Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 37 Issue 2
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2019  >  37(2): 156-161,169

FAN Jiateng, LU Feng, XU Jiyang. Research on the inhibitory effect of amphotericin B against Candida albicans by D-SERS[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(2): 156-161,169. doi: 10.3969/j.issn.1006-0111.2019.02.011
Citation: FAN Jiateng, LU Feng, XU Jiyang. Research on the inhibitory effect of amphotericin B against Candida albicans by D-SERS[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(2): 156-161,169. doi: 10.3969/j.issn.1006-0111.2019.02.011
shu

Research on the inhibitory effect of amphotericin B against Candida albicans by D-SERS

doi: 10.3969/j.issn.1006-0111.2019.02.011

  • College of life science and technology, China Pharmaceutical University, Nanjing 210000, China

  • Received Date: 2018-05-05
  • Rev Recd Date: 2018-11-13
  • Objective To develop a rapid method to characterize the inhibitory effect of amphotericin B(AMB) against Candida albicans by dynamic surface enhanced Raman spectroscopy(D-SERS). Methods D-SERS were applied to analyze the effect of AMB on the Raman spectra of C.albicans by examining the relationship between the peak intensity ratio and the concentration of drug at Raman shift at 656 cm-1 and 729 cm-1 under different interaction time by a sensitive C.albicans and different AMB concentrations. Results The peak intensity ratio was negatively correlated with the concentration of AMB,which could be used to describe the inhibitory effect of AMB on C.albicans in a certain concentration and action time. Conclusion This method could characterize the inhibitory effect of AMB against C.albicans rapidly,which provided a simpler and faster detection method for characterizing more drug-pathogen interactions.
  • [1] 廖万清.深部真菌感染治疗进展[C].2003中国中西医结合皮肤性病学术会议论文汇编,2003,597-600.
    [2] PFALLER M A. Nosocomial candidiasis:emerging species,reservoirs,and modes of transmission[J]. Clinical Infectious Diseases,1996,22(2):S89-S94.
    [3] SZWEDA P,GUCWA K,ROMANOWSKA E,et al. Mechanisms of azole resistance among clinical isolates of Candida glabrata in Poland[J]. J Med Microbiol,2015,64(6):610-619.
    [4] WHITE T C,MARR K A,BOWDEN R A. Clinical,cellular,and molecular factors that contribute to antifungal drug resistance[J]. Clin Microbiol Rev,1998,11(2):382-402.
    [5] FEKETE-FORGÁCS K,GYÜRE L,LENKEY B. Changes of virulence factors accompanying the phenomenon of induced fluconazole resistance in Candida albicans[J]. Mycoses,2000,43(7-8):273-279.
    [6] SANGUINETTI M,POSTERARO P,POSTERARO B. Echinocandin antifungal drug resistance in Candida species:a cause for concern[J]. Curr Infect Dis Rep,2010,12(6):437-443.
    [7] KHAN A A,JABEEN M,ALANAZI A M,et al. Antifungal efficacy of amphotericin B encapsulated fibrin microsphere for treating Cryptococcus neoformans infection in Swiss albino mice[J]. Braz J Infect Dis,2016,20(4):342-348.
    [8] BREHM-STECHER B F,JOHNSON E A. Single-cell microbiology:tools,technologies,and applications[J]. Microbiol Mol Biol Rev,2004,68(3):538-559,table of contents.
    [9] JORGENSEN J,FERRARO M. Antimicrobial susceptibility testing:a review of general principles and contemporary practices[J]. Clin Infect Dis,2009,49(11):1749-1755.
    [10] LI P,LIU H,YANG L,et al. The time-resolved D-SERS vibrational spectra of pesticide thiram[J]. Talanta,2013,117(22):39-44.
    [11] HE W,ZHOU Y T,WAMER W G,et al. Mechanisms of the pH dependent generation of hydroxyl radicals and oxygen induced by Ag nanoparticles[J]. Biomaterials,2012,33(30):7547-7555.
    [12] LIU H,YANG Z,MENG L,et al. Three-dimensional and time-ordered surface-enhanced raman scattering hotspot matrix[J]. J Am Chem Soc,2014,136(14):5332-5341.
    [13] ZHU Y,LI M,YU D,et al. A novel paper rag as ‘D-SERS’ substrate for detection of pesticide residues at various peels[J]. Talanta,2014,128:117-124.
    [14] YANG L,LI P,LIU H,et al. A dynamic surface enhanced Raman spectroscopy method for ultra-sensitive detection:from the wet state to the dry state[J]. Chem Soc Rev,2015,44(10):2837-2848.
    [15] TANG X,CAI W,YANG L,et al. Monitoring plasmon-driven surface catalyzed reactions in situ using time-dependent surface-enhanced Raman spectroscopy on single particles of hierarchical peony-like silver microflowers[J]. Nanoscale,2014,6(15):8612-8616.
    [16] WU M,LI H,LV D,et al. Dynamic-SERS spectroscopy for the in situ discrimination of xanthine analogues in ternary mixture[J]. Anal Bioanal Chem,2017,409(23):5569-5579.
    [17] FANG F,QI Y,LU F,et al. Highly sensitive on-site detection of drugs adulterated in botanical dietary supplements using thin layer chromatography combined with dynamic surface enhanced Raman spectroscopy[J]. Talanta,2016,146:351-357.
    [18] LEE P C,MEISEL D. Adsorption and surface-enhanced Raman of dyes on silver and gold sols[J]. J Phys Chem,1982,86(17):3391-3395.
    [19] JANA N R,GEARHEART L,MURPHY C J. Seed-mediated growth approach for shape-controlled synthesis of spheroidal and rod-like gold nanoparticles using a surfactant template[J].Adv Mater,2001,13(18):1389-1393.
    [20] PREMASIRI W R,LEE J C,SAUER-BUDGE A,et al.The biochemical origins of the surface-enhanced Raman spectra of bacteria:a metabolomics profiling by SERS[J]. Anal Bioanal Chem,2016,408(17):4631-4647.
    [21] SAYIN I,KAHRAMAN M,SAHIN F,et al.Characterization of yeast species using surface-enhanced Raman scattering[J]. Appl Spectrosc,2009,63(11):1276-1282.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2824) PDF downloads(364) Cited by()

