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ZHAI Xiaobo, WANG Yamin, BAI Rong, HE Zhigao. Clinical pharmacists in promoting the rational use of angiotensin-converting enzyme inhibitors in the CCU[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(5): 472-474,478. doi: 10.3969/j.issn.1006-0111.2017.05.022
Citation: ZHAI Xiaobo, WANG Yamin, BAI Rong, HE Zhigao. Clinical pharmacists in promoting the rational use of angiotensin-converting enzyme inhibitors in the CCU[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(5): 472-474,478. doi: 10.3969/j.issn.1006-0111.2017.05.022

Clinical pharmacists in promoting the rational use of angiotensin-converting enzyme inhibitors in the CCU

doi: 10.3969/j.issn.1006-0111.2017.05.022
  • Received Date: 2016-06-02
  • Rev Recd Date: 2017-05-17
  • Objective To improve the rational use of angiotensin-converting enzyme inhibitors (ACEI). Methods Clinical pharmacists reviewed ACEI use for the patients admitted into coronary heart disease care unit (CCU) during May 2012 to May 2013 to analyze the rational use of ACEI according to the expert consensus standards, guidelines and drug instructions of ACEI without any interventions. Clinical pharmacists intervened the irrational use of ACEI based on the same standard from June 2013 to May 2015. Results By comparing the data before and after intervention, it was found that the percentage of ACEI use increased from 80.1% to 98.9%. The percentage of initial ACEI overdose was dropped from 21.4% to 0.9%, and the percentage of under dose was decreased from 4.7% to 0.5%, which was statistically significant. Conclusion Clinical pharmacists can play a leading role in promoting the rational use of ACEI.
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    [5] Cheng J, Zhang W, Zhang X,et al. Effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on all-cause mortality, cardiovascular deaths, and cardiovascular events in patients with diabetes mellitus: a meta-analysis[J].JAMA Intern Med, 2014,174(5):773-85.
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Clinical pharmacists in promoting the rational use of angiotensin-converting enzyme inhibitors in the CCU

doi: 10.3969/j.issn.1006-0111.2017.05.022

Abstract: Objective To improve the rational use of angiotensin-converting enzyme inhibitors (ACEI). Methods Clinical pharmacists reviewed ACEI use for the patients admitted into coronary heart disease care unit (CCU) during May 2012 to May 2013 to analyze the rational use of ACEI according to the expert consensus standards, guidelines and drug instructions of ACEI without any interventions. Clinical pharmacists intervened the irrational use of ACEI based on the same standard from June 2013 to May 2015. Results By comparing the data before and after intervention, it was found that the percentage of ACEI use increased from 80.1% to 98.9%. The percentage of initial ACEI overdose was dropped from 21.4% to 0.9%, and the percentage of under dose was decreased from 4.7% to 0.5%, which was statistically significant. Conclusion Clinical pharmacists can play a leading role in promoting the rational use of ACEI.

ZHAI Xiaobo, WANG Yamin, BAI Rong, HE Zhigao. Clinical pharmacists in promoting the rational use of angiotensin-converting enzyme inhibitors in the CCU[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(5): 472-474,478. doi: 10.3969/j.issn.1006-0111.2017.05.022
Citation: ZHAI Xiaobo, WANG Yamin, BAI Rong, HE Zhigao. Clinical pharmacists in promoting the rational use of angiotensin-converting enzyme inhibitors in the CCU[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(5): 472-474,478. doi: 10.3969/j.issn.1006-0111.2017.05.022
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