs.
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Preparation and physicochemical properties of kaempferol-3-O-rutinoside phospholipids complex

  • Department of Pharmacy, Naval General Hospital, Chinese PLA, Beijing 100037, China
  • Received Date: 2009-02-19

Abstract: Objective :To prepare kaempferol-3-O-rutinoside phospholipid complex and study its physic chemical properties. Methods :Solubility and water oil distribution coefficient of the complex were studied,and compared with kaempferol-3-O-rutinoside. Results :There were a great improvements in the solubility of kaempferol-3-O-rutinoside phospholipid complex both in water and in n-octanol.Some differences of apparent oil/water distribution coefficients in the systems consisted of different pH water and n-octanol were found between the complex and kaempferol-3-O-rutinoside. Conclusion :The drug-phospholipid complexes may show some superior chemico-physical properties and enhance the absorption of the drugs.

FU Qiu-sheng, YI Shu-zhen. Preparation and physicochemical properties of kaempferol-3-O-rutinoside phospholipids complex[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(3): 186-188.
Citation: FU Qiu-sheng, YI Shu-zhen. Preparation and physicochemical properties of kaempferol-3-O-rutinoside phospholipids complex[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(3): 186-188.
shu

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