Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 35 Issue 6
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2017  >  35(6): 495-498,529

MA Kaiyuan, ZHANG Yuefan, LI Tiejun. Research progress of peptide compounds in traumatic brain injury[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 495-498,529. doi: 10.3969/j.issn.1006-0111.2017.06.004
Citation: MA Kaiyuan, ZHANG Yuefan, LI Tiejun. Research progress of peptide compounds in traumatic brain injury[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 495-498,529. doi: 10.3969/j.issn.1006-0111.2017.06.004
shu

Research progress of peptide compounds in traumatic brain injury

doi: 10.3969/j.issn.1006-0111.2017.06.004
  • 1.

    School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China

  • 2.

    Department of Pharmacology, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • 3.

    School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China;Department of Pharmacology, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • Received Date: 2017-07-17
  • Rev Recd Date: 2017-10-17
  • Traumatic brain injuries(TBI) have caused severe injuries and deaths all over the world, but so far researchers have not found an effective drug in treating TBI on clinic. However, peptides have gradually been in a hot research with its advantages which include safety and tolerance etc. The neuroprotective and anti-inflammatory effects of several peptide compounds in traumatic brain injury are reviewed in this paper.
  • [1] 惠纪元,龚如,梁玉敏,等. 中国颅脑创伤数据库:短期预后因素分析[J]. 中华神经外科杂志,2014,30(1):56-58.
    [2] 江基尧. 中国颅脑创伤研究的现状与未来[J]. 中华医学杂志,2013,93(23):1761-1762.
    [3] Stein DG,Wright DW. Progesterone in the clinical treatment of acute traumatic brain injury[J]. Expert Opin Investig Drugs,2010,19(7):847-857.
    [4] 王克全,徐寒梅. 多肽类药物的研究进展[J]. 药学进展,2015,39(9):642-650.
    [5] Lee EH,Seo SR. Neuroprotective roles of pituitary adenylate cyclase-activating polypeptide in neurodegenerative diseases[J]. BMB Rep,2014,47(7):369-375.
    [6] Katahira M,Yone K,Arishima Y,et al.The neuroprotective effects of PACAP on spinal cord injury (SCI) in rats[J]. Regul Pept,2003,115(1):49.
    [7] Reglodi D,Kiss P,Lubics A,et al. Review on the protective effects of PACAP in models of neurodegenerative diseases in vitro and in vivo[J]. Curr Pharm Des,2011,17(10):962-972.
    [8] Farkas O,Tamás A,Zsombok A,et al. Effects of pituitary adenylate cyclase activating polypeptide in a rat model of traumatic brain injury[J]. Regul Pept,2004,123(1-3):69-75.
    [9] Vukojevic J,Vrdoljak B,Malekinusic D,et al. The effect of BPC 157 on ischemic/reperfusion injuriesin rat brain[J]. FASEB J,2016,30(1Suppl):705-706.
    [10] Tudor M,Jandric I,Marovic A,et al. Traumatic brain injury in mice and pentadecapeptide BPC 157 effect[J]. Regul Pept,2010,160(1-3):26-32.
    [11] Tohyama Y,Sikirié P,Diksic M. Effects of pentadecapeptide BPC157 on regional serotonin synthesis in the rat brain:alpha-methyl-L-tryptophan autoradiographic measurements[J]. Life Sci,2004,76(3):345-357.
    [12] Amiri-Nikpour MR,Nazarbaqhi S,Ahmadi-Salmasi B,et al. Cerebrolysin effects on neurological outcomes and cerebral blood flow in acute ischemic stroke[J]. Neuropsychiatr Dis Treat,2014,10:2299.
    [13] Sharma HS,Zimmermann-Meinzingen S,Johanson CE. Cerebrolysin reduces blood-cerebrospinal fluid barrier permeability change,brain pathology,and functional deficits following traumatic brain injury in the rat[J]. Ann N Y Acad Sci,2010,1199:125-137.
    [14] Chen CC,Wei ST,Tsaia SC,et al. Cerebrolysin enhances cognitive recovery of mild traumatic brain injury patients:double-blind,placebo-controlled,randomized study[J]. Br J Neurosurg,2013,27(6):803-807.
    [15] álvarez XA,Figueroa J,Muresanu D. Peptidergic drugs for the treatment of traumatic brain injury[J]. Futr Neurol,2013,8(2):175-192.
