DONG Yan, LIANG Xin, LI Li, XU Tao, XU Feng, DONG Wei. Optimization of extraction process of quercetin from Semen Plantaginis by orthogonal test[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(4): 351-354. doi: 10.3969/j.issn.1006-0111.2018.04.014
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DONG Yan, LIANG Xin, LI Li, XU Tao, XU Feng, DONG Wei. Optimization of extraction process of quercetin from Semen Plantaginis by orthogonal test[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(4): 351-354. doi: 10.3969/j.issn.1006-0111.2018.04.014
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Optimization of extraction process of quercetin from Semen Plantaginis by orthogonal test
- Received Date: 2017-11-29
- Rev Recd Date:
2018-03-05
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Abstract
Objective To search for the most effective condition of extracting quercetin from Semen Plantaginis. Methods Single factor experiments of extracting quercetin from Litchi Semen Plantaginis were carried out by HPLC. Ultrasonic power,extracting time,methanol percentage and solid/liquid ratio were selected as critical factors. Orthogonal array design L9(34) was carried out to search for the most efficient condition to extract quercetin. Results The influential factors for quercetin extraction were as follows, solid/liquid ratio>ultrasonic power>methanol percentage>extracting time. The most optimal condition was to use 40% methanol to extract for 40 min with 200 W ultrasonic power and a solid/liquid ratio of 1:40 (g/ml). Conclusion Under this optimal condition, the extraction yield of quercetin reached 0.79%. This condition offered a simple, stable and effective process to extract Quercetin from Semen Plantaginis.
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