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Wang Haifeng, Wang Ran, Tang Xiaodong. A HPLC method for simultaneous determination of procaine and lidocaine in mixture[J]. Journal of Pharmaceutical Practice and Service, 1998, (6): 355-357.
Citation: Wang Haifeng, Wang Ran, Tang Xiaodong. A HPLC method for simultaneous determination of procaine and lidocaine in mixture[J]. Journal of Pharmaceutical Practice and Service, 1998, (6): 355-357.

A HPLC method for simultaneous determination of procaine and lidocaine in mixture

  • Procaine and Lidocaine in mixture were separated and simulboeously assayed by Reverse - phase HPLC, using Nova - pack C18 colum, 3.9 × 150min, a mixture of methyl alcohol, water, butylamine, acetic acide(600:400: 1. 2: 1 v/v) as mobile phase, external standard and 238um detector. The average recovery of 99.76% (RSD = 0.530% ), n = 3 for Lidocaine, 99. 44% (RSD 0.502% ) for procaine. The method is simple, rapid and acurate. The components have good liner relation and respative.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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A HPLC method for simultaneous determination of procaine and lidocaine in mixture

Abstract: Procaine and Lidocaine in mixture were separated and simulboeously assayed by Reverse - phase HPLC, using Nova - pack C18 colum, 3.9 × 150min, a mixture of methyl alcohol, water, butylamine, acetic acide(600:400: 1. 2: 1 v/v) as mobile phase, external standard and 238um detector. The average recovery of 99.76% (RSD = 0.530% ), n = 3 for Lidocaine, 99. 44% (RSD 0.502% ) for procaine. The method is simple, rapid and acurate. The components have good liner relation and respative.

Wang Haifeng, Wang Ran, Tang Xiaodong. A HPLC method for simultaneous determination of procaine and lidocaine in mixture[J]. Journal of Pharmaceutical Practice and Service, 1998, (6): 355-357.
Citation: Wang Haifeng, Wang Ran, Tang Xiaodong. A HPLC method for simultaneous determination of procaine and lidocaine in mixture[J]. Journal of Pharmaceutical Practice and Service, 1998, (6): 355-357.

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