    [16] Faden AI,Fox GB,Fan L,et al. Novel TRH analog improves motor and cognitive recovery after traumatic brain injury in rodents[J]. Am J Physiol,1999,277(4 Pt 2):R1196-R1204.
    [17] Jain KK. Neuroprotection in traumatic brain injury[J]. Drug Discov Today, 2008,13(23-24):1082-1089.
    [18] Faden AI,Knoblach SM,Cernak I,et al. Novel diketopiperazine enhances motor and cognitive recovery after traumatic brain injury in rats and shows neuroprotection in vitro and in vivo[J].J Cerebr Blood Flow Metabol,2003:342-354.
    [19] Faden AI,Movsesyan VA,Knoblach SM,et al. Neuroprotective effects of novel small peptides in vitro and after brain injury[J]. Neuropharmacology,2005,49(3):410-424.
    [20] Faden AI,Knoblach SM,Movsesyan VA,et al. Novel small peptides with neuroprotective and nootropic properties[J]. J Alzheimers Dis,2004,6(6 Suppl):S93-S97.
    [21] 李淑敏. 促红细胞生成素的临床应用进展[J]. 职业与健康,2013,29(21):2862-2864.
    [22] Corwin HL,Gettinger A,Fabian TC,et al. Efficacy and safety of epoetin Alfa in criticallyⅢ patients[J]. New Engl J Med,2007,357(10):965-976.
    [23] Collino M,Thiemermann C,Cerami A,et al. Flipping the molecular switch for innate protection and repair of tissues:Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin[J]. Pharmacol Ther,2015,151:32-40.
    [24] Robertson CS,Cherian L,Shah M,et al. Neuroprotection with an erythropoietin mimetic peptide (pHBSP) in a model of mild traumatic brain injury complicated by hemorrhagic shock[J]. J Neurotr,2012,29(6):1156-1166.
    [25] Verghese PB,Castellano JM,Holtzman DM. Apolipoprotein E in Alzheimer's disease and other neurological disorders[J]. Lancet Neurol,2011,10(3):241-252.
    [26] Jiang Y,Brody DL. Administration of COG1410 reduces axonal amyloid precursor protein immunoreactivity and microglial activation after controlled cortical impact in mice[J]. J Neurotr,2012,29(13):2332-2341.
    [27] Laskowitz DT,Mckenna SE,Song P,et al. COG1410,a novel apolipoprotein E-basedpeptide,improves functional recovery in a murine model of traumatic brain injury[J]. J Neurotr,2007,24(7):1093-1107.
    [28] 贺杰,庞金伟,吴越,等. 载脂蛋白E短肽COG1410对蛛网膜下腔出血后早期脑水肿的影响[J]. 第三军医大学学报,2016,38(4):350-355.
    [29] Wu Y,Pang J,Peng J,et al. An apoE-derived mimic peptide,COG1410,alleviates early brain injury via reducing apoptosis and neuroinflammation in a mouse model of subarachnoid hemorrhage[J].Neurosci Lett,2016,627:92-99.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2223) PDF downloads(488) Cited by()

Related
Proportional views

Research progress of peptide compounds in traumatic brain injury

doi: 10.3969/j.issn.1006-0111.2017.06.004
  • 1. School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China
  • 2. Department of Pharmacology, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • 3. School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China;Department of Pharmacology, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received Date: 2017-07-17
  • Rev Recd Date: 2017-10-17

Abstract: Traumatic brain injuries(TBI) have caused severe injuries and deaths all over the world, but so far researchers have not found an effective drug in treating TBI on clinic. However, peptides have gradually been in a hot research with its advantages which include safety and tolerance etc. The neuroprotective and anti-inflammatory effects of several peptide compounds in traumatic brain injury are reviewed in this paper.

MA Kaiyuan, ZHANG Yuefan, LI Tiejun. Research progress of peptide compounds in traumatic brain injury[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 495-498,529. doi: 10.3969/j.issn.1006-0111.2017.06.004
Citation: MA Kaiyuan, ZHANG Yuefan, LI Tiejun. Research progress of peptide compounds in traumatic brain injury[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 495-498,529. doi: 10.3969/j.issn.1006-0111.2017.06.004
shu

    HTML

Reference (29)

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return