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Volume 17 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 1999  >  (5): 279-281

Liang Jun, Tang Xiaofang, Wei Xiaolong. Effects of gypenosides on neoplasm growth and immunity function of Lewis lung neoplasm grafted mice[J]. Journal of Pharmaceutical Practice and Service, 1999, (5): 279-281.
Citation: Liang Jun, Tang Xiaofang, Wei Xiaolong. Effects of gypenosides on neoplasm growth and immunity function of Lewis lung neoplasm grafted mice[J]. Journal of Pharmaceutical Practice and Service, 1999, (5): 279-281.
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Effects of gypenosides on neoplasm growth and immunity function of Lewis lung neoplasm grafted mice

  • 1.

    The Outpatient Department, Material and Supplying Station of Beijing Military District, Beijing 100071

  • 2.

  • 3.

  • Received Date: 1999-05-04
  • OBJECTIVE To study the effects of Gypenosides (GPs) on neoplasm growth, total number of splenic cells and NK cell activity. METHODS Antitumor experiment in mice was made and the total number of splen cells and NK cell activity were determined. RESULTS GPs could significantly inhibit the growth of Lewis lung cancer in mice. The inhibiting rates of tumor were (30.7±1.2)%,(51.5±2.5)% and (50.3±1.5)% (P<0.01) after ip GPs 10,20 and 40mg/kg,respectively. The total number of splenic cells and the NK cell activity of both PBL and splenic cells were elevated. CONCLUSION The antitumor effect of GPs is related to the elevated immunological function of tumor grafted mice.
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通讯作者: 陈斌, bchen63@163.com
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Effects of gypenosides on neoplasm growth and immunity function of Lewis lung neoplasm grafted mice

  • 1. The Outpatient Department, Material and Supplying Station of Beijing Military District, Beijing 100071
  • 2. 
  • 3. 
  • Received Date: 1999-05-04

Abstract: OBJECTIVE To study the effects of Gypenosides (GPs) on neoplasm growth, total number of splenic cells and NK cell activity. METHODS Antitumor experiment in mice was made and the total number of splen cells and NK cell activity were determined. RESULTS GPs could significantly inhibit the growth of Lewis lung cancer in mice. The inhibiting rates of tumor were (30.7±1.2)%,(51.5±2.5)% and (50.3±1.5)% (P<0.01) after ip GPs 10,20 and 40mg/kg,respectively. The total number of splenic cells and the NK cell activity of both PBL and splenic cells were elevated. CONCLUSION The antitumor effect of GPs is related to the elevated immunological function of tumor grafted mice.

Liang Jun, Tang Xiaofang, Wei Xiaolong. Effects of gypenosides on neoplasm growth and immunity function of Lewis lung neoplasm grafted mice[J]. Journal of Pharmaceutical Practice and Service, 1999, (5): 279-281.
Citation: Liang Jun, Tang Xiaofang, Wei Xiaolong. Effects of gypenosides on neoplasm growth and immunity function of Lewis lung neoplasm grafted mice[J]. Journal of Pharmaceutical Practice and Service, 1999, (5): 279-281.
shu

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