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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2017  >  35(4): 334-336,370

CHEN Yan, ZHANG Mei, WANG Jinping, YANG Feng. The extraction and acute toxicity testing of Moringa oleifera leaves and seeds[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(4): 334-336,370. doi: 10.3969/j.issn.1006-0111.2017.04.011
Citation: CHEN Yan, ZHANG Mei, WANG Jinping, YANG Feng. The extraction and acute toxicity testing of Moringa oleifera leaves and seeds[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(4): 334-336,370. doi: 10.3969/j.issn.1006-0111.2017.04.011
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The extraction and acute toxicity testing of Moringa oleifera leaves and seeds

doi: 10.3969/j.issn.1006-0111.2017.04.011
  • 1.

    Department of Pharmacy, Chinese PLA Army General Hospital, Beijing 100700, China;Institute of Basic Medical Science, Chinese PLA General Hospital, Beijing 100853, China

  • 2.

    Department of Pharmacy, Chinese PLA Army General Hospital, Beijing 100700, China

  • Received Date: 2016-03-15
  • Rev Recd Date: 2017-04-20
  • Objective To test the acute toxicity and determine the safe dose range of Moringa oleifera leaves and seeds. Methods Acute toxicity tests were performed based on the documented experimental designs in Research Methods of Pharmacology of Chinese Traditional Medicine. Results The maximum tolerated dose of the superfine powder and alcoholic-aqueous extract of Moringa oleifera leaves were 0.4 g/20 g and 0.8 g/20 g for mice. The safe dose for human is under or equal to 10 g/50 kg and 20 g/50 kg. Conclusion Moringa oleifera leaves were safe for medical and food use. The further research and development is warranted for this plant.
  • [1] 中国科学院《中国植物》志编辑委员会.中国植物志(第34卷)[M]. 北京:科学出版社, 1999:6.
    [2] 庄杏枚. 辣木,三大杀手的天然克星[J]. 健康之路, 2015(1):53-61.
    [3] 苏科巧,陶亮,黄艾祥. 辣木食品研究进展[J]. 农产品加工·综合刊, 2015(1):72-74.
    [4] 陈 奇.中药药理研究方法学 [M]. 2版.北京:人民卫生出版社, 2006:2.
    [5] 闫 荟,孙晓迪,刘守成,等. 海金护卫散微粉对小鼠抗炎及镇痛作用[J]. 中国实验方剂学杂志, 2011,17(4):157-159.
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The extraction and acute toxicity testing of Moringa oleifera leaves and seeds

doi: 10.3969/j.issn.1006-0111.2017.04.011
  • 1. Department of Pharmacy, Chinese PLA Army General Hospital, Beijing 100700, China;Institute of Basic Medical Science, Chinese PLA General Hospital, Beijing 100853, China
  • 2. Department of Pharmacy, Chinese PLA Army General Hospital, Beijing 100700, China
  • Received Date: 2016-03-15
  • Rev Recd Date: 2017-04-20

Abstract: Objective To test the acute toxicity and determine the safe dose range of Moringa oleifera leaves and seeds. Methods Acute toxicity tests were performed based on the documented experimental designs in Research Methods of Pharmacology of Chinese Traditional Medicine. Results The maximum tolerated dose of the superfine powder and alcoholic-aqueous extract of Moringa oleifera leaves were 0.4 g/20 g and 0.8 g/20 g for mice. The safe dose for human is under or equal to 10 g/50 kg and 20 g/50 kg. Conclusion Moringa oleifera leaves were safe for medical and food use. The further research and development is warranted for this plant.

CHEN Yan, ZHANG Mei, WANG Jinping, YANG Feng. The extraction and acute toxicity testing of Moringa oleifera leaves and seeds[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(4): 334-336,370. doi: 10.3969/j.issn.1006-0111.2017.04.011
Citation: CHEN Yan, ZHANG Mei, WANG Jinping, YANG Feng. The extraction and acute toxicity testing of Moringa oleifera leaves and seeds[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(4): 334-336,370. doi: 10.3969/j.issn.1006-0111.2017.04.011
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