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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2009  >  27(2): 111-114

FEI Yi-ming, GONG Chun-gui. Experimental study of anti-inflammatory and analgesic effects of extracts of Solanum lyratum thumb[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(2): 111-114.
Citation: FEI Yi-ming, GONG Chun-gui. Experimental study of anti-inflammatory and analgesic effects of extracts of Solanum lyratum thumb[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(2): 111-114.
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Experimental study of anti-inflammatory and analgesic effects of extracts of Solanum lyratum thumb

  • 1.

    Department of Pharmacy, Traditional Chinese Medicine Hospital of Wuxi City, Wuxi 214000, China

  • 2.

    Department of Pharmacy, Eastern Hepatobiliary Hospital, Second Military Medical University, Shanghai 200438, China

  • Received Date: 2009-01-15
  • Objective : To investigate the anti-inflammatory and analgesic effects of extracts of Solanum lyratum Thumb. Methods : The anti-inflammatory and analgesic effects of alcohol extract and water extract from Solanum lyratum Thumb were observed by means of acetic acid inducing mouse writhing model,hot plate method,dimethylbenzene inducing ear edema model and carrageenan inducing rat voix pedis swell model. Results :It was found that alcohol extract and water extract from Solanum lyratum Thumb significantly reducing the writhing frequency induced by acetic acid,markedly increasing the pain threshold in mice induced by hot plate,evidently suppressing the mouse's ear edema induced by dimethylbenzene and significantly mitigating the rat voix pedis swell inducing by carrageenan.The role of water extract was better than which of alcohol extract. Conclusions :The water extract from solanum lyratum thumb has notable effects on anti-inflammation and analgesia.
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Experimental study of anti-inflammatory and analgesic effects of extracts of Solanum lyratum thumb

  • 1. Department of Pharmacy, Traditional Chinese Medicine Hospital of Wuxi City, Wuxi 214000, China
  • 2. Department of Pharmacy, Eastern Hepatobiliary Hospital, Second Military Medical University, Shanghai 200438, China
  • Received Date: 2009-01-15

Abstract: Objective : To investigate the anti-inflammatory and analgesic effects of extracts of Solanum lyratum Thumb. Methods : The anti-inflammatory and analgesic effects of alcohol extract and water extract from Solanum lyratum Thumb were observed by means of acetic acid inducing mouse writhing model,hot plate method,dimethylbenzene inducing ear edema model and carrageenan inducing rat voix pedis swell model. Results :It was found that alcohol extract and water extract from Solanum lyratum Thumb significantly reducing the writhing frequency induced by acetic acid,markedly increasing the pain threshold in mice induced by hot plate,evidently suppressing the mouse's ear edema induced by dimethylbenzene and significantly mitigating the rat voix pedis swell inducing by carrageenan.The role of water extract was better than which of alcohol extract. Conclusions :The water extract from solanum lyratum thumb has notable effects on anti-inflammation and analgesia.

FEI Yi-ming, GONG Chun-gui. Experimental study of anti-inflammatory and analgesic effects of extracts of Solanum lyratum thumb[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(2): 111-114.
Citation: FEI Yi-ming, GONG Chun-gui. Experimental study of anti-inflammatory and analgesic effects of extracts of Solanum lyratum thumb[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(2): 111-114.
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