Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 36 Issue 6
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2018  >  36(6): 481-483,492

WU Lan, CAI Tongkai, ZHANG Lichao, JIANG Yuanying, CAO Yongbing. Study on animal models and mechanisms of systemic lupus erythematosus[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 481-483,492. doi: 10.3969/j.issn.1006-0111.2018.06.001
Citation: WU Lan, CAI Tongkai, ZHANG Lichao, JIANG Yuanying, CAO Yongbing. Study on animal models and mechanisms of systemic lupus erythematosus[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 481-483,492. doi: 10.3969/j.issn.1006-0111.2018.06.001
shu

Study on animal models and mechanisms of systemic lupus erythematosus

doi: 10.3969/j.issn.1006-0111.2018.06.001
  • 1.

    Center for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • 2.

    Department of Pharmacy, Shanghai Traditional Chinese Medicine Hospital, Shanghai 200071, China

  • 3.

    Center for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Shanghai TCM-Integrated Hospital Shanghai TCM-Integrated Research Institute of pulse tube disease, Shanghai 200082, China

  • Received Date: 2018-03-19
  • Rev Recd Date: 2018-09-12
  • Objective Systemic lupus erythematosus (SLE) models were mainly divided into spontaneous and induced models. Through the literature,spontaneous and induced SLE models and their main characteristics were reviewed, which provided references for the researchers to choose appropriate models for studying specific pathogenic mechanism and diagnostic criteria, searching for targeted treatment interventions and developing potential therapeutic drugs.
  • [1] WANG Z, XIE JY, XU H, et al. Effect of Matteuccia struthiopteris polysaccharides on systemic lupus erythematosus-like syndrome induced by Campylobacter jejuni in BALB/c mice[J]. Acta pharmaceutica Sinica, 2010, 45(6):711-717.
    [2] MOK CC, LAU CS. Pathogenesis of systemic lupus erythematosus[J]. J Clin Pathol, 2003, 56(7):481-490.
    [3] FLIERMAN R, DAHA MR. Pathogenic role of anti-C1q autoantibodies in the development of lupus nephritis:a hypothesis[J]. Mol Immunol, 2007, 44(1-3):133-138.
    [4] LIM P L, ZOUALI M. Pathogenic autoantibodies:Emerging insights into tissue injury[J]. Immunology Letters, 2006, 103(1):17-26.
    [5] ZHANG M, CARROLL MC. Natural antibody mediated innate autoimmune response[J]. Mol Immunol, 2007, 44(1-3):103-110.
    [6] HELYER BJ, et al. Nature(London),1963,197(4863):197-199.
    [7] THEOFILOPOULOS AN, DIXON FJ. Murine models of systemic lupus erythematosus[J]. Adv Immunol, 1985, 37:269-390.
    [8] MURPHY ED, et al.Genetic control of autoimmune Disease,3Eds.NewYork:Elsevier NorthHolland,1978:207-220.
    [9] MCPHEE CG, BUBIER JA, SPROULE TJ, et al. IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB.Yaa mice[J]. J Immunol, 2013, 191(9):4581-4588.
    [10] MURPHY ED, ROTHS JB. AY chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation[J]. Arthritis & Rheumatism, 1979, 22(11):1188-1194.
    [11] MURPHY ED, ROTHS JB. A Single gene model for massive lymphoproliferation with imm-une complex disease in new mouse strain MRL[J]. Life Sci. 1976.
    [12] 阎雨,方莲花,杜冠华.系统性红斑狼疮动物模型研究进展[J].中国实验动物学报. 2015:428-433.
    [13] KREFT B, YOKOYAMA H, NAITO T, et al. Dysregulated transforming growth factor-beta in neonatal and adult autoimmune MRL-lpr mice[J]. J Autoimmun, 1996, 9(4):463-472.
    [14] 吴言为.青蒿素衍生物SM934对系统性红斑狼疮的疗效及作用机制研究[D].2016:11-12.
    [15] LI H, ZHANG YY, SUN YN, et al. Induction of systemic lupus erythematosus syndrome in BALB/c mice by immunization with active chromatin[J]. Acta Pharmacol Sin, 2004, 25(6):807-811.
    [16] 力弘,章蕴毅,黄曦益,等.小鼠系统性红斑狼疮样综合征的诱导及病变特征[J].中国新药与临床杂志,2004,23(8):480-484.
    [17] ZHONG SP,WEN BG,HE KL.Chemical and physical nature ofactiveehrematin in SRS-lymphomamouse lymphocyte[J].Chin J Pathophysiol,1994,10(4):378-382.
    [18] 张晓丹,严尚学,王晶晶,等.淋巴细胞活性染色质诱导系统性红斑狼疮样小鼠模型研究[J].中国药理学通报,2011,27(5):728-732.
    [19] 高建新,马宝骊,谢雅莉,张汉明.长期空肠弯曲菌感染诱导的小鼠自身免疫综合征.上海免疫学杂志,1993,13(4):193-196
    [20] 徐叔云,卞如镰,陈修. 药理实验方法学(第三版)[M].北京:人民卫生出版社,2002:1462
    [21] WANG Z, LI H, XU H,et al. Beneficial effect of Bupleurum polysaccharides on autoimmune disease induced by Campylobacter jejuni in BALB/c mice[J]. J Ethnopharmacol, 2009, 124(3):481-487.
    [22] 王铮,谢俊云,徐晗,等.贯众总多糖对空肠弯曲杆菌诱导的系统性红斑狼疮样综合征小鼠的作用[J].药学学报,2010,45(6):711-717.
    [23] AL-BANNA N, RAGHUPATHY R, ALBERT M J. Correlation of proinflammatory and anti-Inflammatory cytokine levels with histopathological changes in an adult mouse lung model of campylobacter jejuni infection[J]. Clin Vaccine Immunol, 2008, 15(12):1780-1787.
    [24] MAK A, TAY SH. Environmental factors, toxicants and systemic lupus erythematosus[J]. Int J Mol Sci, 2014, 15(9):16043-16056.
    [25] MINHAS U, DAS P, BHATNAGAR A. Role of reactive intermediates in the immunopathogenesis of the pristane-induced Balb/c model of lupus[J]. Lupus, 2011, 20(13):1421-1425.
    [26] 高增燕,孙杰,王艳茹,等.降植烷诱导C57BL/J6狼疮性肾病.鼠模型的建立和生物学鉴定[J].苏州大学学报(医学版),2010,30(3):498-501.
    [27] 周小刚.脂质体槲皮素对Pristane诱导系统性红斑狼疮样小鼠模型的效应[D]. 郑州大学,2016,7-9.
    [28] MIZUTANI, SHAHEEN VM, YOSHIDA H, et al. Pristane induced autoimmunity ingermfree mice[J].Clin Immunol,2005,114(2):110-118.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(3873) PDF downloads(610) Cited by()

