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Volume 26 Issue 6
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2008  >  (6): 432-434,456

WANG Bin, HUANG He-zhou, ZHU Zhen-yu, ZHANG Hai, JI Song-gang, CHAI Yi-feng. Blending of crude Epimedium Brevicornum according to their HPLC fingerprints[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 432-434,456.
Citation: WANG Bin, HUANG He-zhou, ZHU Zhen-yu, ZHANG Hai, JI Song-gang, CHAI Yi-feng. Blending of crude Epimedium Brevicornum according to their HPLC fingerprints[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 432-434,456.
shu

Blending of crude Epimedium Brevicornum according to their HPLC fingerprints

  • 1.

    Department of Pharmacy,Eastern Hepatobiliary Surgery Hospital,Second Military Medical University,Shanghai 200433,China

  • 2.

    School of Pharmacy,Second Military Medical University,Shanghai 200433,China

  • 3.

    Department of Pharmacy No.401 Hospital of PLA,Qingdao 266071,China

  • Received Date: 2008-05-04
  • Objective: To find a new way of improving the quality of TCM,blendings of crude Epimedium Brevicornum from various sources were studied according to their Fingerprints. Methods: Systematic optimization was adopted to determine the mixing ratio of different kinds of non-genuine crude drugs in order to maximize the similarity,which is based on the cosine value between the fingerprints of genuine and non-genuine crude drugs respectively.Fingerprints data were collected after the blending. Results: The similarity of drugs was improved evidently,and it was in accordance with the calculation result. Conclusion: Quality improvement of TCM can be made by blending.Optimized blending of crude drugs might be an efficient method in making full use of the relatively inadequate TCM resources.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Blending of crude Epimedium Brevicornum according to their HPLC fingerprints

  • 1. Department of Pharmacy,Eastern Hepatobiliary Surgery Hospital,Second Military Medical University,Shanghai 200433,China
  • 2. School of Pharmacy,Second Military Medical University,Shanghai 200433,China
  • 3. Department of Pharmacy No.401 Hospital of PLA,Qingdao 266071,China
  • Received Date: 2008-05-04

Abstract: Objective: To find a new way of improving the quality of TCM,blendings of crude Epimedium Brevicornum from various sources were studied according to their Fingerprints. Methods: Systematic optimization was adopted to determine the mixing ratio of different kinds of non-genuine crude drugs in order to maximize the similarity,which is based on the cosine value between the fingerprints of genuine and non-genuine crude drugs respectively.Fingerprints data were collected after the blending. Results: The similarity of drugs was improved evidently,and it was in accordance with the calculation result. Conclusion: Quality improvement of TCM can be made by blending.Optimized blending of crude drugs might be an efficient method in making full use of the relatively inadequate TCM resources.

WANG Bin, HUANG He-zhou, ZHU Zhen-yu, ZHANG Hai, JI Song-gang, CHAI Yi-feng. Blending of crude Epimedium Brevicornum according to their HPLC fingerprints[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 432-434,456.
Citation: WANG Bin, HUANG He-zhou, ZHU Zhen-yu, ZHANG Hai, JI Song-gang, CHAI Yi-feng. Blending of crude Epimedium Brevicornum according to their HPLC fingerprints[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 432-434,456.
shu

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