Related
Proportional views

Research on the inhibitory effect of amphotericin B against Candida albicans by D-SERS

doi: 10.3969/j.issn.1006-0111.2019.02.011
  • College of life science and technology, China Pharmaceutical University, Nanjing 210000, China
  • Received Date: 2018-05-05
  • Rev Recd Date: 2018-11-13

Abstract: Objective To develop a rapid method to characterize the inhibitory effect of amphotericin B(AMB) against Candida albicans by dynamic surface enhanced Raman spectroscopy(D-SERS). Methods D-SERS were applied to analyze the effect of AMB on the Raman spectra of C.albicans by examining the relationship between the peak intensity ratio and the concentration of drug at Raman shift at 656 cm-1 and 729 cm-1 under different interaction time by a sensitive C.albicans and different AMB concentrations. Results The peak intensity ratio was negatively correlated with the concentration of AMB,which could be used to describe the inhibitory effect of AMB on C.albicans in a certain concentration and action time. Conclusion This method could characterize the inhibitory effect of AMB against C.albicans rapidly,which provided a simpler and faster detection method for characterizing more drug-pathogen interactions.

FAN Jiateng, LU Feng, XU Jiyang. Research on the inhibitory effect of amphotericin B against Candida albicans by D-SERS[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(2): 156-161,169. doi: 10.3969/j.issn.1006-0111.2019.02.011
Citation: FAN Jiateng, LU Feng, XU Jiyang. Research on the inhibitory effect of amphotericin B against Candida albicans by D-SERS[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(2): 156-161,169. doi: 10.3969/j.issn.1006-0111.2019.02.011
shu

    HTML

Reference (21)

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return