Related
Proportional views

Study on animal models and mechanisms of systemic lupus erythematosus

doi: 10.3969/j.issn.1006-0111.2018.06.001
  • 1. Center for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • 2. Department of Pharmacy, Shanghai Traditional Chinese Medicine Hospital, Shanghai 200071, China
  • 3. Center for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Shanghai TCM-Integrated Hospital Shanghai TCM-Integrated Research Institute of pulse tube disease, Shanghai 200082, China
  • Received Date: 2018-03-19
  • Rev Recd Date: 2018-09-12

Abstract: Objective Systemic lupus erythematosus (SLE) models were mainly divided into spontaneous and induced models. Through the literature,spontaneous and induced SLE models and their main characteristics were reviewed, which provided references for the researchers to choose appropriate models for studying specific pathogenic mechanism and diagnostic criteria, searching for targeted treatment interventions and developing potential therapeutic drugs.

WU Lan, CAI Tongkai, ZHANG Lichao, JIANG Yuanying, CAO Yongbing. Study on animal models and mechanisms of systemic lupus erythematosus[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 481-483,492. doi: 10.3969/j.issn.1006-0111.2018.06.001
Citation: WU Lan, CAI Tongkai, ZHANG Lichao, JIANG Yuanying, CAO Yongbing. Study on animal models and mechanisms of systemic lupus erythematosus[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 481-483,492. doi: 10.3969/j.issn.1006-0111.2018.06.001
shu

    HTML

Reference (28)

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return