Optimization of extraction technology for Toufu irrigation by orthogonal test

PENG Yong; CHEN Rujing; LIU Duo; CHAI Weihan; ZHU Quangang

doi:10.3969/j.issn.1006-0111.2018.02.016

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Objective To optimize the extraction process and improve the quality of Toufu irrigation. Methods Matrine assay was selected to be the indicator for the extraction efficacy. Orthogonal test was used to determine the optimal water amount, extraction time and extraction frequency. Results The best extraction process was to extract 90 minutes twice with the water amount 8 times of the dry herbal material by weight. Conclusion This process is feasible and repeatable. It can be used for the quality control of the preparation.

Optimization of extraction technology for Toufu irrigation by orthogonal test

1. Shanghai Jiading Hospital of TCM, Shanghai 201899, China

2. Shanghai Dermatology Hospital, Shanghai 200443, China

Received Date: 2017-11-27

Rev Recd Date: 2017-12-04

Key words:

Abstract: Objective To optimize the extraction process and improve the quality of Toufu irrigation. Methods Matrine assay was selected to be the indicator for the extraction efficacy. Orthogonal test was used to determine the optimal water amount, extraction time and extraction frequency. Results The best extraction process was to extract 90 minutes twice with the water amount 8 times of the dry herbal material by weight. Conclusion This process is feasible and repeatable. It can be used for the quality control of the preparation.

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Reference (8)

[1]	杨霄,于喜水,金哲雄.苦参生物碱提取工艺研究进展[J].黑龙江医药,2013,26(3):425-427.
[2]	王光函,张宏,姜鸿,等.基于苦参碱含量的中药失眠小复方提取工艺研究[J].时珍国医国药,2015;26(11):2673-2674.
[3]	国家药典委员会.中华人民共和国药典2015年版(一部)[S].北京:化学工业出版社,2015:202-203.
[4]	娄方璐,刁庆春,刘毅,等. 湿疹中医外治处方用药规律分析[J]. 陕西中医,2012,33(1):97-100.
[5]	张翅,马悦,高慧敏,等. 苦参化学成分研究进展[J]. 中国实验方剂学杂志,2014,20(4):205-214.
[6]	智信,陈晓,苏佳灿.苦参碱药理作用研究进展[J].成都中医药大学学报,2017;40(1):123-127.
[7]	吴芳妮,张芊,张春雷. 苦参在T细胞介导的皮肤良恶性疾病中的应用进展[J].中国皮肤性病学杂志,2016,30(8):847-849.
[8]	郭德祥,郭亚楠,李向阳. 苦参碱的提取纯化工艺研究[J]. 河南畜牧兽医(综合版),2013(3):12-14.

[1]	杨霄,于喜水,金哲雄.苦参生物碱提取工艺研究进展[J].黑龙江医药,2013,26(3):425-427.
[2]	王光函,张宏,姜鸿,等.基于苦参碱含量的中药失眠小复方提取工艺研究[J].时珍国医国药,2015;26(11):2673-2674.
[3]	国家药典委员会.中华人民共和国药典2015年版(一部)[S].北京:化学工业出版社,2015:202-203.
[4]	娄方璐,刁庆春,刘毅,等. 湿疹中医外治处方用药规律分析[J]. 陕西中医,2012,33(1):97-100.
[5]	张翅,马悦,高慧敏,等. 苦参化学成分研究进展[J]. 中国实验方剂学杂志,2014,20(4):205-214.
[6]	智信,陈晓,苏佳灿.苦参碱药理作用研究进展[J].成都中医药大学学报,2017;40(1):123-127.
[7]	吴芳妮,张芊,张春雷. 苦参在T细胞介导的皮肤良恶性疾病中的应用进展[J].中国皮肤性病学杂志,2016,30(8):847-849.
[8]	郭德祥,郭亚楠,李向阳. 苦参碱的提取纯化工艺研究[J]. 河南畜牧兽医(综合版),2013(3):12-14.

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Optimization of extraction technology for Toufu irrigation by orthogonal test

doi: 10.3969/j.issn.1006-0111.2018.02.016

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