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Volume 24 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2006  >  (2): 86-89

ZHANG Li-bin, ZHANG Xiao-qing, LIU Ming-zhong. Study on compatible stability of ampicloxacillin sodium for injection in five infusions[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 86-89.
Citation: ZHANG Li-bin, ZHANG Xiao-qing, LIU Ming-zhong. Study on compatible stability of ampicloxacillin sodium for injection in five infusions[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 86-89.
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Study on compatible stability of ampicloxacillin sodium for injection in five infusions

  • Deparment of Pharmacy , Shanghai Pulmonary Hospital, Shanghai 200433, China

  • Received Date: 2005-06-10
  • Objective : To investigate the compatible stability of ampicoxacillin sodium for injection in five infusions in different time and different temperature conditions. Methods : Ampicloxacillin sodium was dissolved in five infusions.Ampicillin and cloxacillin in ampicloxacillin sodium for injection were determined by HPLC,and the color changes of all infusions were observed. Results : The ampicillin and eloxacillin contents in ampicloxacillin sodium for injection declined with time and temperature increased.The most distinct were 5% glucose injection. Concision : Ampicloxacillin sodium for injection wasn't stable in 5% glucose, gluscose and sodium chloride injection.
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Study on compatible stability of ampicloxacillin sodium for injection in five infusions

  • Deparment of Pharmacy , Shanghai Pulmonary Hospital, Shanghai 200433, China
  • Received Date: 2005-06-10

Abstract: Objective : To investigate the compatible stability of ampicoxacillin sodium for injection in five infusions in different time and different temperature conditions. Methods : Ampicloxacillin sodium was dissolved in five infusions.Ampicillin and cloxacillin in ampicloxacillin sodium for injection were determined by HPLC,and the color changes of all infusions were observed. Results : The ampicillin and eloxacillin contents in ampicloxacillin sodium for injection declined with time and temperature increased.The most distinct were 5% glucose injection. Concision : Ampicloxacillin sodium for injection wasn't stable in 5% glucose, gluscose and sodium chloride injection.

ZHANG Li-bin, ZHANG Xiao-qing, LIU Ming-zhong. Study on compatible stability of ampicloxacillin sodium for injection in five infusions[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 86-89.
Citation: ZHANG Li-bin, ZHANG Xiao-qing, LIU Ming-zhong. Study on compatible stability of ampicloxacillin sodium for injection in five infusions[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 86-89.
shu

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