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Volume 36 Issue 1
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2018  >  36(1): 68-70,79

FU Zhenhe, ZHAO Liang, ZHOU Jin, WANG Xinxia, ZHANG Guoqing, HUANG Yufeng. Determination of paeoniflorin in Chinese traditional herbal preparation Fuzhengpingxiao capsule using HPLC method[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(1): 68-70,79. doi: 10.3969/j.issn.1006-0111.2018.01.014
Citation: FU Zhenhe, ZHAO Liang, ZHOU Jin, WANG Xinxia, ZHANG Guoqing, HUANG Yufeng. Determination of paeoniflorin in Chinese traditional herbal preparation Fuzhengpingxiao capsule using HPLC method[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(1): 68-70,79. doi: 10.3969/j.issn.1006-0111.2018.01.014
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Determination of paeoniflorin in Chinese traditional herbal preparation Fuzhengpingxiao capsule using HPLC method

doi: 10.3969/j.issn.1006-0111.2018.01.014

  • Department of Pharmacy, Eastern Hepatobiliary Surgery Hospital Affiliated to Second Military Medical University, Shanghai 200438, China

  • Received Date: 2017-04-10
  • Rev Recd Date: 2017-12-29
  • Objective To determine the content of paeoniflorin in Fuzhengpingxiao capsule by HPLC method. Methods The content of paeoniflorin were determined by HPLC, and the column was an Agilent Zorbax SB-C18 column (150 mm×4.6 mm, 5 μm); The mobile phase was acetonitrile and 5 mmol/L sodium dihydrogen phosphate (10:90), and the flow rate was set at 1 ml/min. Column temperature was 25℃, detection wavelength was 230 nm, injection volume was 10 μl, and running time was 25 min. Results Paeoniflorin was linear (r=0.999 9) in the concentration of 25.0-500.0 μg/ml, the linear equation was Y=12.65X +43.54, and the average recovery was 92.69% with RSD value was 1.77%. Conclusion The method was easy to operate, reliable and reproducible, which could be used in the determination of paeoniflorin in FuzhengPingxiao capsule.
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    [10] 尹宁宁, 徐华玲, 徐丽华. 白芍中芍药苷含量测定影响因素的实验研究[J]. 中国医药导报, 2009,6(11):43-44.
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Determination of paeoniflorin in Chinese traditional herbal preparation Fuzhengpingxiao capsule using HPLC method

doi: 10.3969/j.issn.1006-0111.2018.01.014
  • Department of Pharmacy, Eastern Hepatobiliary Surgery Hospital Affiliated to Second Military Medical University, Shanghai 200438, China
  • Received Date: 2017-04-10
  • Rev Recd Date: 2017-12-29

Abstract: Objective To determine the content of paeoniflorin in Fuzhengpingxiao capsule by HPLC method. Methods The content of paeoniflorin were determined by HPLC, and the column was an Agilent Zorbax SB-C18 column (150 mm×4.6 mm, 5 μm); The mobile phase was acetonitrile and 5 mmol/L sodium dihydrogen phosphate (10:90), and the flow rate was set at 1 ml/min. Column temperature was 25℃, detection wavelength was 230 nm, injection volume was 10 μl, and running time was 25 min. Results Paeoniflorin was linear (r=0.999 9) in the concentration of 25.0-500.0 μg/ml, the linear equation was Y=12.65X +43.54, and the average recovery was 92.69% with RSD value was 1.77%. Conclusion The method was easy to operate, reliable and reproducible, which could be used in the determination of paeoniflorin in FuzhengPingxiao capsule.

FU Zhenhe, ZHAO Liang, ZHOU Jin, WANG Xinxia, ZHANG Guoqing, HUANG Yufeng. Determination of paeoniflorin in Chinese traditional herbal preparation Fuzhengpingxiao capsule using HPLC method[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(1): 68-70,79. doi: 10.3969/j.issn.1006-0111.2018.01.014
Citation: FU Zhenhe, ZHAO Liang, ZHOU Jin, WANG Xinxia, ZHANG Guoqing, HUANG Yufeng. Determination of paeoniflorin in Chinese traditional herbal preparation Fuzhengpingxiao capsule using HPLC method[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(1): 68-70,79. doi: 10.3969/j.issn.1006-0111.2018.01.014
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