XUAN Weidong, FAN Zhengping, HU Shuigen, XU Dedong. Study on hydrophilic chemical constituents from Thesium Chinensis Turcz[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(3): 270-273. doi: 10.3969/j.issn.1006-0111.2018.03.017
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XUAN Weidong, FAN Zhengping, HU Shuigen, XU Dedong. Study on hydrophilic chemical constituents from Thesium Chinensis Turcz[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(3): 270-273. doi: 10.3969/j.issn.1006-0111.2018.03.017
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Study on hydrophilic chemical constituents from Thesium Chinensis Turcz
- Received Date: 2017-12-04
- Rev Recd Date:
2018-01-17
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Abstract
Objective To investigate the hydrophilic chemical constituents from Thesium Chinensis Turcz. Methods The water extract of Thesium Chinensis Turcz. was adsorbed onto AB-8 resin column and eluted with 50% ethanol to give the hydrophilic portion TT50. TT50 was further separated and purified by repeated column chromatography on silica gel,Sephadex LH-20. The structures of these purified compounds were identified by NMR spectral analysis and comparison with the reported data. Results Six compounds were isolated and identified as kaempferol ( 1 ),kaempferol-3-O-glucoside ( 2 ),kaepmferol-3,7-di-O-β-D-glucopyranoside ( 3 ),kaempferol-3-O-L-rhamnopyranosyl(1→2)-β-D-glucopyranoside ( 4 ),kaemperol-3-O-α-L-rhamnopyranosyl(1→2)-[6-O-acetyl]-β-D-glucopyranoside ( 5 ),rutinoside ( 6 ). Conclusion The main constituents of TT50 were kaempferol glycosides. Compounds 4 and 5 were isolated from this plant for the first time.
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